Fri.May 02, 2025

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HHS, NIH Unveil Vaccine Initiative to Protect Against Future Pandemics

Drugs.com

FRIDAY, May 2, 2025 -- The U.S. Department of Health and Human Services and the National Institutes of Health announced a new initiative called "Generation Gold Standard" to develop next-generation, universal vaccines using a beta-propiolactone.

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Loss of sea ice alters the colors of light in the ocean

Science Daily: Pharmacology News

The disappearance of sea ice in polar regions due to global warming not only increases the amount of light entering the ocean, but also changes its color. These changes have far-reaching consequences for photosynthetic organisms such as ice algae and phytoplankton.

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RFK Jr. to Change Vaccine Testing Rules

Drugs.com

FRIDAY, May 2, 2025 U.S. Health and Human Services Secretary Robert F. Kennedy Jr. plans to change how vaccines are tested in the U.S., a decision that could impact how quickly and widely vaccines are made available. The department said the new p.

Vaccine 278
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Scientists discover key to taming unrest at Italy's Campi Flegrei

Science Daily: Pharmacology News

New research shows that elevation changes and earthquakes in Italy's Campi Flegrei volcanic area are caused by rising pressure in a geothermal reservoir -- not magma or its gases, as commonly thought. Channeling water runoff or lowering groundwater levels could reduce risks for surrounding communities.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Common Diabetes Drug, Metformin, Effective Against Knee Arthritis Pain

Drugs.com

FRIDAY, May 2, 2025 -- A common diabetes drug can be repurposed to help overweight and obese people with knee arthritis, a new study says. Metformin reduced knee arthritis pain during a six-month treatment period, potentially delaying the need for.

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More Trending

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Medetomidine, a Pet Sedative, Spreads in U.S. Illegal Drug Supply

Drugs.com

FRIDAY, May 2, 2025 A sedative used in animals is showing up more often in illegal drugs and may be making opioid overdoses harder to treat, U.S. health officials warn.The drug, called medetomidine, is used by veterinarians to sedate pets. It's s.

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Antivenom neutralizes the neurotoxins of 19 of the world's deadliest snakes

Science Daily: Pharmacology News

By using antibodies from a human donor with a self-induced hyper-immunity to snake venom, scientists have developed the most broadly effective antivenom to date, which is protective against the likes of the black mamba, king cobra, and tiger snakes in mouse trials. The antivenom combines protective antibodies and a small molecule inhibitor and opens a path toward a universal antiserum.

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Mindfulness Meditation Counters Opioid Cravings

Drugs.com

FRIDAY, May 2, 2025 -- Mindfulness meditation can help rewire the brain to reduce opioid cravings in people addicted to narcotics, a new study says.People assigned to mindfulness training had 50% less opioid cravings than others who received.

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The all-female Korean Haenyeo divers show genetic adaptions to cold water diving

Science Daily: Pharmacology News

The Haenyeo, a group of all-female divers from the Korean island of Jeju, are renowned for their ability to dive in frigid waters without the aid of breathing equipment -- even while pregnant. A study shows that the divers' remarkable abilities are due to both training and genetic adaptation, including gene variants associated with cold tolerance and decreased blood pressure.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Your Loving Partner Can Protect You From Chemo Brain

Drugs.com

FRIDAY, May 2, 2025 A cancer patients bond with their partner can be a key factor in helping them ward off chemotherapy-related brain fog, a new study saysPatients in a satisfying intimate relationship were more likely to resist chemo brain, th.

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The secret to happiness lies within you, or society -- or both

Science Daily: Pharmacology News

What is the secret to happiness? Does happiness come from within, or is it shaped by external influences such as our jobs, health, relationships and material circumstances? A new study shows that happiness can come from either within or from external influences, from both, or neither -- and which is true differs across people.

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More Than 1.8 Million Ninja Pressure Cookers Recalled for Burn Risk

Drugs.com

FRIDAY, May 2, 2025 More than 1.8 million Ninja Foodi pressure cookers are being recalled due to a risk of burns, according to the U.S. Consumer Product Safety Commission (CPSC).The recall affects roughly 1,846,400 Ninja Foodi OP300 Series M.

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Amgen’s Stelara biosimilar gets off to fast start

BioPharma Drive: Drug Pricing

Sales of the company’s copycat to J&J’s blockbuster medicine reached $150 million in the first quarter, adding to a surge in revenue for Amgen's biosimilar business.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Middle-Age Exercise Protects Brain Against Alzheimer's

Drugs.com

FRIDAY, May 2, 2025 Want to protect your aging brain? Get off the couch and get moving, researchers urge.Boosting exercise in middle age might help people prevent Alzheimers disease, a new study says.People who increased their physical activity t.

Disease 245
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Glecirasib, a potent and selective covalent KRAS G12C inhibitor exhibiting synergism 2 with cetuximab or SHP2 inhibitor JAB-3312

Covalent Modifiers

Wang, P., Sun, X., He, X., Kang, D., Liu, X., Liu, D., Li, A., Yang, G., Lin, Y., Li, S., Wang, Y., & Wang, Y. Cancer research communications , 2025 [link] Clinical studies have demonstrated the antitumor efficacy of covalent KRAS G12C inhibitors in treating advanced/metastatic cancers. In the current study, we report the preclinical characteristics of a specific KRAS p.G12C covalent inhibitor, glecirasib.

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Common Diabetes Drug Effective Against Knee Arthritis Pain

Drugs.com

FRIDAY, May 2, 2025 -- A common diabetes drug can be repurposed to help overweight and obese people with knee arthritis, a new study says.Metformin reduced knee arthritis pain during a six-month treatment period, potentially delaying the need for.

