Mon.Jun 02, 2025

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Fluoride Ban Could Create Cavities For 1 Of Every 3 U.S. Kids

Drugs.com

MONDAY, June 2, 2025 Removing fluoride from the U.S. water supply could result in more than 25 million more decayed teeth in children and teenagers within five years, a new study warns.Thats the equivalent of a decayed tooth for 1 of every 3 kid.

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Bristol Myers allies with BioNTech on bispecific cancer drug

BioPharma Drive: Drug Pricing

The oncology giant will pay $1.5 billion to co-develop a BioNTech drug that targets the proteins PD1 and VEGF, following Merck, and Pfizer into what’s become a competitive development race.

Drugs 293
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Brain training game offers new hope for drug-free pain management

Science Daily: Pharmacology News

A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain -- offering hope for a new generation of drug-free treatments.

Drugs 299
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Vera drug scores in closely watched study in rare kidney disease

BioPharma Drive: Drug Pricing

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.

Disease 184
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Research shows how solar arrays can aid grasslands during drought

Science Daily: Pharmacology News

New research shows that the presence of solar panels in Colorado's grasslands may reduce water stress, improve soil moisture levels and -- particularly during dry years -- increase plant growth by about 20% or more compared to open fields.

Research 256
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Sanofi to acquire Blueprint for up to $9.5B

BioPharma Drive: Drug Pricing

The pharma giant is betting that Blueprint, whose research revolves around a certain kind of tyrosine kinase, will be a boost to its immunology business.

Research 157

More Trending

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Genetics is a missing link in kidney disease drug development

BioPharma Drive: Drug Pricing

Genetic research is driving progress in kidney disease drug discovery.

Disease 147
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Dads Help Shape Eating Habits of Their Children

Drugs.com

MONDAY, June 2, 2025 A dads eating habits can have a profound effect on their kids diets, even when those children are nothing but a twinkle in his eye, a new study says.Men who established a healthy diet as teens were more likely to model healt.

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Kymera, with new data, takes early step toward a Dupixent-like pill

BioPharma Drive: Drug Pricing

Phase 1 results disclosed Monday indicate the company’s protein-degrading drug can affect a tough-to-reach target called STAT6 that’s implicated in many autoimmune conditions.

Drugs 144
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Webb reveals the origin of the ultra-hot exoplanet WASP-121b

Science Daily: Pharmacology News

Tracing the origin of an ultra-hot exoplanet: The chemical composition of WASP-121b suggests that it formed in a cool zone of its natal disc, comparable to the region of gas and ice giants in our Solar System. Methane indicates unexpected atmospheric dynamics: Despite extreme heat, methane was detected on the nightside -- a finding that can be explained by strong vertical atmospheric circulation.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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The Dark Reality of Drug Patent Thickets: Innovation or Exploitation?

Drug Patent Watch

"The Patent Paradox: How Big Pharma's Web of Exclusivity is Suffocating Innovation As the world grapples with the rising costs of healthcare, a hidden culprit is quietly strangling the development of life-saving treatments: the 'patent thicket.' In a system designed to incentivize innovation, these complex webs of exclusive rights are instead fueling a culture of exploitation, where pharmaceutical giants use their patents to stifle competition and reap exorbitant profits.

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Precision medicine’s next frontier: unlocking the power of biospecimens

Fierce BioTech

In conversation with Fierce Biotechs Chris Hayden, Austin Read, head of PPD CorEvitas Precision Medicine, Thermo Fisher Scientific, unpacks the evolving landscape of precision therapeutic and di | Austin Read of Thermo Fisher Scientific discusses how combining biospecimens with real-world data is advancing diagnostics, treatment and the future of patient care.

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Deploying a Scalable Next.js App on Vercel – A Step-by-Step Guide

Perficient: Drug Development

In this era of Web development, Next.JS and Vercel is the powerful couple. Next.JS offers performance, scalability and flexibility in building web applications whereas Vercel provides the easy and smooth deployment experience tailored for it. Today, in this blog, we will cover the step-by-step process of deploying a Next.JS app on Vercel. We will also cover some best practices and key configurations to ensure the optimal performance in production.

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Strategic planning in ADC development: insights from Lonza

Drug Target Review

Bioconjugates are rapidly emerging as a key frontier in targeted therapies, particularly through Antibody-Drug Conjugates (ADCs) , which combine antibodies with cytotoxic drugs to deliver more precise and effective treatments. This fusion enables precise delivery of potent drugs directly to cancer cells or other targeted tissues, significantly improving the therapeutic impact while minimising harm to healthy cells.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Over The Air Updates for React Native Apps

Perficient: Drug Development

Mobile App development is rapidly growing and so is the expectation of robust support. “Mobile first” is the set paradigm for many application development teams. Unlike web deployment, an app release has to go through the review process via App Store Connect and Google Play. Minor or major releases follow the app review same process, which can take 1-4 days.

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FDA Abandons Its Defense of the LDT Rule, But is It Signaling an Increase in RUO Scrutiny?

FDA Law Blog: Biosimilars

By Steven J. Gonzalez & Allyson B. Mullen At midnight on Friday, May 30, 2025, the governments deadline to notice an appeal from the U.S. District Court for the Eastern District of Texass decision vacating the LDT Rule lapsed without the government doing so. This means the District Court decision stands, with no further right of appeal, and the LDT Rule remains vacated in its entirety.

