Fri.Sep 22, 2023

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Scientists Spot Gene Mutation Linked to Esophageal Cancer

Drugs.com

FRIDAY, Sept. 22, 2023 -- Researchers have found a gene mutation linked to esophageal cancer, which could lead to better prevention and treatment strategies. Investigators from Case Western Reserve University in Ohio found the mutation, potentially.

Treatment 299
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Jellyfish, with no central brain, shown to learn from past experience

Science Daily: Pharmacology News

Even without a central brain, jellyfish can learn from past experiences like humans, mice, and flies, scientists report for the first time. They trained Caribbean box jellyfish (Tripedalia cystophora) to learn to spot and dodge obstacles. The study challenges previous notions that advanced learning requires a centralized brain and sheds light on the evolutionary roots of learning and memory.

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Newer Diabetes Meds Might Not Work as Well in Black Patients

Drugs.com

FRIDAY, Sept. 22, 2023 – New research suggests some newer diabetes treatments may not be as beneficial for Black patients, after earlier drug trials included small numbers of non-white people. Whether the medications -- called sodium-glucose.

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Astronomers find abundance of Milky Way-like Galaxies in early Universe, rewriting cosmic evolution theories

Science Daily: Pharmacology News

Galaxies from the early Universe are more like our own Milky Way than previously thought, flipping the entire narrative of how scientists think about structure formation in the Universe, according to new research.

Research 268
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Kraft Cheese Slices Recalled Due to Plastic Wrap Choking Hazard

Drugs.com

FRIDAY, Sept. 22, 2023 -- Kraft Heinz said it is recalling over 83,000 packs of its Kraft Singles American processed cheese slices because of a packaging defect in the plastic that wraps the cheese slices. A temporary issue developed on one of the.

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Medicaid Reinstated for Nearly 500,000 Children and Families: CMS

Drugs.com

FRIDAY, Sept. 22, 2023 – About 500,000 children and families have had their Medicaid reinstated after some states erroneously purged them because of a systems issue, the U.S. Centers for Medicare and Medicaid (CMS) said Thursday. The agency had.

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Pollen analysis suggests peopling of Siberia and Europe by modern humans occurred during a major Pleistocene warming spell

Science Daily: Pharmacology News

A new study appearing in Science Advances compares Pleistocene vegetation communities around Lake Baikal in Siberia, Russia, to the oldest archeological traces of Homo sapiens in the region. The researchers use the 'remarkable evidence' to tell a compelling story from 45,000-50,000 years ago with new detail: how the first humans migrated across Europe and Asia.

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In 22 U.S. States, More Than a Third of Adults Are Now Obese

Drugs.com

FRIDAY, Sept. 22, 2023 -- Obesity is on the rise across the United States. In 22 states, 35% of adults or more were obese last year, new data from the U.S. Centers for Disease Control and Prevention show. Just 10 years ago, there were no states that.

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Astronomers discover newborn galaxies with the James Webb Space Telescope

Science Daily: Pharmacology News

With the launch of the James Webb Space Telescope, astronomers are now able to peer so far back in time that we are approaching the epoch where we think that the first galaxies were created. Throughout most of the history of the Universe, galaxies seemingly tend to follow a tight relation between how many stars they have formed, and how many heavy elements they have formed.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Vaping Raises a Teen's Odds of Developing Asthma

Drugs.com

FRIDAY, Sept. 22, 2023 -- New research underscores the harms of e-cigarettes, showing that vaping increases the risk of asthma in teens who have never smoked cigarettes. Although e-cigarettes have fewer toxins than regular cigarettes, they still.

Research 223
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Why are you better at recognizing upright faces? Clues from a person who sees the world differently

Science Daily: Pharmacology News

When you see a familiar face upright, you'll recognize it right away. But if you saw that same face upside down, it's much harder to place. Now researchers who've studied Claudio, a 42-year-old man whose head is rotated back almost 180 degrees such that it sits between his shoulder blades, suggest that the reason people are so good at processing upright faces has arisen through a combination of evolution and experience.

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RSV Vaccine Given in Pregnancy to Help Shield Newborns Receives Full U.S. Approval

Drugs.com

FRIDAY, Sept. 22, 2023 -- Women may soon have a vaccine they can take during a pregnancy to help protect their newborn from respiratory syncytial virus (RSV). Following approval one month ago by the U.S. Food and Drug Administration, the Centers for.

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Carbon source found on surface of Jupiter's moon Europa

Science Daily: Pharmacology News

Astronomers using data from NASA's James Webb Space Telescope have identified carbon dioxide in a specific region on the icy surface of Europa.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Kids' ER Visits for Mental Health Crises Rise When School Term Begins

Drugs.com

FRIDAY, Sept. 22, 2023 -- While the start of the school year can give kids and teens the chance to reconnect with friends and enjoy school sports and activities, it can also trigger stressors that send many to the emergency room for mental health.

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AstraZeneca and Daiichi’s next cancer medicine scores in breast tumors

BioPharma Drive: Drug Pricing

Results show that the medicine helped patients who progressed on earlier-line treatments live longer than those receiving chemotherapy without their disease getting worse, according to a Friday announcement.

