The Premier Consulting Blog
APRIL 13, 2025
On April 10, 2025, the US FDA announced that it has a long-term plan to eliminate conventional animal testing in drug development, starting with monoclonal antibodies (mAbs).[ 1] Instead, within 3-5 years, the expectation will be to leverage an integrated safety assessment approach, combining information from a comprehensive battery of New Approach Methodologies (NAM).
Science Daily: Pharmacology News
APRIL 16, 2025
According to new research next-generation DNA sequencing (NGS) -- the same technology which is powering the development of tailor-made medicines, cancer diagnostics, infectious disease tracking, and gene research -- could become a prime target for hackers.
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Covalent Modifiers
APRIL 13, 2025
Tyler M. McCullough, Vishakha Choudhary, David L. Akey, Meredith A. Skiba, Steffen M. Bernard, Jeffrey D. Kittendorf, Jennifer J. Schmidt, David H. Sherman, and Janet L. Smith ACS Catalysis 2024 14 (16), 12551-12563 DOI: 10.1021/acscatal.4c03637 Emerging antibiotic resistance requires continual improvement in the arsenal of antimicrobial drugs, especially the critical macrolide antibiotics.
BioPharma Drive: Drug Pricing
APRIL 16, 2025
Two studies published in Nature found stem cell-derived products can not only be safely transplanted into the brain, but also show promising — albeit unproven — signs of efficacy.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drugs.com
APRIL 15, 2025
TUESDAY, April 15, 2025 — A newly approved antibiotic to treat urinary tract infections may also help fight drug-resistant gonorrhea, a new study shows. The medication, called gepotidacin, sold under the brand name Blujepa, could become the.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Covalent Modifiers
APRIL 12, 2025
Pasquale A. Morese, Ayaz Ahmad, Mathew P. Martin, Richard A. Noble, Sara Pintar, Lan Z. Wang, Shangze Xu, Andrew Lister, Richard A. Ward, Agnieszka K. Bronowska, Martin E. M. Noble, Hannah L. Stewart & Michael J. Waring Commun Chem 8 , 111 (2025). [link] The discovery of targeted covalent inhibitors is of increasing importance in drug discovery.
BioPharma Drive: Drug Pricing
APRIL 14, 2025
The Commerce Department has begun a so-called Section 232 investigation into the national security effects of the U.S. importing pharmaceuticals and their starting materials.
Drugs.com
APRIL 14, 2025
MONDAY, April 14, 2025 -- Worried about taking the ADHD meds youve been prescribed because they might harm your heart health?Theres no need to fret, according to a new evidence review.ADHD medications generally have just a small effect on a per.
Science Daily: Pharmacology News
APRIL 17, 2025
How do we learn new things? Neurobiologists using cutting-edge visualization techniques have revealed how changes across our synapses and neurons unfold. The findings depict how information is processed in our brain's circuitry, offering insights for neurological disorders and brain-like AI systems.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Covalent Modifiers
APRIL 13, 2025
Waldmann H, Zhang R, liu J, Gasper R, Janning P. ChemRxiv. 2025 doi:10.26434/chemrxiv-2025-70x40. [link] For targeted covalent protein modification at low reactivity aspartates and glutamates, new methods are in high demand. Inspired by the HaloTag technology we have developed a new technique which employs a reaction between chloroalkane-functionalised ligands and a specific glutamate residue.
BioPharma Drive: Drug Pricing
APRIL 18, 2025
The leaked budget draft, if approved by Congress, would reduce the FDA’s budget authority, indicating more disruption could be in store for an agency already shaken by large-scale layoffs.
Drugs.com
APRIL 17, 2025
THURSDAY, April 17, 2025 -- Common medications like aspirin, ibuprofen, statins and beta blockers appear to slow the progress of Parkinsons disease, a new study says.Parkinsons symptoms took nearly a decade longer to crop up in patients taking the.