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Kisspeptin‐54 Restores Blood–Brain Barrier Integrity via GATA‐4 in Ischemic Stroke

Chemical Biology and Drug Design

This study investigates the neuroprotective effects of Kisspeptin-54 in ischemic stroke. In mice with induced stroke, Kisspeptin-54 reduced brain damage, improved neurological function, and restored occludin levels, strengthening the bloodbrain barrier. The findings reveal that Kisspeptin-54 enhances endothelial resilience through GATA-4-driven occludin expression, suggesting a promising therapeutic approach for stroke treatment.

Treatment 100
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The Three Pillars of Getting Voice AI Right: Data, Design, and Deployment

Perficient: Drug Development

Customer Contact Week is just around the corner! In preparation, I sat down with our Senior Solutions Architect, Miles Phillips, to dive deeper into the key pillars of Voice AI: Data, Design, and Deployment. Miles provides insights on how businesses can optimize their AI strategies to enhance customer interactions and drive real results. Voice AI is no longer a futuristic concept, its quickly becoming a foundational technology in modern contact centers.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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The Eternal Life and Art of Maxwell Ardeen

Codon

The earliest painters worked as both chemists and materials scientists, discovering ways to combine natural pigments with fatty binders to yield vibrant paints. Renaissance painters moonlighted — quite literally — as anatomists. Leonardo da Vinci famously dissected some 30 corpses , in large part to aid in writing a treatise on painting , eventually compiling an understanding of human anatomy unequalled in his time.

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Conversational Commerce: Transforming Digital Shopping Through AI-Powered Conversations

Perficient: Drug Development

Although the traditional model has served us well, customers now have exceptionally high expectations for service in an eCommerce experience. Despite the complexity of building product catalogs, developing a headless frontend with top-tier UX, promotion engines, and segment-based personalization, customers still expect high-quality information delivered instantly, in a way that minimizes the time required to make a purchase.

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Dancing brainwaves: How sound reshapes your brain networks in real time

Science Daily: Pharmacology News

What happens inside your brain when you hear a steady rhythm or musical tone? According to a new study, your brain doesn't just hear it -- it reorganizes itself in real time.

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Beyond AEM: How Adobe Sensei Powers the Full Enterprise Experience

Perficient: Drug Development

In our previous post , we explored how Adobe Sensei and GenAI capabilities are already transforming content management through Adobe Experience Manager (AEM). But Sensei’s true value isnt limited to content operations, it’s the unified AI engine that quietly powers marketing intelligence, customer personalization, and even creative automation across Adobes enterprise ecosystem.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Bispecific competition, debating oral SERDs and a bold GLP-1 prediction

BioPharma Drive: Drug Pricing

Antibody drugs that target the PD-1 and VEGF pathways are in the ASCO spotlight, while doctors wrestle with how to use a new crop of breast cancer medicines.

Doctors 283
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Geological time capsule highlights Great Barrier Reef's resilience

Science Daily: Pharmacology News

New research adds to our understanding of how rapidly rising sea levels due to climate change foreshadow the end of the Great Barrier Reef as we know it. The findings suggest the reef can withstand rising sea levels in isolation but is vulnerable to associated environmental stressors arising from global climate change.

Research 253
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Eating Healthier Can Protect Aging Brain

Drugs.com

MONDAY, June 2, 2025 Its never too late to start eating right as a means of protecting your brain health, a new study says.People who improved their healthy eating in middle-age had a 25% lower risk of lower risk of dementia, compared to those wh.

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Attachment theory: A new lens for understanding human-AI relationships

Science Daily: Pharmacology News

Human-AI interactions are well understood in terms of trust and companionship. However, the role of attachment and experiences in such relationships is not entirely clear. In a new breakthrough, researchers from Waseda University have devised a novel self-report scale and highlighted the concepts of attachment anxiety and avoidance toward AI. Their work is expected to serve as a guideline to further explore human-AI relationships and incorporate ethical considerations in AI design.

Research 249
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FDA Approves Tryptyr Eye Drops for Dry Eye Disease

Drugs.com

MONDAY, June 2, 2025 -- The U.S. Food and Drug Administration has approved the first-in-class TRPM8 receptor agonist Tryptyr (acoltremon ophthalmic solution) for the treatment of signs and symptoms of dry eye disease.Currently, dry eye disease.

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The sweet spot: sugar-based sensors to revolutionize snake venom detection

Science Daily: Pharmacology News

Researchers have published the first example of a synthetic sugar detection test for snake venom, offering a new route to rapid diagnosis and better antivenoms.

Research 248
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Cucumber-Linked Salmonella Outbreak Sickens Dozens Across 18 States

Drugs.com

MONDAY, June 2, 2025 A growing salmonella outbreak tied to cucumbers has made at least 45 people sick across 18 states, U.S. health officials have warned.The cucumbers came from Bedner Growers, a Florida-based company, and were distributed by F.

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Enhertu potential broadens as new data point to frontline breast cancer role

BioPharma Drive: Drug Pricing

Study results unveiled at ASCO show combining Enhertu with Perjeta can significantly delay tumor growth versus a regimen that's been standard treatment for more than a decade.

Treatment 144
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Exercise Cuts Colon Cancer Recurrence and Boosts Survival, Study Finds

Drugs.com

MONDAY, June 2, 2025 A structured exercise program helped colon cancer survivors live longer and lowered their odds for a relapse, a major international study shows.The program lasted three years and included regular meetings with a fitness c.

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A vision for the future of lung cancer treatment

BioPharma Drive: Drug Pricing

Precision medicine for lung cancer has evolved. But what about mutations that resist treatment?

Treatment 130