Drugs.com
JUNE 2, 2025
MONDAY, June 2, 2025 Removing fluoride from the U.S. water supply could result in more than 25 million more decayed teeth in children and teenagers within five years, a new study warns.Thats the equivalent of a decayed tooth for 1 of every 3 kid.
BioPharma Drive: Drug Pricing
JUNE 2, 2025
The oncology giant will pay $1.5 billion to co-develop a BioNTech drug that targets the proteins PD1 and VEGF, following Merck, and Pfizer into what’s become a competitive development race.
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Science Daily: Pharmacology News
JUNE 2, 2025
A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain -- offering hope for a new generation of drug-free treatments.
Covalent Modifiers
JUNE 2, 2025
Kyle Ghaby, Benot Roux bioRxiv 2025.05.28.656658; doi: [link] There is increasing interest in the discovery of small-molecule inhibitors that form covalent bonds with their targets for therapeutic applications. Nevertheless, identifying clear rational design principles remains challenging because the action of these molecules cannot be understood as common noncovalent inhibitors.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Collaborative Drug
JUNE 4, 2025
A practical guide to selecting the right ELN or LIMS for early-stage drug discovery, focusing on usability, structure search, and scalability.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
JUNE 3, 2025
TUESDAY, June 3, 2025 -- The U.S. Food and Drug Administration has approved a new lower-dose vaccine for active immunization against COVID-19 caused by severe acute respiratory syndrome coronavirus 2. The new vaccine (mNexspike [COVID-19 Vaccine.
BioPharma Drive: Drug Pricing
JUNE 2, 2025
Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.
Perficient: Drug Development
JUNE 2, 2025
In this era of Web development, Next.JS and Vercel is the powerful couple. Next.JS offers performance, scalability and flexibility in building web applications whereas Vercel provides the easy and smooth deployment experience tailored for it. Today, in this blog, we will cover the step-by-step process of deploying a Next.JS app on Vercel. We will also cover some best practices and key configurations to ensure the optimal performance in production.
Drug Target Review
JUNE 2, 2025
Bioconjugates are rapidly emerging as a key frontier in targeted therapies, particularly through Antibody-Drug Conjugates (ADCs) , which combine antibodies with cytotoxic drugs to deliver more precise and effective treatments. This fusion enables precise delivery of potent drugs directly to cancer cells or other targeted tissues, significantly improving the therapeutic impact while minimising harm to healthy cells.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Broad Institute
JUNE 4, 2025
Bindcraft Workshop By Rose Circeo June 4, 2025 Breadcrumb Home Bindcraft Workshop November 6, 2025 12:00-4:00 pm Workshop (lunch served) 4:00-5:00 pm Broad Institute museum tour Registration opens June 9. Presenter Lennart Nickel, Doctoral Assistant in the Laboratory of Protein Design & Immunoengineering at EPFL. Proteinprotein interactions are central to biological function, making their design highly relevant for therapeutic and biotechnological applications.
Drug Patent Watch
JUNE 2, 2025
"The Patent Paradox: How Big Pharma's Web of Exclusivity is Suffocating Innovation As the world grapples with the rising costs of healthcare, a hidden culprit is quietly strangling the development of life-saving treatments: the 'patent thicket.' In a system designed to incentivize innovation, these complex webs of exclusive rights are instead fueling a culture of exploitation, where pharmaceutical giants use their patents to stifle competition and reap exorbitant profits.
Drugs.com
JUNE 4, 2025
WEDNESDAY, June 4, 2025 Pepto Bismol is a go-to stomach remedy, but a new study suggests it might not help prevent diarrhea during international travel.The study, led by the U.S. Centers for Disease Control and Prevention (CDC), found that people.
BioPharma Drive: Drug Pricing
JUNE 4, 2025
The company is one of the first to receive a “platform technology designation,” which could speed the review of certain gene therapy applications it later brings to the regulator.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
JUNE 2, 2025
Mobile App development is rapidly growing and so is the expectation of robust support. “Mobile first” is the set paradigm for many application development teams. Unlike web deployment, an app release has to go through the review process via App Store Connect and Google Play. Minor or major releases follow the app review same process, which can take 1-4 days.
Crown Bioscience
JUNE 4, 2025
Revamping Test Methods: A Leap Towards Non-Animal Approaches The age-old practice of animal experiments is on the cusp of transformation. The shift is driven by a myriad of changes. Our expert guest, Professor Thomas Hartel , Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health provides his industry insights into new approaches drug discovery through technologies such as organoids and Artificial Intelligence (AI).
Quanticate
JUNE 4, 2025
Explore how automation AI and digital tools are redefining clinical trials. Discover innovations driving faster, smarter and more ethical research.
