CDD Presenting at COMP Together, November 14 – UCSF Campus
Collaborative Drug
NOVEMBER 1, 2023
CDD Presenting at COMP Together, November 14 -UCSF campus
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Recorded Presentations: CDD 20th Anniversary User Group Meeting
Collaborative Drug
APRIL 22, 2024
Recorded Presentations from CDD Experts
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CDD Exhibiting and Presenting at ACS Fall 2023, August 13th to 17th
Collaborative Drug
AUGUST 1, 2023
CDD Exhibiting and Presenting at ACS Fall 2023, August 13th to 17th.
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Scientists Developing Vaccine Against Present and Future COVID Viruses
Drugs.com
MAY 6, 2024
MONDAY, May 6, 2024 -- Scientists are busy working on a vaccine that might fight strains of the COVID virus SARS-CoV-2 that haven't even emerged yet.The effort from a British team at the University of Cambridge is already showing promise in mouse.
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AstraZeneca drug could help keep a common breast cancer at bay
BioPharma Drive: Drug Pricing
JUNE 1, 2025
Data presented at ASCO show that swapping in the oral drug camizestrant for an older therapy helped sustain the benefit of initial treatment, potentially opening a novel step in patient care.
Drugs 270
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Astronomers observe largest ever sample of galaxies up to over 12 billion light years away
Science Daily: Pharmacology News
MAY 19, 2025
The largest sample of galaxy groups ever detected has been presented by a team of international astronomers using data from the James Webb Space telescope (JWST) in an area of the sky called COSMOS Web.
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CDD Exhibiting and Presenting at Discovery on Target 2023, Boston, September 25-28
Collaborative Drug
SEPTEMBER 21, 2023
Join CDD at Discovery on Target 2023, Sept 25-28. Explore CDD vault at Booth 209 and accelerate your product development.
Production 290
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Models show intensifying wildfires in a warming world due to changes in vegetation and humidity; only a minor role for lightning
Science Daily: Pharmacology News
FEBRUARY 12, 2025
Climate scientists present a realistic supercomputer simulation that resolves the complex interactions between fire, vegetation, smoke and the atmosphere. The authors find that increasing greenhouse gas emissions will likely increase the global lightning frequency by about 1.6%
171 
Milk on ice: Antarctic time capsule of whole milk powder sheds light on the enduring qualities--and evolution--of dairy products past and present
Science Daily: Pharmacology News
MARCH 27, 2024
In a remarkable discovery, whole milk powder manufactured in New Zealand in 1907 and transported to Antarctica with explorers seeking the South Pole was unveiled after more than a century. The find has allowed dairy researchers to answer the question: Is the milk we enjoy today different from the milk consumed in previous generations?
Production 293
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New data showcase promise, growing pains of CAR-T in autoimmune disease
BioPharma Drive: Drug Pricing
JUNE 17, 2024
One expert described trial results presented at EULAR last week as “unprecedented.” ” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.
Disease 349
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The risk of global water scarcity is greater when accounting for the origin of rain
Science Daily: Pharmacology News
SEPTEMBER 2, 2024
Researchers are now presenting an alternative method for quantifying the global risk of water scarcity. Securing the world's water supply is one of the greatest challenges of our time.
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Organic material from Mars reveals the likely origin of life's building blocks
Science Daily: Pharmacology News
JULY 1, 2024
The study presents solid evidence for a prediction made over a decade ago that could be key to understanding how organic molecules, the foundation of life, were first formed here on Earth. Two samples from Mars together deliver clear evidence of the origin of Martian organic material.
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Forever Chemicals found in bottled and tap water from around the world
Science Daily: Pharmacology News
OCTOBER 17, 2024
Scientists have discovered toxic 'Forever Chemicals' present in samples of drinking water from around the world.
312 
First conclusive evidence that a terrestrial leech species can jump
Science Daily: Pharmacology News
JUNE 20, 2024
A new study presents video evidence that at least one species of terrestrial leech can jump, behavior that scientists have debated for more than a century.
318 
Site-Specific Molecular Glues for the 14-3-3/Tau pS214 ProteinProtein Interaction via Reversible Covalent Imine Tethering
Covalent Modifiers
FEBRUARY 10, 2025
This work presents the identification and early-stage optimization of small molecule fragment-like stabilizers for a specific binding site of the 14-3-3/Tau PPI.
