Fri.Jun 14, 2024

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New lab space for early-stage life science businesses

Drug Discovery World

Discovery Park has opened CoLab, a new shared lab facility in the UK. In partnership with Canterbury Christ Church University, CoLab has been designed for early-stage life science businesses, providing flexible bench space in a coworking environment. Dr Cornelia Wilson, Senior Lecturer and Academic Laboratory Director at Canterbury Christ Church University, said: “Finding lab space is too often a blocker for promising life science spin outs and start-ups, and CoLab exists to solve this.

Science 147
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Some CRISPR screens may be missing cancer drug targets

Broad Institute

Some CRISPR screens may be missing cancer drug targets By Allessandra DiCorato June 14, 2024 Breadcrumb Home Some CRISPR screens may be missing cancer drug targets Current CRISPR guides don’t work equally well in cells from people of all ancestries, which could lead to false negative results. By Allessandra DiCorato June 14, 2024 Credit: Ricardo Job-Reese, Broad Communications CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically t

Drugs 145
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Breakthrough drug discovery research collaboration in obesity

Drug Discovery World

Flagship Pioneering and ProFound Therapeutics have announced a collaboration to conduct foundational research to identify potential next-generation first-in-class therapies for the treatment of obesity. The collaboration is the first initiated under Flagship’s Pioneering Medicines strategic partnership with Pfizer announced in July 2023. Pioneering Medicines, Flagship’s in-house drug discovery and development unit, is responsible for leading the partnership with Pfizer, including driving the exp

Research 147
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FDA Tells Vaccine Makers to Target New COVID Variant for Fall

Drugs.com

FRIDAY, June 14, 2024 -- COVID vaccine makers will be advised to update their shots to target the KP.2 variant, an offshoot of the JN.1 variant that spread widely last winter, the U.S. Food and Drug Administration announced Thursday. It's a.

Vaccine 115
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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This week in drug discovery (10-14 June) 

Drug Discovery World

News round-up for 10-14 June by DDW Senior Digital Content Editor Diana Spencer. With a lead story on the restoration of congenital hearing loss following gene therapy, the news highlights selection this week focuses on cell and gene therapies (CGT) and genetics, particularly some key progress in relation to CAR-T therapies. The top stories: Gene therapy restores hearing in both ears Five children who were born with congenital hearing loss can hear in both ears after taking part in a gene therap

Therapies 130
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Tiny New Zealand bird delivers a lesson in birdsong evolution

Science Daily: Pharmacology News

Scientists are rethinking the evolution of vocal learning in birds. New Zealand's smallest bird, the rifleman or titipounamu, may have a rudimentary version of the talent possessed by parrots, hummingbirds and songbirds.

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Infectious H5N1 influenza virus in raw milk rapidly declines with heat treatment

Science Daily: Pharmacology News

The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry.

Virus 107
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Poll Finds Many Young Workers Feeling Stressed, Isolated

Drugs.com

FRIDAY, June 14, 2024 -- Many younger workers feel stressed, isolated and unappreciated at their jobs, a new survey has found. The 2022 Work in America survey, conducted by the American Psychological Association (APA), found that young adults are.

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Sharks have depleted functional diversity compared to the last 66 million years

Science Daily: Pharmacology News

New research has found that sharks retained high levels of functional diversity for most of the last 66 million years, before steadily declining over the last 10 million years to its lowest value in the present day.

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'Good Days and Bad:' Catherine, Princess of Wales, Gives Cancer Update

Drugs.com

FRIDAY, June 14, 2024 -- Catherine, Princess of Wales, has released the first update on her cancer journey since announcing her diagnosis in late March.In a message posted to her Instagram account on Friday, the princess, 42, said that, "I am.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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High-precision measurements challenge our understanding of Cepheids

Science Daily: Pharmacology News

Scientists have clocked the speed of Cepheid stars -- 'standard candles' that help us measure the size of the universe -- with unprecedented precision, offering exciting new insights about them.

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Even Temporary Loneliness Can Harm Physical Health

Drugs.com

THURSDAY, June 14, 2024 -- You don't consider yourself a lonely person generally, but sometimes have days where feelings of loneliness set in. If you're one of those people, even that transient loss of connection with others could be impacting your.

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Takeda circles a leukemia drug; J.P. Morgan moves into biotech investing

BioPharma Drive: Drug Pricing

The Japanese pharma paid $100 million to secure option rights to an Ascentage drug. Elsewhere, J.P. Morgan Private Capital closed its first fund and the FDA gave new COVID shot advice.

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Just 1 in 20 Animal Studies Yield Treatments That Make it to Humans

Drugs.com

FRIDAY, June 14, 2024 -- Animal studies are often considered a first step in finding new drugs and treatments for human diseases, but a new review has discovered that precious few actually produce real-world therapies. Only 5% of therapies tested.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Radiopharma drugmaker Telix pulls US IPO plans

BioPharma Drive: Drug Pricing

The Australia-based company had proposed raising $202 million via an initial stock sale, but withdrew its filing, citing its shares’ recent price appreciation on Australia’s stock exchange.

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GLP-1 Meds May Help Extremely Obese Qualify for Weight-Loss Surgery

Drugs.com

FRIDAY, June 14, 2024 -- Taking a cutting-edge weight-loss drug could help extremely obese patients drop enough pounds to be eligible for bariatric surgery, a new study shows. Patients with extreme obesity -- a BMI of 70 or more -- are at higher.

