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A Visual Guide to Genome Editors

Codon

The core of the CRISPR immune response is a guide RNA (gRNA) that binds to a CRISPR-associated (Cas) protein. Traditional approaches to this problem involve the use of viral vectors , which run the risk of triggering immune responses in patients. Collectively, these repeat-protospacer regions are known as CRISPR arrays.

DNA 81
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Scientists discover network of cells and genes involved in Crohn’s disease complication

Broad Institute

Isselbacher Professor of Medicine at Harvard Medical School, and director of the Center for Computational and Integrative Biology and core member in the Department of Molecular Biology at Massachusetts General Hospital. Lingjia Kong, a research scientist in the Xavier lab, is the first author on the study. and Harry B.

Disease 111
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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

This method was more about serendipity than science. But as molecular biology has advanced, so too has our approach to finding new drugs. Their size and mode of action allow for a broader interaction with target molecules, which can be advantageous in disrupting protein-protein interactions or modulating immune responses.

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A Molecular Biologist’s Advice For Life

LifeSciVC

One thread that has run throughout it has been my passion for science as a lens for looking at the world. In particular, I love connecting science to daily life. Pfizer’s recent campaign around “ Science Will Win ” similarly appealed to the ethos of the power of science to help humanity. Remember life’s Central Dogma.

Science 92
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Gamma delta T cells: a rising star in cancer therapy

Drug Target Review

from 2003 to 2006, covering the biotechnology and life-science tools sectors. Earlier in his career, Mr Ho was responsible for FP&A and operational analysis at CuraGen Corporation and worked as an Associate on the Healthcare Investment Banking team at Cowen, Inc. gammadelta T cells link innate and adaptive immune responses.

Therapies 105
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My Attendance at the 2024 Boston Society Cell and Gene Therapy Conference

Alta Sciences

via Wikimedia Commons My fellow Altascientists and I recently attended the 2024 annual Boston Society Gene & Cell Therapy Conference , held at the wonderful Museum of Science in, of course, Boston, MA. Contact one of our experts today to discuss your gene therapy program.

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A Look Back

Dark Matter Blog

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. 49 years ago, when I was 16 years old, I wanted to do exactly what I am doing now. The ultimate success is incredibly rewarding.