Broad Institute

DECEMBER 13, 2023

2023 Cohort By Rose Circeo December 13, 2023 Breadcrumb Home Broad Biomedical Post-baccalaureate Scholars Program 2023 Cohort John Adeleye Townson University Healthcare Administration, B.S. Hung Group, Infectious Disease and Microbiome Program Michael Bogaev Princeton University Molecular Biology (major), B.A.,

Molecular Biology 52

Molecular Biology Cell Biology Science Engineering 52

SCIENMAG: Medicine & Health

SEPTEMBER 7, 2023

New York, NY (September 7, 2023)—Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs.

Molecular Biology 96

Molecular Biology Drugs Research 96

Drug Target Review

FEBRUARY 19, 2024

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Beate joined Cytiva in early 2023, having held senior leadership positions at Sanofi and Bayer.

Molecular Biology 110

Molecular Biology Science Protein Expression Production 110

Elrig

APRIL 6, 2023

Research & Innovation 2023 Roundup Blog Research & Innovation 2023 Roundup Blog It was great to welcome so many people to the Research and Innovation 2023: Accelerating Future Drug Discovery event last week in Hinxton, Cambridge, UK.

Research 40

Research Molecular Biology Science Drugs 40

Fierce BioTech

JUNE 6, 2023

jsabatino Tue, 06/06/2023 - 09:31 Harwell Campus offers rich opportunities for pioneering NAT technology on all fronts, and the campus is attracting biotechnology companies of all sizes – from Moderna to start-ups to Government research institutes and accelerators. Download here!

Science 52

Science Therapies Molecular Biology Government 52

Drug Target Review

SEPTEMBER 22, 2023

The substantial value of organoids is becoming increasingly recognised by supportive government initiatives developing novel drugs, with a growth rate of 22 percent between 2023 and 2030 and a market size predicted to reach over US $6.5 2023 May;30(5):571–91. 2023 Mar 18;2200333:2200333. 2023 Jan 19;1(1):32–45.

Clinical Research 116

Clinical Research Research Drug Development Science 116

Broad Institute

AUGUST 16, 2023

Nuclear DNA influences variation in mitochondrial DNA By Allessandra DiCorato August 16, 2023 Breadcrumb Home Nuclear DNA influences variation in mitochondrial DNA Whole genomes from hundreds of thousands of people reveal new complexity in how the nuclear and mitochondrial genomes interact, which may influence how cells produce energy.

DNA 98

DNA Molecular Biology Disease Regulations 98

Broad Institute

JULY 13, 2023

A how-to for performing quantitative bioimaging By Makenzie Kohler July 13, 2023 Breadcrumb Home A how-to for performing quantitative bioimaging Bioimaging expert Beth Cimini discusses a comprehensive online guide aimed at making quantitative imaging more accessible. PLOS Biology. Online June 27, 2023, DOI: 10.1371/journal.pbio.3002167

Molecular Biology 98

Molecular Biology Laboratories Research 98

Drug Target Review

DECEMBER 7, 2023

Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. 2011 January 1 [2023 November 21]; 1(1):31-45. Phages in nature. Bacteriophage.

RNA 59

RNA Immune Response DNA Molecular Biology 59

Drug Target Review

OCTOBER 3, 2024

Methods in Molecular Biology. Journal of Molecular Biology. Crescioli S, Kaplon H, Chenoweth A, et al. Antibodies to watch in 2024. 2024 Jan 5;16(1). FDA no longer needs to require animal tests before human drug trials [Internet]. www.science.org. Available from: [link] ‌Baker M. 2015 May;521(7552):274–6. 2021;291–306.

Molecular Biology 52

Molecular Biology Pharmacokinetics Laboratories Animal Testing 52

Alta Sciences

JUNE 11, 2024

Our experts have over five years of experience with CRISPR gene-editing therapeutics in nonhuman primates (NHPs) and extensive expertise in bioanalysis for biodistribution studies, in addition to many molecular biology platforms , such as ligand binding assays (LBA), NAbs, TAbs, flow cytometry , and ELISpot.

Therapies 52

Therapies Molecular Biology Immune Response Science 52

Drug Target Review

FEBRUARY 28, 2024

Dr Rochlin earned a PhD in Molecular Biology and Genetics from Weill Cornell Medical College, conducting research at Sloan Kettering Institute, and a BA in Biology from the University of Pennsylvania. Sci Rep 11:21133 (2023). and MBA students with real-world consulting experiences. Fisher J, Anderson.

