Advancements in hit identification for membrane protein drug discovery
Drug Target Review
APRIL 7, 2025
PoLiPa detergent-free stabilisation of membrane proteins enables the application of fragment-based screening to GPCRs, expanding the methods possible targets and opening the potential to develop novel therapeutics agents as a result. The Adenosine A2a receptor was expressed in insect cells using a baculoviral expression system.
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