BioPharma Drive: Drug Pricing
MAY 27, 2025
City will receive $46 million from Biogen under the alliance. Elsewhere, Angelini Pharma licensed a rare disease therapy and the FDA refused to review a Savara lung drug.
Science Daily: Pharmacology News
MAY 26, 2025
Contrary to widespread assumptions, the largest shark that ever lived -- Otodus megalodon -- fed on marine creatures at various levels of the food pyramid and not just the top. Scientists analyzed the zinc content of a large sample of fossilized megalodon teeth, which had been unearthed above all in Sigmaringen and Passau, and compared them with fossil teeth found elsewhere and the teeth of animals that inhabit our planet today.
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Covalent Modifiers
MAY 25, 2025
Dandan Zhu, Zijian Zheng, Huixin Huang, Xiaojuan Chen, Shuhong Zhang, Zhuchu Chen, Ting Liu, Guangyu Xu, Ying Fu, Yongheng Chen, European Journal of Medicinal Chemistry , 2025 [link] Fibroblast growth factor receptors (FGFRs) represent promising therapeutic targets in various malignancies, yet the clinical application of FGFR covalent inhibitors has been impeded by several significant challenges, including unquantifiable target engagement, undefined off-target effects, and the emergence of drug
Drugs.com
MAY 23, 2025
FRIDAY, May 23, 2025 A new White House report says todays children are the sickest generation in U.S. history when it comes to chronic disease, and it puts the blame on environmental toxins, poor nutrition and too much screen time.Called the "MA.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drug Target Review
MAY 26, 2025
The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We considered the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The agency recommends manufacturers update their vaccines to target the JN.1 strain. At the same time, HHS head Robert F. Kennedy Jr. is removing guidance that healthy children and pregnant women receive COVID shots.
Science Daily: Pharmacology News
MAY 23, 2025
Scientists create a floss pick that samples cortisol within saliva as a marker of stress and quantifies it with a built-in electrode. The system uses a polymer casting technology that can be adapted to capture a wide a range of markers, such as estrogen for tracking fertility, or glucose for tracking diabetes. Ease of use allows monitoring to be incorporated into many areas of treatment.
Drugs.com
MAY 27, 2025
TUESDAY, May 27, 2025 -- The U.S. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3 percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through.
New Drug Approvals
MAY 26, 2025
Ervogastat CAS 2186700-33-2 Non-alcoholic Steatohepatitis (NASH) with Liver Fibrosis (FAST TRACK – U.S.) 2-[5-[(3-Ethoxy-2-pyridinyl)oxy]-3-pyridinyl]- N -[(3 S )-tetrahydro-3-furanyl]-5-pyrimidinecarboxamide ( S )-2-(5-((3-Ethoxypyridin-2-yl]oxy]pyridin-3-yl)- N -(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide PF 06865571 BSOIY5AKQW 407.4 g/mol, C 21 H 21 N 5 O 4 2-[5-(3-ethoxypyridin-2-yl)oxypyridin-3-yl]- N -[(3 S )-oxolan-3-yl]pyrimidine-5-carboxamide Originator Pfizer Class Amides; Eth
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Covalent Modifiers
MAY 27, 2025
Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C. Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyov, Dirk Scharn, Mark A. Pearson, Johannes Popow, Anna C. Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L. Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John V.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The startup is the latest beneficiary of investors’ appetite for protein-degrading technology, which offers a way to reach drug targets other technologies can’t.
Science Daily: Pharmacology News
MAY 23, 2025
A new experiment encodes quantum information in the motion of the atoms and creates a state known as hyper-entanglement, in which two or more traits are linked among a pair of atoms.
Drugs.com
MAY 29, 2025
THURSDAY, May 29, 2025 These days Americans can agree on few things, but unfortunately, pizza, soup and chicken arent among them, a new study says.Those three foods are some of the main sources of sodium for Americans of all racial and ethnic gro.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
MAY 27, 2025
In the ever-evolving world of content management systems (CMS), there are many options to choose fromWordPress, Joomla, Drupal, and others. But for developers who love clean code, flexibility, and control, October CMS stands out as a modern, elegant solution built on the popular Laravel PHP framework. What is October CMS? October CMS is an open-source, free CMS that makes web building easier without compromising power or flexibility.
