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A spatial approach to understanding drug dynamics using mass spectrometry imaging

Drug Target Review

2025 Feb 4 About the authors Steve Castellino – Chief Analytics Officer & Principal Investigator, GlycoPath Steve Castellino received his BA in Chemistry from California State University, Long Beach, and his PhD in Organic Chemistry from the University of California, Riverside. Toxicologic Pathology.

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Nixing the Newborn Screening Advisory Committee Is Ill-Advised

PLOS: DNA Science

Baby’s First Test categorizes the entries: amino acid, endocrine, fatty acid oxidation, and hemoglobin disorders; lysosomal storage diseases; organic acid conditions; and others. It is jargony enough to reawaken nightmares of taking organic chemistry. The value of newborn screening transcends the youngest among us.

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New chemical process makes it easier to craft amino acids that don't exist in nature

Science Daily: Pharmacology News

Chemists describe a powerful new way to create new-to-nature, 'unnatural' amino acids, which could find use in protein-based therapies and open up novel branches of organic chemistry.

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API Processes in the Pharmaceutical Industry

DS in Pharmatics

I earned a Bachelor of Science in Chemistry at Fairfield University in 1979 and a Ph.D. in Organic Chemistry at Yale University in 1984 […] James Mencel’s Guidanceabout Scaling Up API Processes. Could you please introduce yourself and your expertise in the pharmaceutical industry?

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Women in Stem with Dr Emily Leproust

Drug Target Review

I started my journey in chemistry – first as an undergraduate and then in my PhD programme at the University of Houston, where I focused on organic chemistry and nucleic acids chemistry. They had the science and the technology but not the business model. Twist was officially founded in 2013.

DNA
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Bavtavirine

New Drug Approvals

Benzonitrile, 4-[[4-amino-8-[4-[(1 E )-2-cyanoethenyl]-2,6-dimethylphenyl]-2-quinazolinyl]amino]- Gilead Sciences, Inc.; Institute of Organic Chemistry and Biochemistry of the AS CR, v.v.i. Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitors (NNRTIs).

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Welcome to new Director David Hulcoop

The Open Targets Blog

After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. I knew I wanted to stay close to science, but I wanted a new adventure. The Open Targets role was in a different area of science, at the other end of the drug discovery process.