Wed.Apr 23, 2025

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Scientific path to recouping the costs of climate change

Science Daily: Pharmacology News

A new study lays out a scientific framework for holding individual fossil fuel companies liable for the costs of climate change by tracing specific damages back to their emissions. The researchers use the tool to provide the first causal estimate of economic losses due to extreme heat driven by emissions. They report that carbon dioxide and methane output from just 111 companies cost the world economy $28 trillion from 1991 to 2020, with the five top-emitting firms linked to $9 trillion of those

Research 314
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Microplastics Could Be Contributing To Clogged Arteries

Drugs.com

WEDNESDAY, April 23, 2025 Microplastics could be contributing to clogged arteries, increasing peoples risk of heart attack or stroke, a new study says.Fatty plaques in neck arteries can contain more than 50 times as much microplastics as are fou.

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Newborns living near trees tend to be healthier: New data suggests it's not because healthier people reside near parks

Science Daily: Pharmacology News

The link between proximity to greenspace -- including trees and parks-- and healthy birth outcomes is well established. Now new data adds to our understanding of these health benefits, accounting for other factors that may influence this link, such as education, income and body mass index, but also taking the body of knowledge a step further by exploring the effect of residing near newly planted trees.

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Antibiotics Might Increase Risk of Childhood Asthma, Allergies

Drugs.com

WEDNESDAY, April 23, 2025 -- Overuse of antibiotics might increase kids risk of developing asthma and allergies, by disrupting their gut bacteria during a crucial stage of child development, a new study says.Exposure to antibiotics prior to age 2 i.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Scientists have found a way to 'tattoo' tardigrades

Science Daily: Pharmacology News

If you haven't heard of a tardigrade before, prepare to be wowed. These clumsy, eight-legged creatures, nicknamed water bears, are about half a millimeter long and can survive practically anything: freezing temperatures, near starvation, high pressure, radiation exposure, outer space and more. Researchers took advantage of the tardigrade's nearly indestructible nature and gave the critters tiny 'tattoos' to test a microfabrication technique to build microscopic, biocompatible devices.

Research 219

More Trending

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Childhood exposure to bacterial toxin may be triggering colorectal cancer epidemic among the young

Science Daily: Pharmacology News

An international team has identified a potential microbial culprit behind the alarming rise in early-onset colorectal cancer: a bacterial toxin called colibactin. Scientists report that exposure to colibactin in early childhood imprints a distinct genetic signature on the DNA of colon cells -- one that may increase the risk of developing colorectal cancer before the age of 50.

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FDA Approves Dupixent for Chronic Spontaneous Urticaria

Drugs.com

WEDNESDAY, April 23, 2025 -- The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adults and adolescents with chronic spontaneous urticaria.The approval is for patients 12 years and older who remain.

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Remembering the cold: Scientists discover how memories control metabolism

Science Daily: Pharmacology News

New multidisciplinary research shows that the brain forms memories of cold experiences and uses them to control our metabolism. The study shows that cold memories form in the brain -- and map out how they subsequently drive thermoregulation. The discovery may have important applications in therapies designed to treat a range of disorders -- from obesity to cancer -- in which thermoregulation and metabolism (or a lack of control in this area) plays a role, as well as opening the door to more fund

Therapies 174
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Bristol Myers’ prized schizophrenia drug stumbles in testing

BioPharma Drive: Drug Pricing

A late-stage study found Cobenfy wasn’t better than a placebo as an add-on to atypical antipsychotics. Some analysts view the failure as a “significant hit” to the drug’s commercial outlook.

Drugs 167
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Psychedelics can reverse neuroimmune interactions that boost fear

Science Daily: Pharmacology News

A new study suggests that fear and the immune system are connected in previously unknown ways. Researchers found that the immune system can influence stress and fear behaviors by changing how brain cells communicate.

Research 268
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Mood Disorders Have Increased Among Kids, Teens

Drugs.com

WEDNESDAY, April 23, 2025 -- Depression and anxiety have been increasing steadily among children and teenagers in recent years, a new study says.More than 1 in 10 children (10.6%) suffered from anxiety in 2022, up from 7.1% in 2016, researchers.

Research 162
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By 15 months, infants begin to learn new words for objects, even those they've never seen

Science Daily: Pharmacology News

A new study by developmental scientists offers the first evidence that infants as young as 15 months can identify an object they have learned about from listening to language -- even if the object remains hidden.

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German antibody maker valued at $1.6B in blank-check merger

BioPharma Drive: Drug Pricing

The startup, Veraxa, has $253 million in cash and is raising a crossover funding round to support a pipeline of T cell engagers and bispecific drugs for cancer.

Drugs 157
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Parts of our DNA may evolve much faster than previously thought

Science Daily: Pharmacology News

A team of researchers has used advanced DNA sequencing to develop the most comprehensive atlas yet of genetic change through generations, laying the foundations for new insights into the roots of human disease and evolution.