Drugs 240
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Cytokinetics reveals unexpected delay; AstraZeneca combo therapy hits in asthma

BioPharma Drive: Drug Pricing

The FDA pushed back its decision date on Cytokinetics’ heart drug, while AstraZeneca got Phase 3 results that could help it expand use of a top drug.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Scooter Riders Were High Or Drunk In A Quarter Of Wrecks

Drugs.com

FRIDAY, May 2, 2025 -- Dont drink and drive is a message the public has largely accepted.Now how about dont drink and scoot?A quarter of people injured in electric scooter accidents were drunk or high when their mishap occurred, researchers rec.

Research 179
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CEFILAVANCIN

New Drug Approvals

CEFILAVANCIN, TD-1792 CAS 722454-12-8 C 87 H 96 Cl 3 N 16 O 28 S 2 , 1984.28 F76229E21M Vancomycin, 26-[[[3-[[( Z )-[1-(2-amino-5-chloro-4-thiazolyl)-2-[[(6 R ,7 R )-2-carboxy-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl]amino]-2-oxoethylidene]amino]oxy]propyl]amino]carbonyl]-26-decarboxy- 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-[(3-{[(1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-d

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Perficient Wins 2025 Delivery Award at Appian World for Second Consecutive Year

Perficient: Drug Development

Perficient is honored to announce weve been named the 2025 Appian Partner Impact and Excellence Award winner for Delivery , marking the second consecutive year we’ve received this prestigious recognition. This award celebrates our continued commitment to delivering rapid, high-quality outcomes on the Appian Platform that consistently exceed client expectations across industries.

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Download the SureChEMBL2.0 data: major update!

The ChEMBL-og

Dear SureChEMBL users, This is our second blog post from our series related to SureChEMBL2.0. If you missed the first one , you should take 5 minutes to read it. We know that for many of you, not being able to download new patent data from SureChEMBL for several months has had a significant impact on your work. Please rest assured that halting the data release was not a decision taken lightly.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Perficient is Headed to Salesforce Connections 2025: Here’s What You Need to Know

Perficient: Drug Development

Salesforce Connections 2025 is quickly approaching, and Perficient is excited to be part of it. On June 1112, were heading to McCormick Place in Chicago and joining virtually on Salesforce+ to connect with marketers, commerce leaders, and innovators shaping the future with AI. Heres what you need to know before the event: When and Where: Dates: June 1112, 2025 Location: McCormick Place, Chicago Online Access: Available via Salesforce+ Why It Matters: Connections is where the future of mar

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From Siloed to Synchronized: The Competitive Case for Omnichannel Alignment

Fierce BioTech

From Siloed to Synchronized: The Competitive Case for Omnichannel Alignment This white paper explores three brand personas based on the current stage of their journey to omnichannel synchronization. It then explains how marketing leaders can empower change agents to progress further on the path, including the resources and KPIs they can use to track that progression and prove its value to the business. sdees Fri, 05/02/2025 - 09:05 This white paper explores three brand personas based on the curr

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How to Plan Biosimilar Clinical Trials in India: Regulations, Process, Benefits, and Data Standards …

ProRelix Research

Efficient biosimilar clinical trials in India follow regulatory guidelines, structured processes, key benefits, and data standards for USFDA and EMA submissions. Biosimilar clinical trials in India are witnessing growing global […] The post How to Plan Biosimilar Clinical Trials in India: Regulations, Process, Benefits, and Data Standards … appeared first on ProRelix Research.

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Unlock More from Salesforce with the PrecisionIQ Assessment

Perficient: Drug Development

Your Salesforce platform holds massive potential but are you getting the most out of it? With our PrecisionIQ Assessment, Perficient gives enterprise teams a clear view of whats working, whats not, and whats next. If AI feels out of reach, adoption is stalling, or ROI is hard to prove, the problem isnt the platform, its the gaps between people, process, and data.

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Unlocking the Gate: The Critical First 24 Hours of Patient Hub Engagement

Drug Channels

Todays guest post comes from Kristine McGaughey, Vice President, Implementation at ConnectiveRx and Sam Blake, SVP, Hub Product at ConnectiveRx. Sam and Kristine discuss the importance of the first 24 hours of a patients engagement with a hub services program. They outline five reasons why two componentspatient enrollment and successful benefits verificationdictate the effectiveness of a patient support program.

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Epigenetic Modifications: Their Role in iPSC Reprogramming and Differentiation

Reprocell

Classic epigenetic modifications include DNA methylation and histone modifications as well as more broadly chromatin accessibility and non-coding RNAs. Epigenetic mechanisms enable heritable changes in gene expression that occur without altering the underlying DNA sequence. The various epigenetic layers act to control DNA accessibility and chromatin structure, which defines transcription factor binding and downstream gene regulation.

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FDA CVM vs. USDA CVB: Understanding the Differences in Veterinary Drug and Biologic Approvals 

DS in Pharmatics

Introduction Navigating the regulatory landscape for veterinary pharmaceuticals and biologics can be complex. The U.S. Food and Drug Administrations Center for Veterinary Medicine (FDA CVM) and the U.S. Department of Agricultures Center for Veterinary Biologics (USDA CVB) oversee different aspects of veterinary product approvals.

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SureChEMBL2.0 announcement

The ChEMBL-og

Dear SureChEMBL users, Last year, we asked for your feedback on what you wanted to see next from SureChEMBL. Your input didnt disappear into the voidquite the opposite! While it may have seemed quiet on the surface, we've been working hard behind the scenes: fixing bugs, implementing new features, and laying the groundwork for major improvements. Today, were excited to share that weve reached a significant milestoneand were marking the occasion with a new name.

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