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Time for change: non-human primates in drug research

Drug Target Review

Persistent challenges with NHP use Despite their biological relevance, using live NHPs in research poses several major challenges: Ethical concerns NHPs, due to their advanced cognition and social behaviour, are at the centre of ongoing ethical debates. Supply chain disruptions Availability is a critical bottleneck in NHP-based research.

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A Visual Guide to Genome Editors

Codon

Researchers have since discovered variants of the protein with additional useful qualities. Researchers have also discovered a slew of small Cas9s — some less than half the size of the S. By cutting DNA with CRISPR, researchers can therefore scramble the genetic code in a way that disables the targeted gene.

DNA 81
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How organoids can redefine pre-clinical research

Drug Target Review

Organoid technologies are becoming an invaluable solution for preclinical research, with the ability to augment the development of personalised medicine, drug discovery and gene therapies. The derived drug was given to both patients, to which researchers report the patients saw significant improvement. Nat Rev Neurol [Internet].

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Jennifer Listgarten

Broad Institute

Jennifer Listgarten By Rose Circeo April 22, 2024 Jennifer Listgarten Jennifer Listgarten is a Professor in the Department of Electrical Engineering and Computer Science, the Center for Computational Biology, and the Bioengineering program at the University of California, Berkeley. She completed her Ph.D.

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Women in Stem with Lidia Pieri

Drug Target Review

After ten years of exciting postdoctoral research around Europe in the astroparticle physics sector, hunting for dark matter at yet another offer from a foreign institution, I chose to create space for my life instead. Pure theoretical research is not in my chords, and I felt uncomfortable not being challenged by data. To participate.

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Gamma delta T cells: a rising star in cancer therapy

Drug Target Review

Preclinical research on γδ T cells has made great strides since the cells were first identified in the 1980s, with γδ T-cell therapies from several companies, including IN8bio, now in or nearing clinical trials for various cancers. Mr Ho has worked in the biotechnology industry for almost 20 years.

Therapies 105
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The evolution of cell therapy to address unmet medical needs

Drug Target Review

Because this programme is still in early research, we are not at a point we can say we definitely know what it is going to work best in setting X or setting Y. Prior to joining Lineage, Mr Culley served from August 2017 to September 2018 as interim Chief Executive Officer at Artemis Therapeutics, Inc. SVRA) in April 2017.