Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. His mother had a presentation of the disease that suggested her immune system was already on the job.

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Codon

APRIL 2, 2023

But now, by studying DNA extracted from microbes in the blood of almost 10,000 healthy people, this paper shows that there is no such thing. Read Transcription factors bind to DNA and control gene expression. They tend to “group up” in cells. Molecular Systems Biology. Nature Microbiology. Meeussen J.V.W.

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Codon

APRIL 30, 2023

2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. kilobases” of DNA into a plant genome. (My From Zhang et al.

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Codon

APRIL 30, 2023

2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. kilobases” of DNA into a plant genome. (My From Zhang et al.

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Vaccine DNA Engineering RNA 52

BMG Labtech

MARCH 8, 2023

In biology , scientific research on cell metabolism focuses on different topics such as understanding the fundamental metabolic processes, metabolic changes and their role in diseases (including cancer cell and tumor metabolism), the development of therapies, the identification of unknown metabolic processes and metabolites, etc.

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Codon

NOVEMBER 1, 2024

Amodei also imagines the ways AI could accelerate biological research and yield miraculous cures in the 21st century; everything from the prevention and treatment of nearly all infectious and inherited diseases to the elimination of most cancers. This essay focuses on how we might do both, specifically for the cell. Even the humble E.

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Codon

APRIL 9, 2023

.” This technology could be used to design protein therapeutics that can bind to, and “shut down,” harmful or misfolded proteins in living cells. Thousands of transcription factors — proteins that bind DNA and control gene expression — were studied in human cells. Nature Cell Biology.

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Codon

SEPTEMBER 22, 2024

During this process, the cells’ genomes ditch their methyl groups, an important epigenetic mark. Erasing methyl groups on DNA is necessary for normal egg and sperm development. Reaching the oogonia stage marked an impressive achievement in germ cell biology, because previous methods only went up to the PGC stage.

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Broad Institute

MAY 29, 2025

New technique expands cells to sequence DNA and capture fine structural details By Allessandra DiCorato May 29, 2025 Breadcrumb Home New technique expands cells to sequence DNA and capture fine structural details Using this method, scientists discovered key protein and gene activity changes in aging and in a rare disease called progeria.

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Codon

APRIL 16, 2023

Short DNA strands were discovered that can specifically and tightly bind to zinc and cadmium ions. Perhaps there is now a way to use DNA to extract metals: You could fuse the DNA strands to an antibody, coat them onto electronics, and then use a column to isolate the DNA:metal compounds? Nature Chemical Biology.

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Engineering DNA RNA Science 52

Broad Institute

MAY 12, 2025

By Allessandra DiCorato May 12, 2025 Credit: Allison Colorado, Broad Communications A fellow in Broad's Gene Regulation Observatory, Bo Xia studies how the structure of the genome determines cell fate in both health and disease. Xia went on to earn a PhD in stem cell biology from the New York University Grossman School of Medicine.

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DNA Regulations Cell Biology Disease 81

Codon

APRIL 8, 2025

Experiments performed with the bacterium Streptococcus pneumoniae not only led to the discovery of DNA as the principal hereditary molecule but also yielded early tools for genetic engineering. The study of RNA tumor viruses revealed reverse transcriptase , an enzyme integral in studying RNA biology.

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RNA DNA Laboratories Virus 100

Codon

AUGUST 10, 2023

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

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Codon

AUGUST 10, 2023

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

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