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Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

Science Daily: Pharmacology News

A tiny, four-fingered 'hand' folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, researchers report.

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Scientists can reverse brain aging in fruit flies by preventing buildup of a common protein

Science Daily: Pharmacology News

Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline.

DNA 297
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Researchers devise new way to target and correct disease-related proteins

Broad Institute

Also featured are the FKBP12 binding motif (light blue triangle), the DNA barcode (red double helix), and the combinatorial library element (red hexagon). Related groups Xavier lab Over the past two decades, large genetic studies have linked tens of thousands of DNA variants to thousands of human traits and diseases.

Disease 139
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NGS is evolving: collaboration and tech lead the way

Drug Target Review

Research by Markets and Markets projects the market to grow from $12.13 1 Emergen Research attributes this to the advantages of high-throughput sequencing technologies and declining sequencing costs​. 2 This trend reflects the increasing demand for genomic sequencing in research, clinical diagnostics and other applications.

RNA 91
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Scientists engineer CRISPR enzymes that evade the immune system

Broad Institute

Researchers at the Broad Institute of MIT and Harvard and Cyrus Biotechnology have now engineered two CRISPR nucleases, Cas9 and Cas12, to mask them from the immune system. The study was led by Feng Zhang , a core institute member at the Broad and an Investigator at the McGovern Institute for Brain Research at MIT.

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The next phase of the multiomics evolution, powered by AI

Drug Target Review

Combining genomics with transcriptomics, proteomics, metabolomics, spatial profiling and cellular imaging, will enable researchers to move beyond single-variable analysis and begin to see the biological system as a whole. Enter multiomics Multiomics is designed to solve this problem by observing multiple molecular layers simultaneously.

RNA 71
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Scientists create next generation of tools in battle against brain disease

Broad Institute

Researchers from around 29 universities and institutions across North America have teamed up to create a large, versatile, and effective arsenal of new biological tools that will play a critical role in the battle against brain disease. Ben-Simon et al.) and striatum ( Hunker et al. Ben-Simon et al.) and striatum ( Hunker et al.

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