Dark Matter Blog

AUGUST 31, 2020

Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA. Today, we are pleased to announce that our article describing one such platform: “ PEARL-seq, A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions ” was published in ACS Chemical Biology.

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Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures.

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Drug Target Review

MAY 24, 2024

2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). 5 Several major technology areas are not included above, such as cheminformatics and bioinformatics. Google DeepMind’s new AI can model DNA, RNA, and ‘all life’s molecules’. The latest exciting advancement is AlphaFold 3, which was just released.

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Drug Target Review

MAY 27, 2024

Caris Life Sciences® (Caris) has been at the forefront of precision medicine. Caris Discovery, the therapeutic research arm of Caris Life Sciences, was launched to address the paucity of novel oncology drug targets and is uniquely poised to discover first-in-class ADC targets.

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Drug Target Review

JULY 24, 2023

The results were published in Proceedings of National Academy of Sciences of United States of America (PNAS). Through phylogenetic analysis and microscopy techniques, they identified a nuclear-encoded apicoplast RNA polymerase σ subunit called ApSigma. The first identification was based on a bioinformatic analysis.

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Broad Institute

AUGUST 11, 2022

The study appears in Science. It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” Most known bacterial defense systems work by sensing viral DNA or RNA, or cellular stress due to the infection.

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Codon

MAY 15, 2023

Every science journalist under the sun has covered this paper (though I recommend Ed Yong’s ). link ) INSPECTR is a diagnostic tool to detect tiny amounts of viral RNA at room temperature. Science Robotics. Science Robotics. Science Translational Medicine. Bioinformatics. Bioinformatics.

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Codon

MAY 15, 2023

Every science journalist under the sun has covered this paper (though I recommend Ed Yong’s ). link ) INSPECTR is a diagnostic tool to detect tiny amounts of viral RNA at room temperature. Science Robotics. Science Robotics. Science Translational Medicine. Bioinformatics. Bioinformatics.

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PLOS: DNA Science

MAY 16, 2024

These factors are converging to enable both identification of novel infectious diseases as well as microbial resistance, before these threats can impact public health, write a team from the European Society for Clinical Microbiology and Infectious Diseases in Frontiers in Science. Work on vaccines ensued too. It closed a year ago. .

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The Pharma Data

MARCH 20, 2021

Bioinformatics in the Faculty. of Medicine and Health Sciences (Ghent University) and. Biogazelle, an innovative bioanalytical services company offering RNA and. study RNA virus replication and virus-host interactions and in particular the use of single-cell proteomics to aid in this research. Highlight #2 Professor Jo.

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Codon

APRIL 16, 2023

BMC Bioinformatics. Read Basic Science *Noncoding translation mitigation. Science Advances. Read Open science and data sharing in cognitive neuroscience with MouseBytes and MouseBytes+. Read An RNA-based system to study hepatitis B virus replication and evaluate antivirals. Science Advances. McCafferty C.L.

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Codon

AUGUST 28, 2024

National Science Advisory Board for Biosecurity urged the U.S. 5 But it could match up to one of the threats in your reference database, so you opt to throw a battery of bioinformatics tools at it. BLAST is covered in every introductory bioinformatics course and the 1990 paper introducing has over 110,000 citations.

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Codon

AUGUST 10, 2023

Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Science (2018). Science (2017). Science (2010). Science (2016). Science (2023). Politics and the Life Sciences (2009). Science (2014). Trends in Plant Science (2015). Science (2022).

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Codon

AUGUST 10, 2023

Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Science (2018). Science (2017). Science (2010). Science (2016). Science (2023). Politics and the Life Sciences (2009). Science (2014). & Gersbach C.A. PNAS (2008). Nature (2016).

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