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Automated red blood cell exchange: bridging treatment gaps in sickle cell disease care

Drug Target Review

Despite recent advances in gene therapy for sickle cell disease (SCD) , automated red blood cell exchange (aRBCX) remains a cornerstone therapy that plays a vital yet underutilised role in managing complications and enhancing quality of life for millions living with this devastating condition worldwide.

Disease 52
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Edwin Cohn and the Harvard Blood Factory

Codon

The same team also invented several other products that proved useful for treating battlefield injuries, including gamma globulins to inoculate soldiers against diseases and fibrin film to minimize bleeding during brain surgeries. In 1929 and 1930, two medical doctors working with Cohn — George R. Minot and William P.

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Scientists discover network of cells and genes involved in Crohn’s disease complication

Broad Institute

Related news Single-cell analysis of Crohn’s disease reveals a detailed picture of inflammation in the gut Up to half of patients with Crohn’s disease, an inflammatory bowel disease, develop a complication called fibrosis, where the gut becomes scarred and obstructed, causing pain and bloating.

Disease 111
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Alzheimer’s disease: driving advancements with precision medicine

Drug Target Review

How does precision neuroscience differ from traditional approaches in the treatment of neurodegenerative diseases, and what advantages does it offer? Traditionally, Alzheimer’s disease is diagnosed by clinical examination, medical history and cognitive testing. We believe we are at a breakthrough moment in Alzheimer’s disease research.

Disease 59
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How organoids can redefine pre-clinical research

Drug Target Review

Moreover, their intricate 3D structure and cellular diversity offer a more precise replication of specific structures and functions, making them promising candidates in disease modelling and drug testing. CRISPR engineering in organoids for gene repair and disease modelling. Human organoids in basic research and clinical applications.

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Precision Medicine – it’s not just for oncology anymore

The Pharma Data

Researchers are also using sophisticated machine learning and artificial intelligence to illuminate predictive relationships from highly complex and multi-modal data, including clinical, molecular, and digital data. These analytical tools are giving teams a look at diseases at a digital pathology level. Source link.

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Women in Stem August: Meet Theonie Anastassiadis

Drug Target Review

I then chose to do my doctoral research at the Perelman School of Medicine at the University of Pennsylvania, which provided me with great scientific training, critical thinking, and communication skills. in cell and molecular biology with a focus in cancer biology from the Perelman School of Medicine at the University of Pennsylvania.

Science 98