Engineering Protein Production Virus 
Broad Institute
JANUARY 14, 2025
His lab had just developed base editing, a gene-editing approach that makes single-letter changes in DNA and can shut down protein production using strategies including installing a stop signal in the genetic code. They then administered the AAVs to mice infected with the human prion protein.
Codon
JULY 28, 2025
For the former, clinicians extract a patient’s cells, engineer them in a laboratory, and then infuse them back into the body. Some diseases are caused by mutations in large genes that exceed the packaging limits of existing vectors like adeno-associated virus (AAV). Vectors also differ in the duration of their expression.
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The Pharma Data
JULY 3, 2025
“We are evolving from licensing our technology in support of therapeutic and vaccine development into a revenue-focused bioprocessing protein platform business,” said Joe Hazelton, President and Chief Operating Officer of Dyadic. Our C1 and Dapibus™ production platforms remain the engines we expect to drive commercial execution.
Drug Target Review
APRIL 5, 2024
Together, these attributes provide a strong foundation for protein expression with enough adaptability to produce much of the commercial and therapeutic protein market. Skilled CDMOs can also locate or create favourable genomic microenvironments where transcription factors are efficiently recruited, further boosting protein production.
The Pharma Data
MARCH 23, 2022
To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives.
The Pharma Data
DECEMBER 22, 2020
SAITAMA, Japan–( BUSINESS WIRE )– After a capital increase in the initial closing of its series A round, with investments by Mitsubishi UFJ Capital and Real Tech Fund , Epsilon Molecular Engineering Inc. The bio industry has progressed to a point where it deals with proteins from an engineering perspective.
Codon
MARCH 20, 2023
🧪 Papers AI + Bio Protein-specific signal peptides for mammalian vector engineering. Evolutionary-scale prediction of atomic-level protein structure with a language model. Biological Engineering Generation of functional oocytes from male mice in vitro. Metabolic Engineering. Metabolic Engineering.
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