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Time for change: non-human primates in drug research

Drug Target Review

Persistent challenges with NHP use Despite their biological relevance, using live NHPs in research poses several major challenges: Ethical concerns NHPs, due to their advanced cognition and social behaviour, are at the centre of ongoing ethical debates. Supply chain disruptions Availability is a critical bottleneck in NHP-based research.

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Altasciences at ASGCT 2025: An Open Forum for All Things Gene and Cell Therapy | By Kaylyn Koenig

Alta Sciences

Altasciences at ASGCT 2025: An Open Forum for All Things Gene and Cell Therapy | By Kaylyn Koenig aasimakopoulos Thu, 07/10/2025 - 08:00 I recently returned from attending the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting. WHO WAS AT ASGCT 2025? It was exciting to see how much interest the poster generated.

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Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies

Alta Sciences

Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies pmjackson Fri, 06/06/2025 - 09:01 By Martin Rougée, Optimization Scientist, Bioanalytical Operations Automation offers several advantages to any industry. Tags Bioanalysis Preclinical Research Weight 15

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Automated red blood cell exchange: bridging treatment gaps in sickle cell disease care

Drug Target Review

Expanding access and impact A major step forwards came in February 2025 with the announcement of the BET on Blood for SCD partnership between the National Alliance of Sickle Cell Centers (NASCC) and Terumo Blood and Cell Technologies. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.Available Sickle Cell Anemia.

Disease 52
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A Visual Guide to Genome Editors

Codon

Researchers have since discovered variants of the protein with additional useful qualities. Researchers have also discovered a slew of small Cas9s — some less than half the size of the S. By cutting DNA with CRISPR, researchers can therefore scramble the genetic code in a way that disables the targeted gene.

DNA 81
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Scientists discover network of cells and genes involved in Crohn’s disease complication

Broad Institute

By Allessandra DiCorato June 25, 2025 Credit: Xavier and Smillie labs Microscopy image shows intestinal tissue from a Crohn’s patient with fibrosis. Lingjia Kong, a research scientist in the Xavier lab, is the first author on the study. Currently, the only treatment option for these gut “strictures” is surgery.

Disease 111
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Inside ARIA, the UK's Bet to Build Scientific Revolutions

Codon

The UK’s Advanced Research and Invention Agency (ARIA) is often referred to as a “UK DARPA” While ARIA is no DARPA clone, many features of the agency are admittedly DARPA-inspired, such as the use of term-limited program managers, which ARIA calls program directors. But often, that would be a loss for ARIA.