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What single cells are revealing about brain disorders

Drug Target Review

From maths and physics to molecular biology Schnall-Levin did not begin in the life sciences. “I I started looking around and getting interested in biology. I got my eyes opened to molecular biology, bioinformatics, computational biology and these emerging fields at the time.”

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Altasciences at ASGCT 2025: An Open Forum for All Things Gene and Cell Therapy | By Kaylyn Koenig

Alta Sciences

From groundbreaking science to next-gen technologies, the energy at this year’s conference was undeniable. I also walked attendees through some of our DNA and RNA isolation techniques and our molecular biology laboratory’s experience in collecting samples and isolating genetic material to assess germline integration after preclinical studies.

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A Visual Guide to Genome Editors

Codon

The core of the CRISPR immune response is a guide RNA (gRNA) that binds to a CRISPR-associated (Cas) protein. This article provides a summary of the major CRISPR systems, 2 including the naturally occurring CRISPR-Cas9, -Cas12, and -Cas13 systems, as well as base editors, prime editors, and the recently uncovered bridge RNA system.

DNA 83
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Levers for Biological Progress

Codon

I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecular biology. Scientists are already building a model that can, for example, look at which RNA molecules are expressed in a cell at t=0 and predict how those molecules will change at t=1.

DNA 133
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Scientists discover network of cells and genes involved in Crohn’s disease complication

Broad Institute

Isselbacher Professor of Medicine at Harvard Medical School, and director of the Center for Computational and Integrative Biology and core member in the Department of Molecular Biology at Massachusetts General Hospital. Lingjia Kong, a research scientist in the Xavier lab, is the first author on the study. and Harry B.

Disease 111
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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

This method was more about serendipity than science. But as molecular biology has advanced, so too has our approach to finding new drugs. Another promising avenue is the use of technologies like RNA interference and gene editing, which allow scientists to turn off the production of certain proteins altogether.

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F. William Studier receives the 2024 Merkin Prize in ceremony at the Broad Institute for developing technology used to produce millions of doses of COVID-19 vaccines

Broad Institute

William Studier receives the 2024 Merkin Prize in ceremony at the Broad Institute for developing technology used to produce millions of doses of COVID-19 vaccines The groundbreaking, scalable technology is widely used in laboratories around the world today to efficiently produce large amounts of protein and RNA. Merkin (left) and F.

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