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Psychology literature has shown that curiosity tends to decline with age. Psychologists shows one type of curiosity can increase well into old age, contradicting prior research. Older adults who maintain curiosity and want to learn new things relevant to their interests may be able to offset or even prevent Alzheimer's disease. Conversely, those who show muted curiosity and disinterest may be at risk for dementia.
Xinyuan Wu, Jiayi Pan, Rufeng Fan, Yiwei Zhang, Chao Wang, Guoliang Wang, Jiaxiang Liu, Mengqing Cui, Jinfeng Yue, Rui Jin, Zhiqiang Duan, Mingyue Zheng, Lianghe Mei, Lu Zhou, Minjia Tan, Jing Ai, and Xiaojie Lu Journal of the American Chemical Society 2025 147 (18), 15469-15481 DOI: 10.1021/jacs.5c01712 Covalent small molecule drugs have emerged as a crucial support in precision therapy due to their high selectivity and robust potency.
Researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior.
Novo Nordisk Foundation Center for Genomic Mechanisms of Disease: Building a scientific bridge By Rose Circeo May 7, 2025 Breadcrumb Home Novo Nordisk Foundation Center for Genomic Mechanisms of Disease: Building a scientific bridge Type 2 diabetes impacts millions around the world, and yet its root cause remains a mysterya challenge the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease (NNFC) at the Broad Institute is tackling by bringing together Denmark-based and Broad scientis
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
People who eat more ultra processed foods like cold breakfast cereal, cookies and hot dogs are more likely to have early signs of Parkinson's disease when compared to those who eat very few ultra processed foods, according to a new study. The study does not prove that eating more ultra processed foods causes early signs of Parkinson's disease; it only shows an association.
WEDNESDAY, May 7, 2025 The shingles vaccine has benefits that stretch beyond protecting older adults from the painful skin condition, a new study says.Folks who get the shingles jab have a 23% lower risk of health problems like stroke, heart f.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
WEDNESDAY, May 7, 2025 The shingles vaccine has benefits that stretch beyond protecting older adults from the painful skin condition, a new study says.Folks who get the shingles jab have a 23% lower risk of health problems like stroke, heart f.
Engineers have invented a sponge-like device that captures water from thin air and then releases it in a cup using the sun's energy, even in low humidity where other technologies such as fog harvesting and radiative cooling have struggled. The water-from-air device remained effective across a broad range of humidity levels (30 -- 90%) and temperatures (5 -- 55 degrees Celsius).
WEDNESDAY, May 7, 2025 Stress can make it even worse for people to deal with chronic obstructive pulmonary disease, or COPD, a new study says.High levels of perceived stress are associated with a quadrupled risk of moderate or severe COPD f.
Across the globe, monsoon rainfall switches on in spring and off in autumn. Until now, this seasonal pattern was primarily understood as an immediate response to changes in solar radiation. A new study shows that the atmosphere can store moisture over extended periods, creating a physical memory effect. It allows monsoon systems to flip between two stable states.
WEDNESDAY, May 7, 2025 What your child eats could play a role in when they start puberty, a new study shows.Researchers found that girls who ate more inflammatory foods were 15% more likely to get their first period in the next month. On the o.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
In a sweeping new study of more than 13,000 urban areas worldwide, researchers have mapped air pollution levels and carbon dioxide emissions, providing comprehensive global analysis of urban environmental quality.
WEDNESDAY, May 7, 2025 -- Conversion therapy might harm a young persons long-term heart health, a new study says.Young adults assigned male at birth were nearly three times as likely to be diagnosed with high blood pressure if theyd been exposed t.
Wealthy individuals have a higher carbon footprint. A new study quantifies the climate outcomes of these inequalities. It finds that the world's wealthiest 10% are responsible for two thirds of observed global warming since 1990 and the resulting increases in climate extremes such as heatwaves and droughts.
