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Issue 07 is Coming on Monday

Codon

How Science Becomes Mature. Slime Mold Time Mold argues that maturity — in biology, chemistry, or anything else — requires mechanical models and the ability to talk about nuts, bolts, and the parameters that constrain how they behave. A History of Fermentation.

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Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical for Your Gene Therapy Studies

Alta Sciences

PJ: At Altasciences, we have a range of leading-edge platforms that include ligand binding assays (LBA), NAb, TAb, flow cytometry, and ELISpot, as well as on-site molecular biology instrumentation such as Bio-Rad’s ddPCR system, the NanoDropTM One spectrophotometer, and dedicated polymerase chain reaction (PCR) chambers.

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Sosei Heptares’ COVID-19 Program Identifies Potent Broad Spectrum Anti-Viral Small Molecules for Further Development

The Pharma Data

The program is being led by Sosei Heptares and progressed in collaboration with multiple companies including Syngene International, Domainex, Fidelta, o2h Discovery, Piramal, WuXi AppTec and the MRC Laboratory of Molecular Biology. Zhang, et al, Science (2020) DOI: 10.1126/science.abb3405. References. Hilgenfeld, Febs J.

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A Visual Guide to Genome Editors

Codon

If the same virus invades the cell a second time, the gRNA’s spacer sequence will bind to the matching viral DNA sequence, then be cut by the Cas protein. in Molecular Biology from Princeton University and also writes about science fact and fiction on Substack. He earned his A.B.

DNA 79
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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

Technological advances in genomics and data sciences have the potential to transform how we think about detecting and treating deadly and pervasive diseases like Ebola,” Sabeti said. Since 2007, they’d been studying Lassa fever, an often deadly illness caused by infection with the Lassa virus, which is endemic in West Africa.

Virus 132
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Scaling Phage Therapy

Codon

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 137
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Repurposing FDA-approved drugs may help combat COVID-19

The Pharma Data

. “The SARS-CoV-2 vaccines target the spike protein, but this protein is under strong selection pressure and, as we have seen with Omicron, can undergo significant mutations,” said Joyce Jose, assistant professor of biochemistry and molecular biology, Penn State. 25) in the journal Communications Biology. .