Trending Articles

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Fluoride Ban Could Create Cavities For 1 Of Every 3 U.S. Kids

Drugs.com

MONDAY, June 2, 2025 Removing fluoride from the U.S. water supply could result in more than 25 million more decayed teeth in children and teenagers within five years, a new study warns.Thats the equivalent of a decayed tooth for 1 of every 3 kid.

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Bristol Myers allies with BioNTech on bispecific cancer drug

BioPharma Drive: Drug Pricing

The oncology giant will pay $1.5 billion to co-develop a BioNTech drug that targets the proteins PD1 and VEGF, following Merck, and Pfizer into what’s become a competitive development race.

Drugs 293
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Leprosy existed in America long before arrival of Europeans

Science Daily: Pharmacology News

Long considered a disease brought to the Americas by European colonizers, leprosy may actually have a much older history on the American continent. Scientists reveal that a recently identified second species of bacteria responsible for leprosy, Mycobacterium lepromatosis, has been infecting humans in the Americas for at least 1,000 years, several centuries before the Europeans arrived.

Disease 310
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Kinetic Modeling of Covalent Inhibition: Effects of Rapidly Fluctuating Intermediate States

Covalent Modifiers

Kyle Ghaby, Benot Roux bioRxiv 2025.05.28.656658; doi: [link] There is increasing interest in the discovery of small-molecule inhibitors that form covalent bonds with their targets for therapeutic applications. Nevertheless, identifying clear rational design principles remains challenging because the action of these molecules cannot be understood as common noncovalent inhibitors.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Precision medicine’s next frontier: unlocking the power of biospecimens

Fierce BioTech

In conversation with Fierce Biotechs Chris Hayden, Austin Read, head of PPD CorEvitas Precision Medicine, Thermo Fisher Scientific, unpacks the evolving landscape of precision therapeutic and di | Austin Read of Thermo Fisher Scientific discusses how combining biospecimens with real-world data is advancing diagnostics, treatment and the future of patient care.

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Feeling Work Stress? Your Dog Might Be Feeling It Too

Drugs.com

SATURDAY, May 31, 2025 Stress from work doesnt always stay at the office and it may be affecting more than just your mood. A new study finds that your dog may be picking up on it, too, especially if you have a hard time letting go of work worri.

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At ASCO, Enhertu cements growing role in stomach cancer care

BioPharma Drive: Drug Pricing

AstraZeneca and Daiichi Sankyo’s drug extended survival by 30% compared to a widely used regimen, further establishing its importance as a second-line treatment option.

Treatment 196
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How to Choose the Right ELN or LIMS for Early-Stage Drug Discovery

Collaborative Drug

A practical guide to selecting the right ELN or LIMS for early-stage drug discovery, focusing on usability, structure search, and scalability.

Drugs 130
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Deploying a Scalable Next.js App on Vercel – A Step-by-Step Guide

Perficient: Drug Development

In this era of Web development, Next.JS and Vercel is the powerful couple. Next.JS offers performance, scalability and flexibility in building web applications whereas Vercel provides the easy and smooth deployment experience tailored for it. Today, in this blog, we will cover the step-by-step process of deploying a Next.JS app on Vercel. We will also cover some best practices and key configurations to ensure the optimal performance in production.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Birds nested in Arctic alongside dinosaurs

Science Daily: Pharmacology News

Spring in the Arctic brings forth a plethora of peeps and downy hatchlings as millions of birds gather to raise their young. The same was true 73 million years ago, according to a new article. The paper documents the earliest-known example of birds nesting in the polar regions.

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Pepto Bismol May Not Prevent Traveler’s Diarrhea, New Study Finds

Drugs.com

WEDNESDAY, June 4, 2025 Pepto Bismol is a go-to stomach remedy, but a new study suggests it might not help prevent diarrhea during international travel.The study, led by the U.S. Centers for Disease Control and Prevention (CDC), found that people.

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Vera drug scores in closely watched study in rare kidney disease

BioPharma Drive: Drug Pricing

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.

Disease 184
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Strategic planning in ADC development: insights from Lonza

Drug Target Review

Bioconjugates are rapidly emerging as a key frontier in targeted therapies, particularly through Antibody-Drug Conjugates (ADCs) , which combine antibodies with cytotoxic drugs to deliver more precise and effective treatments. This fusion enables precise delivery of potent drugs directly to cancer cells or other targeted tissues, significantly improving the therapeutic impact while minimising harm to healthy cells.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Over The Air Updates for React Native Apps

Perficient: Drug Development

Mobile App development is rapidly growing and so is the expectation of robust support. “Mobile first” is the set paradigm for many application development teams. Unlike web deployment, an app release has to go through the review process via App Store Connect and Google Play. Minor or major releases follow the app review same process, which can take 1-4 days.

