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Time for change: non-human primates in drug research

Drug Target Review

3-5 These layers of regulation, while essential for animal welfare, make NHP-based studies complex, expensive and time-consuming. However, the last decade has seen a gradual reduction in their use, driven by tightening animal welfare regulations and scientific advances. Are we nearing a post-NHP future? Ncardia, 2024.

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Inside ARIA, the UK's Bet to Build Scientific Revolutions

Codon

” It's not a great place to invest given the capital, entrenched interests, regulations, etc. Five years later, he gave the field the name it now goes by: molecular biology. My question is: if ARIA felt it had an ARPAnet or a molecular biology on its hands, how much is too much of your funds focused on that one area?

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SRP-001: redefining pain treatment with a safer, non-opioid analgesic

Drug Target Review

SRP-001 targets the central nervous system (CNS) by producing N-arachidonoylaminophenol (AM404) in the midbrain’s periaqueductal grey (PAG) region, crucial for pain sensation and regulation. Could you elaborate on the potential market size for SRP-001 and how it fits into the broader landscape of pain therapies?

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A Visual Guide to Genome Editors

Codon

For example, one can fuse a deactivated Cas9 protein to so-called “transcriptional regulators” to either activate or repress genes without directly editing the genome at all. In May 2025, however, Prime Medicine announced that they would shift their priorities to other diseases instead, including cystic fibrosis.

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ELRIG Announces Keynote Speakers for Drug Discovery 2025

Elrig

Held under the theme A Festival of Life Science , Drug Discovery 2025 is a celebration that aims to unite scientists from industry and academia working toward the same goal: improving human health through more effective drug discovery. Dr Dafydd Owen is a Senior Scientific Director at Pfizer with 25 years experience in medicinal chemistry.

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AI tool predicts potential drug targets by analyzing cell images

Broad Institute

AI tool predicts potential drug targets by analyzing cell images By Corie Lok May 13, 2025 Breadcrumb Home AI tool predicts potential drug targets by analyzing cell images Researchers have developed a machine learning model that connects images of DNA structure to gene regulation. Online May 12, 2025. Cell Systems.

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How Much Information is in DNA?

Codon

Do you like molecular biology? In attempting that, I will lead you through a frantic tour of information theory and molecular biology. The rest of your DNA does other important things, like regulating what proteins get made. Well, while the above dance is happening, other sections of DNA are "regulating" it.

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