An ant that selectively amputates the infected limbs of wounded sisters
Science Daily: Pharmacology News
JULY 2, 2024
When experimentally testing the effectiveness of these 'treatments,' not only did they aid in recovery, but the research team found the ants' choice of care catered to the type of injury presented to them.
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Roche weighs whether speedy approval path is open for latest Alzheimer’s drug
BioPharma Drive: Drug Pricing
OCTOBER 31, 2024
In an investor presentation, executives hinted at the possibility of seeking an accelerated approval of trontinemab if it can significantly lower levels of amyloid in a Phase 3 trial.
Trials 307
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Dinosaurs roamed the northern hemisphere millions of years earlier than previously thought, according to new analysis of the oldest North American fossils
Science Daily: Pharmacology News
JANUARY 7, 2025
A newly described dinosaur whose fossils were recently uncovered is challenging the existing narrative, with evidence that the reptiles were present in the northern hemisphere millions of years earlier than previously known.
307 
New evidence pushes back arrival of early hominins in Europe
Science Daily: Pharmacology News
JANUARY 24, 2025
Research reveals new evidence of early hominin activity in Europe, suggesting that hominins were present on the continent far earlier than previously thought.
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Genetic tracing at the Huanan Seafood market further supports COVID animal origins
Science Daily: Pharmacology News
SEPTEMBER 19, 2024
A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).
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Return of the elephants seals: From a few to thousands
Science Daily: Pharmacology News
SEPTEMBER 27, 2024
The research shows that this species narrowly escaped extinction by hunting, resulting in lasting genetic effects in the present population. A new international study has revealed the genetic impact of hunting in northern elephant seals.
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Global retreat of glaciers has strongly accelerated
Science Daily: Pharmacology News
FEBRUARY 19, 2025
Researchers present a global assessment of ice loss since the beginning of the millennium. In a global comparison, the glaciers in the Alps and Pyrenees are melting the fastest.
Research 296
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Structural Basis for Substrate Binding, Catalysis and Inhibition of Breast Cancer Target Mitochondrial Creatine Kinase by Covalent Inhibitor via Cryo-EM
Covalent Modifiers
FEBRUARY 6, 2025
Herein, we present mutational and structural investigations on understudied ubiquitous MtCK that showed closure of the loop comprising His61 is specific to and relies on creatine binding and mechanism of phosphoryl transfer depends on electrostatics of active site.
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Quantum research breakthrough uses synthetic dimensions to efficiently process quantum information
Science Daily: Pharmacology News
OCTOBER 17, 2024
The work presents a method for manipulating the photonic states of light in a never-before-seen way, offering greater control over the evolution of photon propagation. This control makes it possible to improve the detection and number of photon coincidences, as well as the efficiency of the system.
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Ancient DNA reveals Indigenous dog lineages found at Jamestown, Virginia
Science Daily: Pharmacology News
AUGUST 16, 2024
Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs.
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Kinetic Modeling of Covalent Inhibition: Effects of Rapidly Fluctuating Intermediate States
Covalent Modifiers
JUNE 2, 2025
In the present analysis, we expand the intermediate state into two conformationsreactive (EI) and nonreactive (EI).
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Rewriting the evolutionary history of critical components of the nervous system
Science Daily: Pharmacology News
AUGUST 13, 2024
The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
302 
Weight-Loss Pill Saxenda Helps Kids as Young as 6
Drugs.com
SEPTEMBER 11, 2024
11, 2024 -- The weight-loss drug liraglutide helped obese children lower their BMI and reach a healthier weight, researchers report.The findings, published Tuesday in the New England Journal of Medicine and presented. WEDNESDAY, Sept.
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Alcohol raises heart disease risk, particularly among women
Science Daily: Pharmacology News
MARCH 28, 2024
Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a study presented at the American College of Cardiology's Annual Scientific Session.
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Methods for Kinetic Evaluation of Reversible Covalent Inhibitors from Time-Dependent IC50 Data
Covalent Modifiers
MARCH 24, 2025
Herein, we present an implicit equation that can estimate these constants from incubation time-dependent IC50 values and a numerical modelling method, EPIC-CoRe, that can fit these kinetic parameters from pre-incubation time-dependent IC50 data.
