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Automated red blood cell exchange: bridging treatment gaps in sickle cell disease care

Drug Target Review

Currently, three FDA-approved disease-modifying drug therapies are available: hydroxyurea, crizanlizumab and L-glutamine, though each has limitations that affect patient compliance. The use of FDA-approved medications for preventing vaso-occlusive events in sickle cell disease. JAMA Netw Open. 2023 Nov 1;6(11):e2344546.

Disease 52
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Leveraging ADCs in precision oncology strategy

Drug Target Review

At a base-layer, Caris’ comprehensive molecular profiling that we perform for patients today can identify predictive biomarkers for current FDA-approved ADCs. His work has been published in many high-impact journals and presented at international oncology meetings. Examples include HER2-low and FOLR1.

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A Visual Guide to Genome Editors

Codon

The treatment, now known as Casgevy, became the first CRISPR-based therapy to gain FDA approval, in 2023. Gray, in London to discuss the significance of her recovery at the Third International Summit on Human Genome Editing , described Casgevy as “a new beginning for people with sickle cell disease.”

DNA 78
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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

The project is a collaboration between the Broad and the African Center of Excellence for Genomics of Infectious Diseases (ACEGID) at Redeemer’s University outside Lagos in Nigeria, where Happi is a professor of molecular biology and genomics. Sooner than planned, Sentinel would be put to the test.

Virus 132
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Forty of the Nation’s Most Talented Young Scientists Named Finalists in Regeneron Science Talent Search 2021

The Pharma Data

Through its world-class competitions, including the Regeneron Science Talent Search, the Regeneron International Science and Engineering Fair, the Broadcom MASTERS, and its award-winning magazine, Science News and Science News for Students, Society for Science is committed to inform, educate, and inspire.

Science 40
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The Promise of Gas Vesicles

Codon

Klebahn placed the algae cells into an enclosed chamber beneath his light microscope, and then pumped in air until its internal pressure rose to twice, then three-times, normal atmospheric levels. By measuring the length of time that it takes for a soundwave to enter and return, an ultrasound device constructs an internal image of the body.

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AI at the forefront of age-related disease treatment

Drug Target Review

There are currently no FDA-approved treatments for the condition and the potential to improve outcomes for older patients suffering from this debilitating condition is immense. Ann has successfully attracted international investors, securing funds from seed stage to series B.

Disease 59