July, 2024

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Virus that causes COVID-19 is widespread in wildlife, scientists find

Science Daily: Pharmacology News

SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species.

Virus 360
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Pfizer quits Duchenne gene therapy, lays off staff following study setback

BioPharma Drive: Drug Pricing

The company is letting go of 150 staffers alongside a decision to officially terminate the high-profile program, which was acquired in 2016.

Therapies 339
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Study Finds Big Shift in Who's Using GLP-1 Meds Like Ozempic

Drugs.com

TUESDAY, July 23, 2024 -- The boom in using GLP-1 drugs like Ozempic to treat obesity has resulted in a bust regarding the drugs’ original purpose, which was to treat type 2 diabetes, a new study finds. New prescriptions for these drugs have d.

Drugs 299
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Drug Discovery Industry Roundup with Barry Bunin — July, 22 2024

Collaborative Drug

How A.I. Is Revolutionizing Drug Development. Holy Grail for Weight-Loss Drugs Is Sleep Apnea? DNA Discovery that Could Help Find Pancreatic Cancer Cure.

DNA 263
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Generation X and millennials in US have higher risk of developing 17 cancers compared to older generations

Science Daily: Pharmacology News

A new large study suggests incidence rates continued to rise in successively younger generations in 17 of the 34 cancer types, including breast, pancreatic, and gastric cancers. Mortality trends also increased in conjunction with the incidence of liver (female only), uterine corpus, gallbladder, testicular, and colorectal cancers.

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New and improved camera inspired by the human eye

Science Daily: Pharmacology News

Computer scientists have invented a camera mechanism that improves how robots see and react to the world around them. Inspired by how the human eye works, their innovative camera system mimics the tiny involuntary movements used by the eye to maintain clear and stable vision over time.

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Ant insights lead to robot navigation breakthrough

Science Daily: Pharmacology News

Have you ever wondered how insects are able to go so far beyond their home and still find their way? The answer to this question is not only relevant to biology but also to making the AI for tiny, autonomous robots. Drone-researchers felt inspired by biological findings on how ants visually recognize their environment and combine it with counting their steps in order to get safely back home.

Research 355
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Researchers develop state-of-the-art device to make artificial intelligence more energy efficient

Science Daily: Pharmacology News

Engineering researchers have demonstrated a state-of-the-art hardware device that could reduce energy consumption for artificial intelligent (AI) computing applications by a factor of at least 1,000.

Research 349
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Scientists assess how large dinosaurs could really get

Science Daily: Pharmacology News

A study looks at the maximum possible sizes of dinosaurs, using the carnivore, Tyrannosaurus rex, as an example. Using computer modelling, experts produced estimates that T. Rex might have been 70% heavier than what the fossil evidence suggests.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Breaking MAD: Generative AI could break the internet, researchers find

Science Daily: Pharmacology News

Researchers have found that training successive generations of generative artificial intelligence models on synthetic data gives rise to self-consuming feedback loops.

Research 345
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Evidence for butchery of giant armadillo-like mammals in Argentina 21,000 years ago

Science Daily: Pharmacology News

Cut marks on fossils could be evidence of humans exploiting large mammals in Argentina more than 20,000 years ago, according to a new study.

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Scientists discover new T cells and genes related to immune disorders

Science Daily: Pharmacology News

Researchers have discovered several rare types of helper T cells that are associated with immune disorders such as multiple sclerosis, rheumatoid arthritis, and even asthma. The discoveries were made possible by a newly developed technology they call ReapTEC. The new T cell atlas is publicly available and should help in the development of new drug therapies for immune-mediated diseases.

Therapies 345
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Brain-imaging study reveals curiosity as it emerges

Science Daily: Pharmacology News

You look up into the clear blue sky and see something you can't quite identify. Is it a balloon? A plane? A UFO? You're curious, right? A research team has for the first time witnessed what is happening in the human brain when feelings of curiosity like this arise. The scientists revealed brain areas that appear to assess the degree of uncertainty in visually ambiguous situations, giving rise to subjective feelings of curiosity.

Research 345
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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A new twist on artificial 'muscles' for safer, softer robots

Science Daily: Pharmacology News

Engineers have developed a new soft, flexible device that makes robots move by expanding and contracting -- just like a human muscle. To demonstrate their new device, called an actuator, the researchers used it to create a cylindrical, worm-like soft robot and an artificial bicep. In experiments, the cylindrical soft robot navigated the tight, hairpin curves of a narrow pipe-like environment, and the bicep was able to lift a 500-gram weight 5,000 times in a row without failing.