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Roche looks to a Flagship startup in search of new immune drugs

BioPharma Drive: Drug Pricing

Repertoire Immune Medicines will get $35 million upfront, and possibly $730 million more, in a deal to help Roche’s Genentech division unearth T-cell targeting therapies for inflammatory diseases.

Therapies 157
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How bacteria in our aging guts can elevate risk of leukemia and perhaps more

Science Daily: Pharmacology News

Scientists have discovered a surprising new connection between gut health and blood cancer risk one that could transform how we think about aging, inflammation, and the early stages of leukemia.

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Early Menopause Might Mean Greater Age-Related Brain Decline

Drugs.com

WEDNESDAY, April 23, 2025 -- Early menopause could be a warning sign for future age-related brain decline, a new study says.Women who entered menopause before 40 had a greater cognitive decline than women who entered menopause after 50, according.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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World on course to trigger multiple climate 'tipping points' unless action accelerates

Science Daily: Pharmacology News

Multiple climate 'tipping points' are likely to be triggered if global policies stay on their current course, new research shows.

Research 219
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Muscle Quality Could Be Key To Successful Hip Replacement

Drugs.com

WEDNESDAY, April 23, 2025 -- Folks are less likely to recover successfully from a total hip replacement if they have poor muscle quality going into the procedure, a small-scale study says.Patients whose MRI scans revealed fatty hip muscle prior to.

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Engineering a robot that can jump 10 feet high -- without legs

Science Daily: Pharmacology News

Inspired by the movements of a tiny parasitic worm, engineers have created a 5-inch soft robot that can jump as high as a basketball hoop. Their device, a silicone rod with a carbon-fiber spine, can leap 10 feet high even though it doesn't have legs. The researchers made it after watching high-speed video of nematodes pinching themselves into odd shapes to fling themselves forward and backward.

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Teen Cannabis Use Rises in Canada After Edibles Are Legalized

Drugs.com

WEDNESDAY, April 23, 2025 Teen cannabis use rose significantly in parts of Canada after edibles were legalized, a new study shows.The study found a 26% increase in teen cannabis use in provinces that began selling cannabis edibles and extracts in.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Skeletal evidence of Roman gladiator bitten by lion in combat discovered

Science Daily: Pharmacology News

Bite marks found on a skeleton discovered in a Roman cemetery in York have revealed the first archaeological evidence of gladiatorial combat between a human and a lion.

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[Podcast] Behind the Breakthroughs: How Almac Powers Clinical Trial Success with Care

BioPharma Drive: Drug Pricing

Agile biopharma firms are driving breakthroughs. Learn how they ensure clinical trial success in this podcast.

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Bacteria killing material creates superbug busting paint

Science Daily: Pharmacology News

A bacteria killing coating created by scientists has been used in trials of a new paint that can be applied to a range of surfaces to effectively kill bacteria and viruses, including difficult to kill species such as MRSA, flu and COVID-19.

Virus 216
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Psilocybin Use Dramatically Increasing In U.S.

Drugs.com

WEDNESDAY, April 23, 2025 Recreational use of magic mushroom psilocybin skyrocketed in the U.S. during the early 2020s, as states began toying with legalization of the psychedelic drug, a new study says.The number of adults 30 and older who had.

Drugs 130
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Melting glaciers at the end of the Ice Age may have sped up continental drift, fueled volcanic eruptions

Science Daily: Pharmacology News

Scientists believe that the motion of Earth's continents through plate tectonics has been largely steady over millions of years. New research, however, suggests this drift can speed up or slow down over relatively short time periods.

Research 209
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The Impact of Drug Patent Expiration: Financial Implications, Lifecycle Strategies, and Market Transformations

Drug Patent Watch

"Patent Expiration: The $1.4 Trillion Wake-Up Call for the Pharmaceutical Industry As the pharmaceutical landscape continues to shift, one thing is clear: the expiration of drug patents is no longer a footnote in the industry's financials. According to a recent analysis, the loss of exclusivity for top-selling medications will result in a staggering $1.4 trillion in lost revenue by 2025.

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Scientists trick the eye into seeing new color 'olo'

Science Daily: Pharmacology News

Scientists have created a new platform called 'Oz' that uses laser light to control up to 1,000 photoreceptors in the eye at once. Using Oz, the researchers showed people images, videos and a new, ultra-saturated shade of green that they have named 'olo.' The platform could be used to probe the nature of color vision and provide new insight into human sight and vision loss.

Research 205
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Smaller Pharmacies, Bigger Impact: Inside Manufacturers’ Specialty Networks in 2025

Drug Channels

Last week, we examined the growing concentration of specialty drug dispensing revenues among the largest pharmacies. See The Top 15 Specialty Pharmacies of 2024: How PBMs, Health Systems, and Independents Are Shaping the Market. Today, we dive deeper. Drawing from DCIs new 2025 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers , we explore how pharmaceutical manufacturers structure their specialty pharmacy networksand how smaller, independent pharmacies have emerged as dominant pl