Science Daily: Pharmacology News
MAY 29, 2025
Long considered a disease brought to the Americas by European colonizers, leprosy may actually have a much older history on the American continent. Scientists reveal that a recently identified second species of bacteria responsible for leprosy, Mycobacterium lepromatosis, has been infecting humans in the Americas for at least 1,000 years, several centuries before the Europeans arrived.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The agency recommends manufacturers update their vaccines to target the JN.1 strain. At the same time, HHS head Robert F. Kennedy Jr. is removing guidance that healthy children and pregnant women receive COVID shots.
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Covalent Modifiers
MAY 25, 2025
Dandan Zhu, Zijian Zheng, Huixin Huang, Xiaojuan Chen, Shuhong Zhang, Zhuchu Chen, Ting Liu, Guangyu Xu, Ying Fu, Yongheng Chen, European Journal of Medicinal Chemistry , 2025 [link] Fibroblast growth factor receptors (FGFRs) represent promising therapeutic targets in various malignancies, yet the clinical application of FGFR covalent inhibitors has been impeded by several significant challenges, including unquantifiable target engagement, undefined off-target effects, and the emergence of drug
Drugs.com
MAY 27, 2025
TUESDAY, May 27, 2025 -- The U.S. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3 percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drug Patent Watch
MAY 27, 2025
"Unlock Hidden Profits in Pharmaceutical R&D: A recent analysis of top-selling medications reveals that companies that closely monitor their competitors' patent portfolios are 3x more likely to achieve a higher return on investment in drug development. By staying one step ahead of the competition, can you revolutionize your approach to pharmaceutical innovation?
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Covalent Modifiers
MAY 27, 2025
Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C. Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyov, Dirk Scharn, Mark A. Pearson, Johannes Popow, Anna C. Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L. Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John V.
BioPharma Drive: Drug Pricing
MAY 27, 2025
City will receive $46 million from Biogen under the alliance. Elsewhere, Angelini Pharma licensed a rare disease therapy and the FDA refused to review a Savara lung drug.
Drug Target Review
MAY 26, 2025
The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We considered the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work
New Drug Approvals
MAY 26, 2025
Ervogastat CAS 2186700-33-2 Non-alcoholic Steatohepatitis (NASH) with Liver Fibrosis (FAST TRACK – U.S.) 2-[5-[(3-Ethoxy-2-pyridinyl)oxy]-3-pyridinyl]- N -[(3 S )-tetrahydro-3-furanyl]-5-pyrimidinecarboxamide ( S )-2-(5-((3-Ethoxypyridin-2-yl]oxy]pyridin-3-yl)- N -(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide PF 06865571 BSOIY5AKQW 407.4 g/mol, C 21 H 21 N 5 O 4 2-[5-(3-ethoxypyridin-2-yl)oxypyridin-3-yl]- N -[(3 S )-oxolan-3-yl]pyrimidine-5-carboxamide Originator Pfizer Class Amides; Eth
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MAY 29, 2025
Replanting forests can help cool the planet even more than some scientists once believed, especially in the tropics. But even if every tree lost since the mid-19th century is replanted, the total effect won't cancel out human-generated warming.
Covalent Modifiers
MAY 28, 2025
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, Stephen Wilkinson, Stephanie Harlfinger, Graham Smith, Jason G Kettle, Michael Niedbala, Stefan Kavanagh, Dominic P Williams Toxicology Research , 2025, 14, 3, tfaf054, [link] Interest in inhibiting target proteins through covalent binding mechanisms has increased in the last decade due to the potential for beneficial pharmacological properties.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The startup is the latest beneficiary of investors’ appetite for protein-degrading technology, which offers a way to reach drug targets other technologies can’t.
Perficient: Drug Development
MAY 27, 2025
In the ever-evolving world of content management systems (CMS), there are many options to choose fromWordPress, Joomla, Drupal, and others. But for developers who love clean code, flexibility, and control, October CMS stands out as a modern, elegant solution built on the popular Laravel PHP framework. What is October CMS? October CMS is an open-source, free CMS that makes web building easier without compromising power or flexibility.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
thought leadership
MAY 29, 2025
On Tuesday, September 25 th , the FDA published a draft guidance containing recommendations on good review management principles and practices (GRMPs) for new drug applications (NDAs), Biologics license applications (BLAs), or efficacy supplements/supplements with clinical data. The document, entitled Good Review Management Principles and Practices for New Drug Applications and Biologics License Applications , applies to human drug applications and biosimilar biological product applications.
Science Daily: Pharmacology News
MAY 29, 2025
Anthropologists have examined the societal consequences of global glacier loss.