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New drug shows promise in clearing HIV from brain

Science Daily: Pharmacology News

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.

Virus 342
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Giant salamander-like creature was a top predator in the ice age before the dinosaurs

Science Daily: Pharmacology News

Meet Gaiasia jennyae, the swamp creature with a toilet seat-shaped head. It lived 40 million years before the first dinosaurs, and it was the top predator in its ecosystem.

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Extinct humans survived on the Tibetan plateau for 160,000 years

Science Daily: Pharmacology News

Bone remains found in a Tibetan cave 3,280 m above sea level indicate an ancient group of humans survived here for many millennia.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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First local extinction in the US due to sea level rise, study suggests

Science Daily: Pharmacology News

The United States has lost its only stand of the massive Key Largo tree cactus in what researchers believe is the first local extinction of a species caused by sea level rise in the country.

Research 339
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Lilly drug for Alzheimer’s approved by FDA

BioPharma Drive: Drug Pricing

The drug, which Lilly will sell as Kinsunla, carries a warning for the risk of a certain kind of imaging abnormality that can be serious in rare cases.

FDA 339
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10 clinical trials to watch in the second half of 2024

BioPharma Drive: Drug Pricing

Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.

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An ant that selectively amputates the infected limbs of wounded sisters

Science Daily: Pharmacology News

Saving lives through surgery is no longer exclusive to humans. Scientists now detail how Florida carpenter ants, a common, brown species native to its namesake, selectively treat the wounded limbs of fellow nestmates -- either by wound cleaning or amputation. When experimentally testing the effectiveness of these 'treatments,' not only did they aid in recovery, but the research team found the ants' choice of care catered to the type of injury presented to them.

Treatment 338
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Breakthrough in skeletal muscle regeneration

Science Daily: Pharmacology News

In a finding that opens the door to the development of targeted therapies for various muscle disorders, newly published research identifies key mechanisms of skeletal muscle regeneration and growth of muscles following resistance exercise.

Therapies 336
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New geological datings place the first European hominids in the south of the Iberian Peninsula 1.3 million years ago

Science Daily: Pharmacology News

One of the most important controversies about human evolution and expansion is when and by what route the first hominids arrived in Europe from the African continent. Now, geological dating techniques at the Orce sites (Baza basin, Granada, Spain) place the human remains found in this area as the oldest in Europe, at approximately 1.3 million years old.

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Smell of human stress affects dogs' emotions leading them to make more pessimistic choices

Science Daily: Pharmacology News

Dogs experience emotional contagion from the smell of human stress, leading them to make more 'pessimistic' choices, new research finds. Researchers tested how human stress odors affect dogs' learning and emotional state.

Research 334
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Chimpanzees gesture back and forth quickly like in human conversations

Science Daily: Pharmacology News

When people are having a conversation, they rapidly take turns speaking and sometimes even interrupt. Now, researchers who have collected the largest ever dataset of chimpanzee 'conversations' have found that they communicate back and forth using gestures following the same rapid-fire pattern.

Research 334
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Psilocybin generates psychedelic experience by disrupting brain network

Science Daily: Pharmacology News

Researchers report that psilocybin, the active ingredient in magic mushrooms, destabilizes a critical network of brain areas involved in introspective thinking. The findings provide a neurobiological explanation for the drug's mind-bending effects.

Research 334
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A recipe for zero-emissions fuel: Soda cans, seawater, and caffeine

Science Daily: Pharmacology News

Engineers discovered that when the aluminum in soda cans is purified and mixed with seawater, the solution produces hydrogen -- which can power an engine or fuel cell without generating carbon emissions. The reaction can be sped up by adding caffeine.

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Scientists discover a cause of lupus and a possible way to reverse it

Science Daily: Pharmacology News

Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect may potentially reverse the disease.

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Waste Styrofoam can now be converted into polymers for electronics

Science Daily: Pharmacology News

A new study describes a chemical reaction that can convert Styrofoam into a high-value conducting polymer known as PEDOT:PSS. Researchers also noted that the upgraded plastic waste can be successfully incorporated into functional electronic devices, including silicon-based hybrid solar cells and organic electrochemical transistors.

Research 333