Chemical Biology and Drug Design
JUNE 4, 2025
Combining previous research, compound SJL2-1 was identified through virtual screening based on molecular docking. By reducing the expression levels of PRMT5 and AR, it exhibits anti-proliferative effects, inhibits cell migration and invasion abilities, blocks the cell cycle, and induces apoptosis in AR-sensitive prostate cancer and CRPC. ABSTRACT Protein arginine methyltransferase 5 (PRMT5) is an epigenetic-related enzyme that has been shown to be a promising target for the treatment of human ca
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JUNE 4, 2025
WEDNESDAY, June 4, 2025 Troubled children and teenagers are languishing hours in chaotic hospital emergency rooms, waiting for a psychiatric bed to open, a new study says.About 1 in 3 kids who go to an emergency room (ER) amid a mental health c.
BioPharma Drive: Drug Pricing
JUNE 4, 2025
Enhertu, Datroway and other antibody-drug conjugates developed by Daiichi Sankyo have made the company a leader in a competitive field. Hiroyuki Okuzawa is working to keep it that way.
Perficient: Drug Development
JUNE 4, 2025
We are thrilled to announce that Juan Cardona Ramirez has been recognized as a Databricks Partner Champion , making him the first Perficient colleague in Latin America to earn this prestigious designation. This recognition celebrates Juans deep technical expertise , consistent contributions, and commitment to innovation within the Databricks ecosystem.
Fierce BioTech
JUNE 4, 2025
Where Your Next Biotech Breakthrough Could Begin In Puerto Rico, companies tap into decades of experience in scientific innovation, business-friendly incentives and public-private partnerships to push new frontiers of medicine. Join a dynamic ecosystem on the cutting-edge of biotech production and R&D. scox Wed, 06/04/2025 - 09:43 In Puerto Rico, companies tap into decades of experience in scientific innovation, business-friendly incentives and public-private partnerships to push new frontie
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Broad Institute
JUNE 4, 2025
Talk title coming soon By Nadya Karpova June 4, 2025 Talk title coming soon Lorin Crawford Microsoft Research New England (MSR) Add to calendar Talks Search - Any - Fall 2025 Spring 2025 Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014
Chemical Biology and Drug Design
JUNE 4, 2025
The novel repurposed antibacterial drug besifloxacin led to an 83% reduction of murine kidney fungal burden as compared to no-drug control. It showed positive synergism with a lower than MIC dose of fluconazole (0.5mg/L) proposing its use in combination therapy against Candida infections. ABSTRACT Emergence of life-threatening fungal infections like systemic candidiasis concurrently with bacterial infections and limitations of current antifungal therapies warrant the discovery of novel inhibitor
Drugs.com
JUNE 4, 2025
WEDNESDAY, June 4, 2025 A morning cup of coffee might do more than momentarily boost your energy and spirits.Full-test java also appears to help women age more gracefully, a new study says.Middle-aged women who regularly drank caffeinated coffee w.
BioPharma Drive: Drug Pricing
JUNE 2, 2025
The pharma giant is betting that Blueprint, whose research revolves around a certain kind of tyrosine kinase, will be a boost to its immunology business.
LifeSciVC
JUNE 5, 2025
By Arthur Tzianabos, CEO of Lifordi Immunotherapeutics, as part of the From The Trenches feature of LifeSciVC Its easy to jump on the negative bandwagon these days when news in our world and industry is focused on doom & gloom. In biotech, headlines and daily conversations lean heavily toward company layoffs, shutdowns, pipeline pare-backs, regulatory setbacks, depressed valuations, and what feels like impossible situations.
thought leadership
JUNE 5, 2025
So, you're thinking about Technology Transfers (i.e., TT, Tech Transfer)? Who can blame you? There has been a significant amount of news recently regarding tariffs and the potential for bringing manufacturing back to the United States. If your manufacturing is outside the United States, then this news will certainly keep Tech Transfer on your mind. Of course, technology transfers occur for other reasons.
Drug Target Review
JUNE 5, 2025
Despite recent advances in gene therapy for sickle cell disease (SCD) , automated red blood cell exchange (aRBCX) remains a cornerstone therapy that plays a vital yet underutilised role in managing complications and enhancing quality of life for millions living with this devastating condition worldwide. Dr Aaron Haubner, Senior Manager of North America Medical Affairs and Market Access at Terumo Blood and Cell Technologies , reveals that while promising new treatments emerge, urgent partnerships
Chemical Biology and Drug Design
JUNE 2, 2025
This study investigates the neuroprotective effects of Kisspeptin-54 in ischemic stroke. In mice with induced stroke, Kisspeptin-54 reduced brain damage, improved neurological function, and restored occludin levels, strengthening the bloodbrain barrier. The findings reveal that Kisspeptin-54 enhances endothelial resilience through GATA-4-driven occludin expression, suggesting a promising therapeutic approach for stroke treatment.
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