Fierce BioTech
MAY 27, 2025
Is it time to go beyond classic design in oncology trials? jgrcic Tue, 05/27/2025 - 11:55 Tue, 05/27/2025 - 11:55 Resource Type Whitepaper Promotion Start Tue, 05/27/2025 - 12:06 Use of healthy volunteers in first-in-human trials with oncology small molecules. Can an alternative approach expedite clinical development of small molecule oncology drugs and benefit patients?
BioPharma Drive: Drug Pricing
MAY 27, 2025
The demand for fill/finish services has never been greater, how are CDMOs responding?
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Perficient: Drug Development
MAY 27, 2025
In todays world, the Internet of Things (IoT) is revolutionizing industries across the globe by connecting devices, systems, and people in ways that were once unimaginable. From smart homes to advanced manufacturing, IoT is creating new opportunities for innovation, efficiency, and data-driven decision-making. At the forefront of this transformation is Microsoft Azure, a cloud computing platform that has become a powerhouse for IoT operations.
thought leadership
MAY 29, 2025
On Wednesday, August 1 st , FDA released a notice with updated prescription drug user fee rates for fiscal year 2019.
Science Daily: Pharmacology News
MAY 29, 2025
A new study finds that if global warming exceeds the Paris Climate Agreement targets, the non-polar glacier mass will diminish significantly. However, if warming is limited to 1.5 degrees Celsius, at least 54 per cent could be preserved -- more than twice as much ice as in a 2.7 C scenario.
Fierce BioTech
MAY 29, 2025
Novel Cell Lysis Solution: Simplifying Scalable Viral Vector Harvest Download our free whitepaper to discover how you can boost lysis efficiency, maximize viral yield, and streamline your downstream process. smarcus Thu, 05/29/2025 - 10:25 Download our free whitepaper to discover how you can boost lysis efficiency, maximize viral yield, and streamline your downstream process.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
MAY 27, 2025
Integrated informatics platforms boost R&D speed, data qualityand ROI across BioPharma
Alta Sciences
MAY 29, 2025
A Novel Approach for Improved Bioavailability in Solid Dosage Forms tchichekian Fri, 05/30/2025 - 02:59 Publication Spray-Drying-Nanosuspensions-ebook.
Perficient: Drug Development
MAY 31, 2025
We have been hearing about AI in many different ways and technology pioneers have been slowly introducing AI in our daily lives. When it comes to Fusion Applications, Oracle has invested in built-in AI capabilities across all platforms and Supply Chain area is not an exception. In this blog, I would like to discuss the newly designed Product Management Redwood Experience and a few AI capabilities that comes out of of the box.
Science Daily: Pharmacology News
MAY 26, 2025
Contrary to widespread assumptions, the largest shark that ever lived -- Otodus megalodon -- fed on marine creatures at various levels of the food pyramid and not just the top. Scientists analyzed the zinc content of a large sample of fossilized megalodon teeth, which had been unearthed above all in Sigmaringen and Passau, and compared them with fossil teeth found elsewhere and the teeth of animals that inhabit our planet today.
Broad Institute
MAY 27, 2025
Gene editing disrupts Huntingtons mutation in mice By Allessandra DiCorato May 27, 2025 Breadcrumb Home Gene editing disrupts Huntingtons mutation in mice Making single-letter edits in stretches of repeated DNA stopped or reversed the genetic change that causes Huntingtons disease and Friedreichs ataxia. By Allessandra DiCorato May 27, 2025 Credit: Agnieszka Grosso, Broad Communications Related news More versatile and efficient base editor unlocks new gene-editing targets Researchers extend powe
BioPharma Drive: Drug Pricing
MAY 31, 2025
AstraZeneca and Daiichi Sankyo’s drug extended survival by 30% compared to a widely used regimen, further establishing its importance as a second-line treatment option.
Alta Sciences
MAY 27, 2025
Highlights From the 17th Minipig Research Forum, by Shant Jackson pmjackson Tue, 05/27/2025 - 18:06 I recently had the chance to attend the 17th Minipig Research Forum (MRF) in Amsterdamand what an experience! This was my first time attending the forum, and visiting the Netherlands! It was a fantastic opportunity to connect with fellow experts in the nonclinical research space about topics specific to miniature swine.
Drug Target Review
MAY 26, 2025
Daniel Galbraith, Chief Scientific Officer at Solvias , brings extensive expertise in the pharmaceutical and biotechnology sectors. In his role, he provides both strategic and technical guidance to Solvias, a global Contract Research Organisation (CRO) that offers critical analytical services to the pharmaceutical industry. With a particular focus on biologics, cell, and gene therapies, Galbraiths work is centred on equipping drug developers with the tools, insights, and support needed to advanc
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