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3-5 These layers of regulation, while essential for animal welfare, make NHP-based studies complex, expensive and time-consuming. However, the last decade has seen a gradual reduction in their use, driven by tightening animal welfare regulations and scientific advances. Are we nearing a post-NHP future? Ncardia, 2024.
” It's not a great place to invest given the capital, entrenched interests, regulations, etc. Five years later, he gave the field the name it now goes by: molecularbiology. My question is: if ARIA felt it had an ARPAnet or a molecularbiology on its hands, how much is too much of your funds focused on that one area?
SRP-001 targets the central nervous system (CNS) by producing N-arachidonoylaminophenol (AM404) in the midbrain’s periaqueductal grey (PAG) region, crucial for pain sensation and regulation. Could you elaborate on the potential market size for SRP-001 and how it fits into the broader landscape of pain therapies?
For example, one can fuse a deactivated Cas9 protein to so-called “transcriptional regulators” to either activate or repress genes without directly editing the genome at all. In May 2025, however, Prime Medicine announced that they would shift their priorities to other diseases instead, including cystic fibrosis.
Held under the theme A Festival of Life Science , Drug Discovery 2025 is a celebration that aims to unite scientists from industry and academia working toward the same goal: improving human health through more effective drug discovery. Dr Dafydd Owen is a Senior Scientific Director at Pfizer with 25 years experience in medicinal chemistry.
AI tool predicts potential drug targets by analyzing cell images By Corie Lok May 13, 2025 Breadcrumb Home AI tool predicts potential drug targets by analyzing cell images Researchers have developed a machine learning model that connects images of DNA structure to gene regulation. Online May 12, 2025. Cell Systems.
Do you like molecularbiology? In attempting that, I will lead you through a frantic tour of information theory and molecularbiology. The rest of your DNA does other important things, like regulating what proteins get made. Well, while the above dance is happening, other sections of DNA are "regulating" it.
The insulin released into the water is a near-perfect molecular match of the insulin produced by the fish to regulate their blood sugar, an example of convergent evolution, or the re-evolution of the same trait in different species. ” Asimov Press (2025). Cite: Whiteman, N. “Toxic Proteins for Drug Discovery.”
By Matthew Cobb The Central Dogma is a linchpin for understanding how cells work, and yet it is one of the most widely misunderstood concepts in molecularbiology. That is pretty much exactly what happens in many microbes; gene regulation responds to environmental stimuli. Cite: Cobb, Matthew. ” Asimov Press (2024).
As we enter 2025, we’ve noticed that our list of ideas has ballooned into the hundreds. Dave Schneider ) Sleep Biology In the Epic of Gilgamesh , the eponymous protagonist was challenged by the Mesopotamian king Utnapishtim to stay awake for 6 days and 7 nights in order to achieve immortality. He was unable to do so.
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