Drug Discovery World

MAY 15, 2024

Dr Catherine Beech , CEO at Exonate and Dr Pete Adamson , CSO at Breye Therapeutics discuss the need for better therapies to treat diabetic retinal disease and current progress in the field. Diabetic retinal disease, termed diabetic retinopathy (DR), is a significant risk factor for people with Type I or II diabetes, and one that increases with time as patients experience repeated and continued issues with glycaemic control.

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Science Daily: Pharmacology News

MAY 15, 2024

It's one thing to dream up a quantum internet that could send hacker-proof information around the world via photons superimposed in different quantum states. It's quite another to physically show it's possible. That's exactly what physicists have done, using existing Boston-area telecommunication fiber, in a demonstration of the world's longest fiber distance between two quantum memory nodes to date.

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BioPharma Drive: Drug Pricing

MAY 16, 2024

The biotech, tentatively named Hercules CM Newco, has rights to three incretin drugs discovered by Jiangsu Hengrui Pharmaceuticals, two of which are in clinical testing.

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Drugs.com

MAY 16, 2024

THURSDAY, May 16, 2024 -- Following a vegetarian or vegan diet might just buy you a longer, healthier life, a new review finds.Staying away from meat was tied to a reduced risk of heart disease, cancer and early death, researchers reported in a.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

MAY 17, 2024

Deepika Khedekar , Associate Centralized Clinical Trial Lead at IQVIA Inc, looks at the challenges of utilising artificial intelligence (AI) in oncology clinical research. Ten million 1 people around the world die from cancer each year. Yet, while the number of cancer clinical trials has soared from 19,211 in 2013 to a whopping 26,396 in 2022 3 , and they keep surging in 2024, the success stories are few and far between.

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Trials Clinical Trials Treatment Research 147

Science Daily: Pharmacology News

MAY 15, 2024

A team of researchers has developed a drone that flies autonomously using neuromorphic image processing and control based on the workings of animal brains. Animal brains use less data and energy compared to current deep neural networks running on GPUs (graphic chips). Neuromorphic processors are therefore very suitable for small drones because they don't need heavy and large hardware and batteries.

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Research 131

Chemical Biology and Drug Design

MAY 17, 2024

The study screened and identified furochromenones that impact tyrosinase activity. One of the furochromenones ( 3k ) inhibited while another ( 4f ) stimulated tyrosinase. Abstract Tyrosinase is a copper-containing enzyme involved in the biosynthesis of melanin pigment. While the excess production of melanin causes hyperpigmentation of human skin, hypopigmentation results in medical conditions like vitiligo.

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Drug Discovery World

MAY 16, 2024

Work has started on a £60 ($75.1) million development in Manchester intended to enhance the city’s Oxford Road Corridor knowledge quarter as a hub for life sciences and technology innovation. Greenheys at Manchester Science Park is scheduled for completion in Summer 2026 and will span 131,000 sq ft across six floors. The development will include specialised laboratory spaces tailored for diagnostics, genomics, biotech and precision medicine businesses.

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Science Daily: Pharmacology News

MAY 15, 2024

Research could pave the way for a prosthetic hand and robot to be able to feel touch like a human hand. The technology could also be used to help restore lost functionality to patients after a stroke.

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Research 131

BioPharma Drive: Drug Pricing

MAY 16, 2024

While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.

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Drugs Research 124

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Clinical Trials

Drugs.com

MAY 15, 2024

WEDNESDAY, May 15, 2024 -- An experimental gene therapy could one day provide a first-ever cure for genital and oral herpes, researchers report.The gene therapy removed 90% or more of oral herpes infection in lab mice, and it also suppressed how.

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Therapies Research 119

Drug Discovery World

MAY 15, 2024

The Novo Nordisk Foundation, Wellcome, and the Bill & Melinda Gates Foundation have announced a new partnership to support critical scientific research and development (R&D) for global health. The partnership is focused on supporting science and innovation to advance solutions that are accessible and affordable to people in low- and middle-income countries (LMICs).

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Science Daily: Pharmacology News

MAY 15, 2024

Instead of burning fossil fuels to smelt steel and cook cement, researchers in Switzerland want to use heat from the sun. The proof-of-concept study uses synthetic quartz to trap solar energy at temperatures over 1,000 C (1,832 F), demonstrating the method's potential role in providing clean energy for carbon-intensive industries.

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Research 127

BioPharma Drive: Drug Pricing

MAY 16, 2024

The results, which showed Lilly’s drug was as effective at controlling blood sugar as standard injections, come as Novo Nordisk seeks approval for a competing once-weekly insulin.

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Drugs 117

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

MAY 15, 2024

WEDNESDAY, May 15, 2024 -- The U.S. Food and Drug Administration has approved a kit that will allow women to collect their own vaginal sample for HPV screening, a move that could increase early detection in those at risk for cervical cancer. Women.

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FDA Approval FDA Drugs 116

Drug Discovery World

MAY 14, 2024

Semaglutide (the active ingredient in Wegovy and Ozempic) can produce clinically meaningful weight loss and delivers significant cardiovascular benefits, according to two studies presented at the European Congress on Obesity (ECO). The studies are based on the Semaglutide and Cardiovascular Outcomes (SELECT) trial, the largest and longest clinical trial of the effects of semaglutide on weight in over 17,000 adults.

