Drug Target Review
FEBRUARY 7, 2024
Third, since SARS-CoV-2 replicates faster than common cold coronaviruses, there are larger numbers of virus particles to fragment. Maybe the next pandemic respiratory virus will be an influenza virus rather than a coronavirus. Second, SARS-CoV-2 has many more of these high scoring fragments compared to common cold coronaviruses.
Codon
JUNE 11, 2024
But in 2008 , physicists at the University of Washington made a nanopore sequencer using a protein, called MspA, from Mycobacterium smegmatis, a bacterium first described in the 1880s. A full twelve bases of DNA fit inside of the protein at once, which made it exceedingly difficult to detect individual bases.
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Metabolite Tales Blog
JULY 5, 2023
However, more de novo designed molecules in this “beyond the Rule of 5 chemical space” have emerged, with the first in this class, plerixafor , approved in oncology in 2008. Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. Ayushi Jain and Khalid Mumtaz, 2022. Avicenna J Med 12:154–156.
Metabolite Tales Blog
JULY 5, 2023
2] However, more de novo designed molecules in this “beyond the Rule of 5 chemical space” have emerged, with the first in this class, plerixafor , approved in oncology in 2008. Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. Ayushi Jain and Khalid Mumtaz, 2022. Avicenna J Med 12:154–156.
Drug Target Review
OCTOBER 26, 2023
1 Adeno-associated virus (AAV) vectors are the leading platform for in vivo gene delivery for the treatment of various human diseases. It has been well established that exposure to wild-type AAV results in priming of the immune system against the virus. Adeno-associated virus vector as a platform for gene therapy delivery.
The Pharma Data
JUNE 30, 2021
For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.
PLOS: DNA Science
AUGUST 22, 2024
When Crichton died of cancer in 2008, he left behind a staggering trove of research about an eruption of Mauna Loa on the Big Island of Hawaii. He had the top book, film, and TV series within the same week – twice. Crichton had an MD from Harvard Medical School, but he never practiced medicine. He was too busy creating. BUT WAIT!!!
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