Covalent Modifiers
MAY 28, 2025
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, Stephen Wilkinson, Stephanie Harlfinger, Graham Smith, Jason G Kettle, Michael Niedbala, Stefan Kavanagh, Dominic P Williams Toxicology Research , 2025, 14, 3, tfaf054, [link] Interest in inhibiting target proteins through covalent binding mechanisms has increased in the last decade due to the potential for beneficial pharmacological properties.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The demand for fill/finish services has never been greater, how are CDMOs responding?
Science Daily: Pharmacology News
MAY 23, 2025
Daylight can boost the immune system's ability to fight infections.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
MAY 29, 2025
THURSDAY, May 29, 2025 Difficulty sleeping after a mild stroke could be a sign of continuing brain health problems in some people, a new study says.Stroke victims who spent more time in bed struggling to sleep had lower scores on tests of t.
Drug Target Review
MAY 23, 2025
In the ever-evolving landscape of immuno-oncology, managing the side effects of advanced therapies has become just as important as enhancing their efficacy. Among the most concerning complications is cytokine release syndrome (CRS), a potentially life-threatening condition that frequently follows the administration of some CAR T-cell therapies and bispecific antibodies.
Crown Bioscience
MAY 23, 2025
In the evolving landscape of cancer research, the development and validation of effective therapeutic agents depend heavily on preclinical models that can replicate human disease with high fidelity. Among these, syngeneic models have emerged as a vital tool in oncology research, offering a unique balance between experimental control and biological relevance.
BioPharma Drive: Drug Pricing
MAY 27, 2025
Integrated informatics platforms boost R&D speed, data qualityand ROI across BioPharma
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
MAY 22, 2025
Proteins catalyze life by changing shape when they interact with other molecules. The result is a muscle twitching, the perception of light, or a bit of energy extracted from food. The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.
Drugs.com
MAY 29, 2025
THURSDAY, May 29, 2025 Belly flab appears to be a stronger warning sign for psoriasis than fat located elsewhere on the body, a new study says.Fat around the abdomen is more strongly linked to psoriasis risk that total body fat, particularly in w.
Perficient: Drug Development
MAY 27, 2025
In todays world, the Internet of Things (IoT) is revolutionizing industries across the globe by connecting devices, systems, and people in ways that were once unimaginable. From smart homes to advanced manufacturing, IoT is creating new opportunities for innovation, efficiency, and data-driven decision-making. At the forefront of this transformation is Microsoft Azure, a cloud computing platform that has become a powerhouse for IoT operations.
Drug Patent Watch
MAY 27, 2025
"Unlock Hidden Profits in Pharmaceutical R&D: A recent analysis of top-selling medications reveals that companies that closely monitor their competitors' patent portfolios are 3x more likely to achieve a higher return on investment in drug development. By staying one step ahead of the competition, can you revolutionize your approach to pharmaceutical innovation?
BioPharma Drive: Drug Pricing
MAY 29, 2025
The funding was meant to help the U.S. prepare for pandemics triggered by avian flu strains, but now leaves the future of Moderna’s program uncertain.
Science Daily: Pharmacology News
MAY 23, 2025
Researchers united insights from cellular biology, quantum computing, old-fashioned semiconductors and high-definition TVs to both create a revolutionary new quantum biosensor. In doing so, they shed light on a longstanding mystery in quantum materials.
Drugs.com
MAY 29, 2025
THURSDAY, May 29, 2025 Heart disease, strokes and diabetes contribute to many dementia cases in the United States, but the risk is not equal everywhere, a new study says.Overall, more than a third (37%) of U.S. dementia cases are linked to eight c.
Fierce BioTech
MAY 27, 2025
Is it time to go beyond classic design in oncology trials? jgrcic Tue, 05/27/2025 - 11:55 Tue, 05/27/2025 - 11:55 Resource Type Whitepaper Promotion Start Tue, 05/27/2025 - 12:06 Use of healthy volunteers in first-in-human trials with oncology small molecules. Can an alternative approach expedite clinical development of small molecule oncology drugs and benefit patients?
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