WEDNESDAY, May 7, 2025 The official in charge of federal food and drug safety inspections will retire May 14.Michael Rogers, associate commissioner for inspections and investigations at the U.S. Food and Drug Administration (FDA), announced his d.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Climate scientists reveal that millions of today's young people will live through unprecedented lifetime exposure to heatwaves, crop failures, river floods, droughts, wildfires and tropical storms under current climate policies. If global temperatures rise by 3.5 C by 2100, 92% of children born in 2020 will experience unprecedented heatwave exposure over their lifetime, affecting 111 million children.
WEDNESDAY, May 7, 2025 The U.S. Food and Drug Administration (FDA) has chosen Dr. Vinay Prasad, a professor at the University of California-San Francisco, to lead its Center for Biologics Evaluation and Research.The division oversees vaccines and.
A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed. This crucial advance in the fight against metastatic cancer is based on identifying the cellular site for ferroptosis initiation, a natural process, catalyzed by iron, that sparks the oxidative degradation of cell membranes.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Bacterial resistance negates the effect of antibiotics in the treatment of infection. Using mouse models, researchers now show that if antibiotics are administered with an enzyme called endolysin, the combined effect protects against infection by resistant bacteria in all bodily organs -- including the brain, which antibiotics alone have difficulty reaching.
WEDNESDAY, May 7, 2025 -- The prevalence of depressive symptoms increased among U.S. adults during the pandemic, according to a research letter published online May 5 in JAMA Internal Medicine.Kosuke Inoue, M.D., Ph.D., from the Beth Israel.
Newly discovered species of extinct fish shows striking similarities to unrelated modern-day predators, suggesting certain traits have emerged multiple times and remained consistent over hundreds of millions of years.
WEDNESDAY, May 7, 2025 -- Persistently high blood sugar among teenagers can lead to heart disease by young adulthood, a new study says.Teenagers had up to three times the risk of developing a heart condition called left ventricular hypertrophy if.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
A landmark study exploring consumption of chips, frozen pizzas, breakfast cereals and other ultra-processed foods typically loaded with fat, sugar and additives has confirmed these foods are directly and significantly linked to poor health outcomes.
WEDNESDAY, May 7, 2025 -- The use of nicotine pouches nearly doubled among U.S. high school students between 2023 and 2024, a new study says.These pouches, inserted between the gum and lip, provide teenagers an opportunity to use nicotine in a.
Magnetar flares, colossal cosmic explosions, may be directly responsible for the creation and distribution of heavy elements across the universe, suggests a new study.
"The Patent Box Tax Incentive: A Game-Changer for Pharmaceutical Innovation? As the pharmaceutical industry continues to drive groundbreaking research and development, a lesser-known tax incentive has emerged as a key catalyst for innovation. The Patent Box tax regime, introduced in the UK in 2013, has been hailed as a success in fostering a culture of R&D and entrepreneurship.
Brain researchers have identified a bridge between the thalamus and the cortex as the key area that is modified during motor learning functions. They found that such learning does much more than adjust activity levels, it sculpts the circuit's wiring, refining the conversation between brain regions.
How the Novo Nordisk Foundation Center at Broad is using scalable technologies and AI to find the root cause of diabetes By Corie Lok May 7, 2025 Breadcrumb Home How the Novo Nordisk Foundation Center at Broad is using scalable technologies and AI to find the root cause of diabetes Broad and Denmark-based scientists are collaborating to scale up their efforts to turn genetic insights into the fundamental biological mechanisms underlying metabolic disease.
Physicists captured the first images of individual atoms freely interacting in space. The pictures reveal correlations among the 'free-range' particles that until now were predicted but never directly observed.
ELRIG Announces Keynote Speakers for Drug Discovery 2025 Prof Heather Pinkett and Dr Dafydd Owen to lead ELRIGs flagship event Drug Discovery returns to Liverpool, 2122 October 2025 to celebrate A Festival of Life Science Event supported by VisitBritain showcases UK life science sector and extends international reach Cambridge, UK, 07 May 2025: ELRIG, a not-for-profit, volunteer-led organisation dedicated to the global drug discovery community, has revealed the keynote speakers for its flagship
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