Treatment 176
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Brain Trauma Could Help Trigger Heart Troubles

Drugs.com

FRIDAY, Sept. 22, 2023 -- While the neurological impact of a traumatic brain injury (TBI) has long been studied, new research suggests TBIs are also hard on the heart.

Research 162
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Latest trial win further supports expanded use of Bristol Myers’ Opdivo in lung cancer

BioPharma Drive: Drug Pricing

The drug, which is already cleared as a neoadjuvant lung cancer treatment, could further compete with Merck’s Keytruda if it gains approval in the adjuvant setting for patients with the non-small cell form of the disease.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Probing the deep genetic structure of Africa

Science Daily: Pharmacology News

Using ancestry decomposition techniques an international research team has revealed a deeply divergent ancestry among admixed populations from the Angolan Namib desert. This unique genetic heritage brings the researchers closer to understanding the distribution of genetic variation in the broader region of southern Africa before the spread of food production.

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Seagen’s cancer drug succeeds in ‘must-win’ trial

BioPharma Drive: Drug Pricing

Compared to chemotherapy, a combination of Seagen’s Padcev and Merck’s Keytruda was significantly better at keeping bladder cancer patients alive longer and their disease from progressing.

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9 common misconceptions about clinical trial participation

Antidote

Connecting patients with clinical research opportunities is our mission here at Antidote, but often, we find that misconceptions can serve as barriers to achieving this goal. It’s important to carefully weigh the pros and cons of participating in a clinical trial but to do this effectively, it’s critical to have accurate information.

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How organoids can redefine pre-clinical research

Drug Target Review

Organoid technologies are becoming an invaluable solution for preclinical research, with the ability to augment the development of personalised medicine, drug discovery and gene therapies. These 3D cultured structures that are derived from healthy individuals or patients’ cells, such as human pluripotent stem cells (hPSCs) 1 or adult stem cells (ADSCs) 2 are changing the paradigm of scientific understanding.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Novel Tank Diving Test with Zebrafish

biobide

Zebrafish ( Danio rerio ) has been used as a New Alternative Model (NAM) for the last 40 years. This organism conserves approximately 70% of gene homology with humans, in addition to having the benefit of possessing fast development, high fecundity, feasible maintenance, and ease of manipulation. This NAM complies with the 3Rs principle (Replacement, Reduction and Refinement), since it is possible to perform multiple assays on embryos.

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A Clear Path to Education Affordability Requires Meeting Patients Where They Are

Drug Channels

Today’s guest post comes from Kristina Crockett, VP of Product Management at CoverMyMeds. Kristina shares the story of a patient who cut pills in half to extend her prescriptions. Unfortunately, this patient didn’t know about manufacturer affordability programs. In this article, Kristina reviews how brands can help patients make connections that address medication affordability challenges, whether at the prescriber’s office, the pharmacy, or at home.

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Myth Busting: Master Protocol Edition

Cytel

Interest and appetite for master protocols is growing as sponsors consider opportunities in various therapeutic areas beyond oncology. During initial discussions, most quickly recognize the potential operational and inferential benefits of a master protocol; however, as sponsors dive deeper into the details, doubt creeps in and there are a multitude of reasons expressed for not moving forward with a master protocol.

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A Clear Path to Medication Affordability Requires Meeting Patients Where They Are

Drug Channels

Today’s guest post comes from Kristina Crockett, VP of Product Management at CoverMyMeds. Kristina shares the story of a patient who cut pills in half to extend her prescriptions. Unfortunately, this patient didn’t know about manufacturer affordability programs. In this article, Kristina reviews how brands can help patients make connections that address medication affordability challenges, whether at the prescriber’s office, the pharmacy, or at home.

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Which pharmaceutical companies have the most drug patents in China?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in China. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in China? appeared first on DrugPatentWatch - Make Better Decisions.

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Analysis Life Sciences: In new guidance, FDA outlines seven sources of confirmatory evidence to support single clinical studies

Agency IQ

In new guidance, FDA outlines seven sources of confirmatory evidence to support single clinical studies The FDA has just released a long-anticipated draft guidance giving sponsors practical information on when and how to leverage confirmatory evidence to support a drug that is seeking approval using a single adequate, well-controlled clinical study to demonstrate effectiveness in lieu of additional clinical evidence.

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New patent for Mallinckrodt Ard drug ACTHAR GEL

Drug Patent Watch

Annual Drug Patent Expirations for ACTHAR+GEL Acthar Gel is a drug marketed by Mallinckrodt Ard and is included in one NDA. It is available from one supplier. The generic ingredient… The post New patent for Mallinckrodt Ard drug ACTHAR GEL appeared first on DrugPatentWatch - Make Better Decisions.

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Article FDA: Following a 2018 draft framework, FDA unveils long-awaited PDURS draft guidance

Agency IQ

Following a 2018 draft framework, FDA unveils long-awaited PDURS draft guidance A long-awaited draft guidance on Prescription Drug Use-Related Software (PDURS) outlines when information from digital health tools could be represented on prescription drug labeling. Per the new draft guidance, key considerations include where the software gets its data inputs and what the expected benefit of the tool’s use could be.

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