Drugs 98
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How AI Accelerates Clinical & Drug Development Timelines

Fierce BioTech

How AI Accelerates Clinical & Drug Development Timelines pesurya Fri, 06/14/2024 - 10:59 Wed, 09/11/2024 - 14:00 Resource Type Webinar Viswa Colluru, Ph.D. Tony Cardozo Todd Rudo, M.D. Beth Williams Duration 60 Minutes As the drug development landscape rapidly evolves, artificial intelligence (AI) is emerging as a transformative force, fundamentally reshaping processes and enhancing efficiencies.

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New Form of Psychotherapy Might Help Ease Chronic Pain

Drugs.com

FRIDAY, June 14, 2024 -- A new form of psychotherapy appears to work even better at treating chronic pain in older adults than gold-standard cognitive behavioral therapy (CBT), a new study finds. U.S. veterans who received emotional awareness and.

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3 PIM Analytics Tools to Drive More Sales

Perficient: Drug Development

Importance of Product Data in Driving Sales When you don’t have a storefront and a salesperson to do the talking, your product content has to be rich. So, your task is to reduce the uncertainty as much as possible. Remember, customers won’t always buy the better product; they prefer the product they better understand and can find. PIM Analytics can be important tool in your toolkit to make sure your product content is working as intended.

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Dolphins Off Florida, Georgia Have High Levels of Mercury

Drugs.com

THURSDAY, June 14, 2024 -- Dolphins living off the coasts of Georgia and Florida have elevated levels of mercury in their bodies, new research shows. That could have implications for people, said a team led by Colleen Bryan, a research biologist at.

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How Spatial Omics Is Unleashing the Potential of Regenerative Medicine

Fierce BioTech

How Spatial Omics Is Unleashing the Potential of Regenerative Medicine Spatial omics, the study of molecular profiles within their spatial context, is revolutionizing regenerative medicine by offering insights into tissue organization and disease pathology. Download this free whitepaper today which addresses why spatial omics is a key enabler of research that could transform lives. smarcus Fri, 06/14/2024 - 11:48 Spatial omics, the study of molecular profiles within their spatial context, is rev

Disease 52
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Loaded, Unlocked Guns Common in American Homes, Study Finds

Drugs.com

FRIDAY, June 14, 2024 -- In half of American homes containing a loaded gun, that gun is kept unsecured and ready for potential use, often with children in the home, new research shows. The finding is especially troubling given the link between gun.

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Usability and Experience (UX) in Universal Design Series: Impact on Diverse User Groups – 5

Perficient: Drug Development

Embracing Diversity: The Impact of Usability and UX on Diverse User Groups In this installment of our Usability and Experience (UX) in Universal Design series, we will explore the profound impact that usability and UX principles have on diverse user groups. Universal Design aims to create products, environments, and systems that are accessible and inclusive for everyone, regardless of their abilities, age, cultural background, or cognitive differences.

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Animal Studies Suggest New Treatment Target for Spinal Cord Injury

Drugs.com

FRIDAY, June 14, 2024 -- Spinal cord injuries can cause the body to go haywire, with misfiring nerves causing dangerous “fight-or-flight” responses. This makes typical and normally harmless problems like having a full bladder prompt.

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AbbVie joins in latest gastrointestinal drug chase

BioPharma Drive: Drug Pricing

Following Roche, Merck and others into a hot field, the Humira maker will pay $150 million to license a preclinical TL1A antibody for IBD.

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Swimming 'Microbots' Could Speed Meds to Lung Tumors, Early Study Suggests

Drugs.com

FRIDAY, June 14, 2024 -- Scientists have developed microscopic robots capable of swimming through the lungs to deliver chemotherapy directly to lung cancer cells. In early testing, these microbots extended the average survival time of lab mice.

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Getting to the Heart of Science with Sophie Dubois

Alta Sciences

Getting to the Heart of Science with Sophie Dubois blussier Fri, 06/14/2024 - 21:16 HTML The Stories That Inspire In this video, our very own Sophie Dubois shares what led her to Altasciences and how the company’s core values and mission of helping to improve lives resonate with her. Image Getting_to_the_Heart_of_Science_With_Sophie_Dubois.

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The Regulatory Binder Checklist For Clinical Trial Sites

Advarra

A regulatory binder is essential for managing clinical trial documents, ensuring regulatory compliance, and facilitating audits. It organizes critical documents; provides easy access for trial monitors, auditors, and regulatory authorities; and serves as a reference for the research team. Though not legally binding, maintaining a regulatory binder is highly recommended for all intervention trials.

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Which pharmaceutical drugs have the most drug patents in Bulgaria?

Drug Patent Watch

This chart shows the drugs with the most patents in Bulgaria. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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CAR-T therapy successfully targets advanced prostate cancer

Drug Discovery World

A team of investigators at City of Hope in the US funded by the Prostate Cancer Foundation (PCF) reports that patients with advanced prostate cancer can be safely treated with chimeric antigen receptor (CAR)-T cell therapy. The results of their first-in-human Phase I clinical trial, which also showed promising therapeutic activity, were published in Nature Medicine.

Therapies 147