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NGS is evolving: collaboration and tech lead the way

Drug Target Review

Their latest assay processes four to 24 libraries per batch and detects gene amplifications, fusions, deletions and other cancer biomarkers from both DNA and RNA inputs. Next-Generation Sequencing (NGS) is a high-throughput technology that rapidly sequences DNA and RNA, enabling detailed genetic analysis for research and clinical use.

RNA 92
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What single cells are revealing about brain disorders

Drug Target Review

I got my eyes opened to molecular biology, bioinformatics, computational biology and these emerging fields at the time.” Xenium takes this further with in situ analysis at subcellular resolution, detecting RNA and protein molecules directly within tissues using high-resolution imaging.

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What Makes a Mature Science

Codon

Dwarves aren’t made out of individual cells; they don’t have DNA (yet), though they do have eyelids. Its explanatory power wasn’t even reliant on DNA. Even if an understanding of DNA wasn't necessary to come up with the theory of evolution, genes and their underlying pieces are very mechanistic.

Science 79
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Reaching cruising altitude: New discovery tools to target RNA

Dark Matter Blog

Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA. Today, we are pleased to announce that our article describing one such platform: “ PEARL-seq, A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions ” was published in ACS Chemical Biology.

RNA 52
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Next Generation Sequencing (NGS): why is quantifying nucleic acids important? | BMG LABTECH

BMG Labtech

These numbers reflect impressive developments in DNA sequencing technologies but in most cases represent the immediate costs of consumables on the sequencing instrument. 2 DNA sequencing is also reliant on sample processing and DNA library preparation before sequencing as well as bioinformatics and data analysis after sequencing.

DNA 52
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Kickstarting the use of AI for biotechs: part two

Drug Target Review

2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). 5 Several major technology areas are not included above, such as cheminformatics and bioinformatics. Google DeepMind’s new AI can model DNA, RNA, and ‘all life’s molecules’. Alphafold 3.0: the AI protein predictor gets an upgrade.

RNA 59
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Next Generation Sequencing (NGS) in Clinical Trials: Challenges and Opportunities

Vial

Transforming Genomics Research Next-generation sequencing (NGS) enables comprehensive genome sequencing and has transformed genomics research, offering vastly improved capabilities for analyzing DNA and RNA in a high-throughput and cost-effective manner. Satam et al.