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Disease Clinical Trials Drugs Trials 147

Science Daily: Pharmacology News

MAY 17, 2024

The latest findings forecast that global life expectancy will increase by 4.9 years in males and 4.2 years in females between 2022 and 2050. Increases are expected to be largest in countries where life expectancy is lower, contributing to a convergence of increased life expectancy across geographies. The trend is largely driven by public health measures that have prevented and improved survival rates from cardiovascular diseases, COVID-19, and a range of communicable, maternal, neonatal, and nut

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Disease 124

BioPharma Drive: Drug Pricing

MAY 15, 2024

The annual forecast, which comes as Eisai and Biogen have begun submitting a more convenient form of Leqembi for approval, looks “more realistic” than previous guidance, according to Jefferies analysts.

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Drugs 117

Drugs.com

MAY 15, 2024

WEDNESDAY, May 15, 2024 -- The H5N1 avian flu virus has been discovered in a small number of wild birds in New York City.The highly infectious and severe virus was detected in fecal samples in six New York City birds representing four different.

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Virus 115

Drug Discovery World

MAY 14, 2024

DDW’s Megan Thomas talks to Dr Henrik Jespersen, Head of Melanoma Oncology, at Oslo University Hospital. MT: Where do you work, and can you tell us what you’re working on at the moment? HJ: I work as a clinical oncologist at Oslo University Hospital where I am head of melanoma oncology. I have a particular interest in tumour immunology and the melanoma subtype that arises in parts of the eye called uveal melanoma.

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Science Daily: Pharmacology News

MAY 16, 2024

Researchers used generative AI to develop a physics-informed technique to classify phase transitions in materials or physical systems that is much more efficient than existing machine-learning approaches.

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Research 122

FDA Law Blog: Biosimilars

MAY 13, 2024

By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — FDA has long touted the use of real-world evidence ( RWE ). Extolling RWE, FDA has said “RWE can be leveraged to bring new products to market, evaluate the safety and effectiveness of existing products for new uses, and assess the continued performance and safety of products once on the market.

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Drugs.com

MAY 17, 2024

FRIDAY, MAY 17, 2024 -- The U.S. Food and Drug Administration on Thursday approved a new drug to treat patients with an advanced form of deadly lung cancer. Importantly, tarlatamab (Imdelltra) is only for patients who have exhausted all other.

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FDA Approval FDA Drugs 112

Drug Discovery World

MAY 14, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Tien Lee, CEO of Aardvark Therapeutics, a San Diego-based biotech company in Phase II studies of its drug, ARD-101, a type 2 bitter taste receptor (TAS2R) which is taken orally and remains in the human gut unlike GLP-1 which is systemic.

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Regulations Science Drugs 147

Science Daily: Pharmacology News

MAY 17, 2024

An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.

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Perficient: Drug Development

MAY 14, 2024

In the ever-evolving landscape of healthcare, trust reigns supreme. As consumers increasingly rely on data to inform their decisions, the healthcare industry faces a pressing need to not only meet but exceed expectations. With disruptive forces emerging from various corners, healthcare organizations find themselves in a race to create personalized experiences that foster lasting engagement and trust.

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Drugs.com

MAY 17, 2024

FRIDAY, May 17, 2024 -- Mice, rats and other wildlife can pick up bacteria called leptospira from water or soil and excrete it in urine. If your dog contacts any soil or water contaminated by the germ (especially if they have an open wound) they.

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Drug Discovery World

MAY 13, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. A leading news story this week has been the announcement of positive Phase II results of a head and neck cancer trial, but there have been a number of other interesting clinical result announcements.

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Science Daily: Pharmacology News

MAY 13, 2024

Today's rate of atmospheric carbon dioxide increase is 10 times faster than at any other point in the past 50,000 years, researchers have found through a detailed chemical analysis of ancient Antarctic ice.

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BioPharma Drive: Drug Pricing

MAY 16, 2024

Full study results disclosed ahead of a medical meeting showed elinzanetant consistently reduced the frequency and severity of hot flashes.

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Trials Drugs 117

Drugs.com

MAY 17, 2024

FRIDAY, May 17, 2024 -- Cutting-edge cancer treatments are essentially useless for patients barely clinging to life, a new study shows.Chemotherapies, immunotherapies, targeted therapies and hormone therapies do not improve survival rates in.

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Drug Discovery World

MAY 13, 2024

Reece Armstrong speaks to Melanie Adams-Cioaba , Senior Director and General Manager of pharma (cryo-EM), Thermo Fisher Scientific about advances in vaccine design. RA: How can rational design approaches help advance vaccine development? MA: Regarding vaccine development specifically, and the role my team plays in the development of cryogenic electron microscopy (cryo-EM) technology, we see the study and dissemination of virus structures, and the proteins that comprise them, as vital to vacc

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Science Daily: Pharmacology News

MAY 14, 2024

Cinematography techniques can significantly increase user engagement with virtual environments and, in particular, the aesthetic appeal of what users see in virtual reality.

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MAY 14, 2024

We’re excited to announce our Data Cloud Expert specialization! This is the highest level of Salesforce-validated expertise for Data Cloud. This achievement isn’t just a milestone, it’s a testament to our commitment to revolutionizing how businesses leverage their data to drive business outcomes, unlock trapped data, and enhance customer experiences.

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