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A research team has discovered a surprising phenomenon that could revolutionize how we think about signal amplification. Just two tiny vibrating units can, when connected with a delay, amplify their combined vibrations by 100 million times. Their findings have applications for communication technology, suggesting that small, simple devices could be used to transmit clear signals over long distances.
Pirtobrutinib CAS 2101700-15-4 JAYPIRCA RXC-005 LY3527727 LOXO-305 WHO 11681 WeightAverage: 479.436 Monoisotopic: 479.158052208 Chemical FormulaC 22 H 21 F 4 N 5 O 3 5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2 S )-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide FDA 2023, 1/27/2023, Jaypirca To treat relapsed or refractory mantle cell lymphoma in adults who have had at least two lines of systemic therapy, including a BTK inhibitor Drug Trials Snapshot Pirtobrutinib , so
A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the authors of the study asked the AI to design synthetic fragments which activate a gene coding for a fluorescent protein in some cells while leaving gene expression patterns unaltered.
Across hundreds of published papers, CBER’s new chief has argued for more stringent measures of assessing drugs for cancer and rare diseases, suggesting he might push for higher standards in the review of medicines under his division's purview.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Consumption of ultra-processed foods, such as sugar-sweetened beverages, potato chips and packaged cookies, may be associated with adverse health outcomes. Study finds each additional 100 grams/day consumption of ultra-processed foods increased risk of hypertension, cardiovascular events, cancer and more.
Vor Bio, Korro Bio, Insitro and Rallybio revealed plans to lay off chunks of their respective workforces in the latest job cuts for a sector struggling to hold its financial footing.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Vor Bio, Korro Bio, Insitro and Rallybio revealed plans to lay off chunks of their respective workforces in the latest job cuts for a sector struggling to hold its financial footing.
A new study of the 28 most populous U.S. cities finds that all are sinking to one degree or another. The cities include not just those on the coasts, where relative sea level is a concern, but many in the interior. Furthermore, using newly granular data, the study finds that some cities are sinking at different rates in different spots, or sinking in some places and rising in others, potentially introducing stresses that could affect buildings and other infrastructure.
THURSDAY, May 8, 2025 -- Fast food and ready-made packaged eats could be doing slow damage to peoples brains.Ultra-processed foods like breakfast cereals, soft drinks, hot dogs and ketchup appear to increase a persons risk of developing Par.
New technique for cell or drug delivery, localization of bioelectric materials, and wound healing uses ultrasound to activate printing within the body.
THURSDAY, May 8, 2025 A new drug combo lowers "bad" LDL cholesterol for people whose levels remain high even after taking statins.The new pill pairs a new drug called obicetrapib with an existing one, ezetimibe. In a Phase 3 clinical trial, this c.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Researchers developed FaceAge, an AI tool that calculate's a patient biological age from a photo of their face. In a new study, the researchers tied FaceAge results to health outcomes in people with cancer: When FaceAge estimated a younger age than a cancer patient's chronological age, the patient did significantly better after cancer treatment, whereas patients with older FaceAge estimates had worse survival outcomes.
THURSDAY, May 8, 2025 -- North Dakota is the latest state to find itself dealing with a measles outbreak, becoming the 11th state in the nation to face the challenge, the Associated Press is reporting.According to the North Dakota Department of.
An edible robot leverages a combination of biodegradable fuel and surface tension to zip around the water's surface, creating a safe -- and nutritious -- alternative to environmental monitoring devices made from artificial polymers and electronics.
The startup’s first prospect is a heart medicine that works differently than the hypertrophic cardiomyopathy drugs developed by Bristol Myers and Cytokinetics.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Why do cats generally live longer than dogs? New research suggests that longer lifespans of mammals like cats could be linked to their bigger brains and more complex immune systems.
A version of meloxicam designed to work faster has beat out a placebo in two late-stage studies focused on post-surgical acute pain. Viatris now plans to file for approval this year.
Scientists have launched an interactive global map to show the migratory patterns of more than 100 marine species in an effort to protect at-risk wildlife.
Ludovica S. Sirocchi, Maximilian Scharnweber, Sarah Oberndorfer, Gabriella Siszler, Krzysztof M. Zak, Klaus Rumpel, Ralph A. Neumller, and Birgit Wilding Journal of the American Chemical Society 2025 147 (18), 15787-15795 DOI: 10.1021/jacs.5c03562 Targeted covalent inhibitors are known to be successful therapeutics used in various indications. Covalent drugs typically target cysteine, as cysteine is well suited due to its high nucleophilicity.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Engineers developed a ping-pong-playing robot that quickly estimates the speed and trajectory of an incoming ball and precisely hits it to a desired location on the table.
THURSDAY, May 8, 2025 -- Sleep apnea could be costing you brain power and increasing your risk of dementia and Alzheimers disease, a new study says.The drop in blood oxygen levels that occurs during a sleep apnea episode appears to be linked to d.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
THURSDAY, May 8, 2025 -- People with Down syndrome have a much higher risk of stroke than people without the genetic disorder, a new study says.Down syndrome patients have a 5.14 times higher risk of a stroke caused by a brain bleed, and more than.
Mercury is released by environmental and human-driven processes. And some forms, specifically methylmercury, are toxic to humans. Therefore, policies and regulations to limit mercury emissions have been implemented across the globe. And, according to new research, those efforts may be working. Researchers found that atmospheric mercury levels have decreased by almost 70% in the last 20 years, mainly because human-caused emissions have been reduced.
THURSDAY, May 8, 2025 Wearing a face mask to protect others from infectious disease continues to be hotly debated in the United States.But what about wearing a face mask to detect chronic kidney disease?A modified surgical face mask containing a s.
Augmented-reality (AR) technology is rapidly finding its way into everyday life, from education and healthcare to gaming and entertainment. However, the core AR device remains bulky and heavy, making prolonged wear uncomfortable. A breakthrough now promises to change that. A research team has slashed both thickness and weight using a single-layer waveguide.
The company added to a recent flurry of pledges by pharmaceutical companies, promising $11 billion in new capital and operational investments in U.S. drug manufacturing.
A long period of drought in North America has been recognized by scientists for decades. A new study links the severe climate to a change in Earth's orbit.
THURSDAY, May 8, 2025 -- Some men would rather skip screening for prostate cancer due to fears that theyll be rendered impotent or incontinent from cancer surgery.But new research says those fears are unwarranted, thanks to improvements in the way.
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