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Neuroscientists spark shelter-seeking response by reactivating memory circuit
Science Daily: Pharmacology News
OCTOBER 1, 2024
Using a sophisticated brain-imaging system, neuroscientists say they have successfully reactivated a specific memory circuit in mice, causing them to seek out shelter when no shelter is actually present.
286 
CG follows big IPO with new results for bladder cancer drug
BioPharma Drive: Drug Pricing
MAY 3, 2024
Newly disclosed Phase 3 results presented Friday match findings the biotech disclosed last year, while offering a more comprehensive look at how its drug stacks up to rival therapies.
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Researchers devise new way to target and correct disease-related proteins
Broad Institute
JANUARY 6, 2025
These compounds bring together two proteins in the cell that might not normally find each other a target protein (often the one altered in disease), and a presenter protein that has some effect on the target. For their presenter protein, they chose FKBP12, a well-studied protein that is abundant in human cells.
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Space oddity: Most distant rotating disc galaxy found
Science Daily: Pharmacology News
OCTOBER 7, 2024
Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. Researchers have discovered the most distant Milky-Way-like galaxy yet observed.
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New Hope Against a Rare, Aggressive Form of Thyroid Cancer
Drugs.com
OCTOBER 28, 2024
But some patients can present with what's known as an anaplastic thyroid carcinoma (ATC) -- a rare and very aggressive tumor with a very poor prognosis. MONDAY, Oct. 28, 2024 -- Most thyroid cancers are slow-moving and, if caught early, curable.
283 
Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking
Science Daily: Pharmacology News
DECEMBER 14, 2023
However, this protective effect is lost when only single species of gut bacteria are present. New study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms.
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Oldest-known evolutionary 'arms race'
Science Daily: Pharmacology News
JANUARY 3, 2025
A new study presents what is believed to be the oldest known example in the fossil record of an evolutionary arms race.
287 
Some mice may owe their monogamy to a newly evolved type of cell
Science Daily: Pharmacology News
MAY 15, 2024
Scientists discover the cells and hormones that inspire mice to nurture their young; the same hormones are also present in humans. The answer may be a previously unknown hormone-generating cell.
311 
Nanosized blocks spontaneously assemble in water to create tiny floating checkerboards
Science Daily: Pharmacology News
JUNE 13, 2024
The work presents a simple approach to create complex nanostructures through a technique called self-assembly. Researchers have engineered nanosized cubes that spontaneously form a two-dimensional checkerboard pattern when dropped on the surface of water.
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Two of the Milky Way's earliest building blocks identified
Science Daily: Pharmacology News
MARCH 21, 2024
The new find is the astronomical equivalent of archeologists identifying traces of an initial settlement that grew into a large present-day city.
324 
Weather-changing El Nino oscillation is at least 250 million years old
Science Daily: Pharmacology News
OCTOBER 21, 2024
A new modeling study shows that the El Nino event, a huge blob of warm ocean water in the tropical Pacific Ocean that can change rainfall patterns around the globe, was present at least 250 million years in the past, and was often of greater magnitude than the oscillations we see today.
283 
More plants on the menu of ancient hunter-gatherers
Science Daily: Pharmacology News
APRIL 29, 2024
A new study challenges this notion by presenting compelling isotopic evidence of a strong preference for plants among 15,000-year-old hunter-gatherers from Morocco. However, due to the scarcity of well-preserved human remains from Paleolithic sites, little information exists about the dietary habits of pre-agricultural human groups.
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Latest AI Has 100% Success Rate in Spotting Melanomas
Drugs.com
OCTOBER 13, 2023
New research presented Wednesday at a medical conference in Berlin shows that this AI technology now has a 100% detection. FRIDAY, Oct. 13, 2023 -- The ability to detect skin cancer using artificial intelligence (AI) software has rapidly improved.
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Biodegradable 'living plastic' houses bacterial spores that help it break down
Science Daily: Pharmacology News
APRIL 30, 2024
Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle. A new type of bioplastic could help reduce the plastic industry's environmental footprint.
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