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Persistent challenges with NHP use Despite their biological relevance, using live NHPs in research poses several major challenges: Ethical concerns NHPs, due to their advanced cognition and social behaviour, are at the centre of ongoing ethical debates. Supply chain disruptions Availability is a critical bottleneck in NHP-based research.
Altasciences at ASGCT 2025: An Open Forum for All Things Gene and Cell Therapy | By Kaylyn Koenig aasimakopoulos Thu, 07/10/2025 - 08:00 I recently returned from attending the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting. WHO WAS AT ASGCT 2025? It was exciting to see how much interest the poster generated.
Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies pmjackson Fri, 06/06/2025 - 09:01 By Martin Rougée, Optimization Scientist, Bioanalytical Operations Automation offers several advantages to any industry. Tags Bioanalysis Preclinical Research Weight 15
Expanding access and impact A major step forwards came in February 2025 with the announcement of the BET on Blood for SCD partnership between the National Alliance of Sickle Cell Centers (NASCC) and Terumo Blood and Cell Technologies. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.Available Sickle Cell Anemia.
Researchers have since discovered variants of the protein with additional useful qualities. Researchers have also discovered a slew of small Cas9s — some less than half the size of the S. By cutting DNA with CRISPR, researchers can therefore scramble the genetic code in a way that disables the targeted gene.
By Allessandra DiCorato June 25, 2025 Credit: Xavier and Smillie labs Microscopy image shows intestinal tissue from a Crohn’s patient with fibrosis. Lingjia Kong, a research scientist in the Xavier lab, is the first author on the study. Currently, the only treatment option for these gut “strictures” is surgery.
The UK’s Advanced Research and Invention Agency (ARIA) is often referred to as a “UK DARPA” While ARIA is no DARPA clone, many features of the agency are admittedly DARPA-inspired, such as the use of term-limited program managers, which ARIA calls program directors. But often, that would be a loss for ARIA.
There's a sharp divide between "impressionistic" research that deals with simple predictions and abstract nouns (merely documenting effects and phenomena) and “mechanical research” that attempts to model what we observe in terms of rules and entities. ” Asimov Press (2025). Cite: Slime Mold Time Mold.
The approach has been — and continues to be — a mainstay of biomedical research and the workhorse for producing the mRNA COVID-19 vaccines, which have extended millions of lives, and numerous other therapeutics and diagnostics. Nominations for the 2025 Merkin Prize are now open and will close on December 6, 2024, at 11:59 p.m.
This energy effectiveness is aligned to the Company’s Ambition Zero Carbon programme that commits to zero carbon emigrations from its operations across the world by 2025, and for its entire value chain to be carbon negative by 2030. The life lores cluster in Cambridge The life lores cluster in Cambridge is the most productive in Europe.
The global pain management market is projected to reach about $87 billion by 2025, driven by rising chronic diseases, an ageing population and more surgical procedures. Could you elaborate on the potential market size for SRP-001 and how it fits into the broader landscape of pain therapies?
His T7 expression technology can be used to make large quantities of nearly any RNA or protein and has been for decades, and continues to be, a mainstay of biomedical research and pharmaceutical production. There’s not a single molecularbiology or biochemistry lab I know that doesn’t use T7.” My interest is in basic research."
Held under the theme A Festival of Life Science , Drug Discovery 2025 is a celebration that aims to unite scientists from industry and academia working toward the same goal: improving human health through more effective drug discovery. Dr Dafydd Owen is a Senior Scientific Director at Pfizer with 25 years experience in medicinal chemistry.
Scientists have developed a way to scale up spatial genomics and lower costs By Allessandra DiCorato April 3, 2025 Breadcrumb Home Scientists have developed a way to scale up spatial genomics and lower costs A new computational approach eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue.
AI tool predicts potential drug targets by analyzing cell images By Corie Lok May 13, 2025 Breadcrumb Home AI tool predicts potential drug targets by analyzing cell images Researchers have developed a machine learning model that connects images of DNA structure to gene regulation.
Do you like molecularbiology? In attempting that, I will lead you through a frantic tour of information theory and molecularbiology. I expect this number to rise a bit over time, as the newest methods use deep learning and research is ongoing.) ” Asimov Press (2025). Do you like information theory?
A clinical genomicist harnesses team-based science to help rare-disease patients By Allessandra DiCorato January 7, 2025 Breadcrumb Home A clinical genomicist harnesses team-based science to help rare-disease patients Heidi Rehm convinced labs and scientists to work together and share data. Thats what makes her so convincing.
Rather than using them as toxins per se, the researchers have cleverly turned the tables by incorporating non-proteinogenic amino acids into therapeutic peptides and proteins. Researchers have proposed using alpha amanitin as just such a Trojan horse to fight pancreatic cancer. Credit: Julie Johnson. Credit: Nigel Voaden.
By Matthew Cobb The Central Dogma is a linchpin for understanding how cells work, and yet it is one of the most widely misunderstood concepts in molecularbiology. Crick was aware of at least four kinds of information transfers, all of which had been observed in biochemical studies by researchers at that time.
He also posited the existence of a physical material to explain inheritance, which he called “elementen,” or “elements,” many years before nucleic acid had even been isolated 4 and more than 80 years before British biologists unveiled DNA’s structure and founded the field of molecularbiology.
As we enter 2025, we’ve noticed that our list of ideas has ballooned into the hundreds. million in 2024, according to Cognitive Market Research. As CEO of the UK’s Advanced Research and Invention Agency, turning the ship around is partially Ilan Gur’s job. All of this is possible because of you, our readers.
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