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The Current State of Biotransformation Science 2024

Metabolite Tales Blog

The paper gives a useful insight into the most commonly used in vitro MetID practices across 26 pharma companies, and crucially reveals how effective these systems are at predicting circulating human metabolites. Hypha’s clients range from small through to large pharma companies.

Science 52
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A Lesson in History: Assessing Trial Performance Data for Future Trial Design

H1 Blog

Clinical trial success is a key factor for pharma companies when designing and recruiting patients into trials. In a recent article in Clinical Leader , Randy Krauss, head and executive director of metrics, analytics, and performance, Merck & Co., There is a tendency to want to measure everything.”

Trials 52
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The Power of AI in Drug Discovery and Development

The Connected Lab

Companies such as Cyclica have developed software that matches the biophysical and biochemical properties of millions of molecules to the structures and properties of approximately 150,000 proteins to uncover molecules that are likely to bind to a target 2. A Tough Road: Cost To Develop One New Drug Is $2.6 Nature , vol.

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Pfizer CMO Steps Down, Stanford Professor to Transition into Role

The Pharma Data

Rothenberg did not provide any information as to what his next role may be – whether he will take over the helm of a pharma company or assume a role on one or more boards of directors. I have every confidence in her continued success in this new role,” Rothenberg said.

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Metabolite Bioanalysis

Metabolite Tales Blog

Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group A Metabolite Bioanalysis Working Group comprised of experts from 14 different pharma companies have proposed recommendations around best practice in metabolite bioanalysis during drug development.

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Women in STEM with Gilda Ascione

Drug Target Review

Looking ahead, what exciting developments or advancements do you foresee in your field of STEM, and how do you envision your own research contributing to those future innovations?

Doctors 97
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Ultimovacs ASA Initiates FOCUS Phase II Trial for Universal Cancer Vaccine, UV1, in Head and Neck Cancer Patients Receiving Pembrolizumab

The Pharma Data

The FOCUS trial is Ultimovacs’ fourth Phase II clinical trial with UV1 and comes in addition to the collaboration Phase II trial announced in May 2020. “We To date, UV1 has been tested in four phase I clinical trials in a total of 82 patients and maintained a positive safety and tolerability profile as well as encouraging signals of efficacy.

Vaccine 52