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Save twice the ice by limiting global warming

Science Daily: Pharmacology News

A new study finds that if global warming exceeds the Paris Climate Agreement targets, the non-polar glacier mass will diminish significantly. However, if warming is limited to 1.5 degrees Celsius, at least 54 per cent could be preserved -- more than twice as much ice as in a 2.7 C scenario.

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Preemptive Kidney Transplants Add No Benefit, Study Says

Drugs.com

WEDNESDAY, June 4, 2025 Folks who might need a kidney transplant in the future shouldnt rush to get one, a new study says.Patients gain no benefit from getting a donated kidney before their own kidneys deteriorate to the point that they require d.

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Sanofi to acquire Blueprint for up to $9.5B

BioPharma Drive: Drug Pricing

The pharma giant is betting that Blueprint, whose research revolves around a certain kind of tyrosine kinase, will be a boost to its immunology business.

Research 157
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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The Dark Reality of Drug Patent Thickets: Innovation or Exploitation?

Drug Patent Watch

"The Patent Paradox: How Big Pharma's Web of Exclusivity is Suffocating Innovation As the world grapples with the rising costs of healthcare, a hidden culprit is quietly strangling the development of life-saving treatments: the 'patent thicket.' In a system designed to incentivize innovation, these complex webs of exclusive rights are instead fueling a culture of exploitation, where pharmaceutical giants use their patents to stifle competition and reap exorbitant profits.

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Bindcraft Workshop

Broad Institute

Bindcraft Workshop By Rose Circeo June 4, 2025 Breadcrumb Home Bindcraft Workshop November 6, 2025 12:00-4:00 pm Workshop (lunch served) 4:00-5:00 pm Broad Institute museum tour Registration opens June 9. Presenter Lennart Nickel, Doctoral Assistant in the Laboratory of Protein Design & Immunoengineering at EPFL. Proteinprotein interactions are central to biological function, making their design highly relevant for therapeutic and biotechnological applications.

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Does planting trees really help cool the planet?

Science Daily: Pharmacology News

Replanting forests can help cool the planet even more than some scientists once believed, especially in the tropics. But even if every tree lost since the mid-19th century is replanted, the total effect won't cancel out human-generated warming.

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Dads Help Shape Eating Habits of Their Children

Drugs.com

MONDAY, June 2, 2025 A dads eating habits can have a profound effect on their kids diets, even when those children are nothing but a twinkle in his eye, a new study says.Men who established a healthy diet as teens were more likely to model healt.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Full Arvinas, Pfizer data confirm potential and limits of ‘Protac’ drug in breast cancer

BioPharma Drive: Drug Pricing

While vepdegestrant outperformed a standard treatment option in a subtype of patients, the benefit on progression-free survival was modest.

Treatment 167
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Oracle Fusion new Product Management Landing Page and AI (25B)

Perficient: Drug Development

We have been hearing about AI in many different ways and technology pioneers have been slowly introducing AI in our daily lives. When it comes to Fusion Applications, Oracle has invested in built-in AI capabilities across all platforms and Supply Chain area is not an exception. In this blog, I would like to discuss the newly designed Product Management Redwood Experience and a few AI capabilities that comes out of of the box.

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Good Review Management Principles & Practices, Part One: Fundamental Values

thought leadership

On Tuesday, September 25 th , the FDA published a draft guidance containing recommendations on good review management principles and practices (GRMPs) for new drug applications (NDAs), Biologics license applications (BLAs), or efficacy supplements/supplements with clinical data. The document, entitled Good Review Management Principles and Practices for New Drug Applications and Biologics License Applications , applies to human drug applications and biosimilar biological product applications.

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Brain training game offers new hope for drug-free pain management

Science Daily: Pharmacology News

A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain -- offering hope for a new generation of drug-free treatments.

Drugs 184
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Troubled Kids Wait a Half-Day — Or More — In ER To Get Mental Health Care

Drugs.com

WEDNESDAY, June 4, 2025 Troubled children and teenagers are languishing hours in chaotic hospital emergency rooms, waiting for a psychiatric bed to open, a new study says.About 1 in 3 kids who go to an emergency room (ER) amid a mental health c.

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Genetics is a missing link in kidney disease drug development

BioPharma Drive: Drug Pricing

Genetic research is driving progress in kidney disease drug discovery.

Disease 147
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Beyond Animal Testing: The Rise of Organoids and AI Tools

Crown Bioscience

Revamping Test Methods: A Leap Towards Non-Animal Approaches The age-old practice of animal experiments is on the cusp of transformation. The shift is driven by a myriad of changes. Our expert guest, Professor Thomas Hartel , Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health provides his industry insights into new approaches drug discovery through technologies such as organoids and Artificial Intelligence (AI).

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Automation in Clinical Trials: AI, eConsent, and Digital Tools Driving Innovation

Quanticate

Explore how automation AI and digital tools are redefining clinical trials. Discover innovations driving faster, smarter and more ethical research.