Science Daily: Pharmacology News
APRIL 16, 2025
Astronomers have detected the most promising signs yet of a possible biosignature outside the solar system, although they remain cautious.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Collaborative Drug
APRIL 18, 2025
CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:
BioPharma Drive: Drug Pricing
APRIL 16, 2025
The biotech is developing an experimental drug for the most common of a family of disorders all caused by errors in glycosylation.
Drugs.com
APRIL 14, 2025
MONDAY, April 14, 2025 -- When officials in Wisconsin's largest city asked the U.S. Centers for Disease Control and Prevention (CDC) for help dealing with high levels of lead in city schools, the answer wasn't what they expected. The CDC said no.
Science Daily: Pharmacology News
APRIL 16, 2025
A new study suggests the universe may rotate -- just extremely slowly. The finding could help solve one of astronomy's biggest puzzles.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
LifeSciVC
APRIL 17, 2025
By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Drug discovery and development is a long, and often fraught, journey it typically takes more than a decade to progress from idea to approved drug, and less than 10% of drugs that enter the clinic succeed in achieving commercialization. Creating new drugs for patients is certainly not for the faint of heart.
BioPharma Drive: Drug Pricing
APRIL 16, 2025
The advisory committee, which met Tuesday for the first time since Robert F. Kennedy Jr. was sworn in as health secretary, also discussed the Texas measles outbreak.
Drugs.com
APRIL 16, 2025
WEDNESDAY, April 16, 2025 -- Middle-aged folks and seniors whose weed use lands them in the hospital are at higher risk for developing dementia within a matter of years, a new study says.An ER visit or hospitalization due to cannabis use is.
Science Daily: Pharmacology News
APRIL 16, 2025
Affectionate mothering in childhood may have a lasting impact on important personality traits, potentially influencing life outcomes such as educational achievement, economic success, and health and well-being, according to new research. The findings suggest that positive maternal parenting could foster important traits such as openness, conscientiousness and agreeableness.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Collaborative Drug
APRIL 13, 2025
Lets talk security - Why a bug bounty may be more valuable than a penetration test
BioPharma Drive: Drug Pricing
APRIL 16, 2025
The company’s board reiterated its recommendation to instead pursue an offer from SK Capital and Carlyle that’s worth about $29 million upfront.
Drugs.com
APRIL 14, 2025
MONDAY, April 14, 2025 -- The U.S. Food and Drug Administration announced it is shifting away from animal testing in the development of monoclonal antibody therapies and other drugs, favoring more effective, human-relevant methods.The new strategy.
Science Daily: Pharmacology News
APRIL 14, 2025
CT scans may account for 5% of all cancers annually, according to a new study that cautions against overusing and overdosing CTs. The danger is greatest for infants, followed by children and adolescents. But adults also are at risk, since they are the most likely to get scans.
Codon
APRIL 17, 2025
In the early 2010s, Chilean plant ecologists Ernesto Gianoli and Fernando Currasco-Urra spotted what looked like a peculiar tree stem in the rainforest. On closer inspection, they realized it was a vine, Boquila trifoliolata , imitating a nearby tree’s leaves — closely matching their size, shape, and vein patterns. After further study, Gianoli and Carrasco-Urra discovered that this aptly named “Chameleon Vine” could mimic all sorts of plants, or even multiple different pl
BioPharma Drive: Drug Pricing
APRIL 14, 2025
As first quarter earnings begin, executives are confronting market turmoil, regulatory instability and the threat of U.S. tariffs on their products.
Drugs.com
APRIL 18, 2025
FRIDAY, April 18, 2025 — A new pill designed to help with weight loss and blood sugar control is showing promise in early studies. Eli Lilly said its experimental drug, orforglipron, helped people with type 2 diabetes lower their blood sugar.
Science Daily: Pharmacology News
APRIL 16, 2025
Astronomers have found a planet that orbits at an angle of 90 degrees around a rare pair of peculiar stars. This is the first time we have strong evidence for one of these 'polar planets' orbiting a stellar pair.
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