Therapies 105

Therapies Engineering Molecular Biology Science 105

Elrig

APRIL 29, 2024

Fascinated by the potential of AI in medical research, I transitioned to BenevolentAI in early 2023 as a Biology Project Leader. Having a combination of computational skills & scientific knowledge such as molecular biology, genomics is also important.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

Broad Institute

NOVEMBER 17, 2023

Evan Macosko (HMS) novel cell populations molecular biology, microfluidics, and organic chemistry Neurobiology His research develops new genomic technologies to identify how each cell type contributes to brain function and where each gene acts.

Organic Chemistry 52

Organic Chemistry Engineering Molecular Biology Disease 52

Drug Target Review

OCTOBER 25, 2024

2023, September 9). 2023, July 24). Progress in molecular biology and translational science. References Juganavar, A., Joshi, A., & Shegekar, T. Navigating early alzheimer’s diagnosis: A comprehensive review of diagnostic innovations. link] Devi, G. link] Pugazhenthi, S. 2017, February 4). link] Smets, Bart, et al.

Disease 59

Disease Clinical Trials Therapies Science 59

Broad Institute

AUGUST 7, 2023

A surprising new role for a major immune regulator By Tom Ulrich August 7, 2023 Breadcrumb Home A surprising new role for a major immune regulator By Anne Trafton, MIT News August 7, 2023 Credit: RCSB Protein Data Bank A model of the human STING protein. Online August 3, 2023. Paper Cited Liu B, Carlson R, et al.

Regulations 91

Regulations Clinical Trials Engineering Science 91

Drug Target Review

MARCH 15, 2024

Not for use in diagnostic procedures About the author © 2023 KP Visions #Revvity Dr Anis H Khimani Senior Strategy Leader, Life Sciences strategy group, Revvity, Inc. He has a post-doctorate in virology, viral pathogenesis, viral vector development, and vaccines evaluation from Harvard Medical School, and a PhD in virology/molecular biology.

Engineering 105

Engineering Molecular Biology Protein Expression Medical Schools 105

Broad Institute

JUNE 21, 2023

said Vamsi Mootha , senior author of the study, an institute member at the Broad, professor of systems biology and medicine at Harvard Medical School, and professor of molecular biology at Massachusetts General Hospital. Human Molecular Genetics. Online June 1, 2023. PLOS Biology. Online May 23, 2023.

Treatment 98

Treatment Disease Molecular Biology Medical Schools 98

Vial

MARCH 1, 2024

By geographical region, the global CRO services market in 2023 was dominated by North America. billion in 2023 attributable to its laboratory products and biopharma services segment (53.8% Largest CROs by Revenue In a 2023 report by Statista, the largest CROs worldwide were Thermo Fisher Scientific Inc., of total revenue).

Clinical Trials 52

Clinical Trials Clinical Research Trials Laboratories 52

Codon

FEBRUARY 13, 2024

Fast forward to 2023. ” A Global View Even as advances in computing and molecular biology usher in the era of a new, high-tech “phage therapy 2.0”, At least a million people die from drug-resistant bacterial infections every year. Nearly three million drug-resistant infections occur annually in the U.S.

Therapies 138

Therapies Virus DNA Clinical Trials 138

Agency IQ

JANUARY 19, 2024

Stakeholders were invited to submit comments on the revised guideline to EMA and FDA until early 2023. Finally, in November 2023, the ICH Assembly reviewed the EWG’s amended version of the guideline and signed off on its adoption and implementation. The Specific Precautions section (6.2.7) also received some additions.

Virus 40

Virus Science Production FDA 40

Codon

JULY 11, 2023

It is the untouchable foundation of molecular biology. The ribosome is a molecular printer that threads ‘beads’ onto a protein string. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein. But we will try to convince you that, perhaps, we can do better.

RNA 75

RNA DNA Engineering Laboratories 75

Codon

MARCH 12, 2023

I recently asked for recommendations of “classic” papers in molecular biology. 1/2 5:04 AM ∙ Feb 25, 2023 2,559 Likes 348 Retweets This tool also looks interesting, but you definitely should not use it. 2:19 PM ∙ Mar 6, 2023 2 Likes 1 Retweet 17 of 31. Hoist the colors!

DNA 52

DNA Engineering Therapies RNA 52

Codon

JULY 11, 2023

It is the untouchable foundation of molecular biology. The ribosome is a molecular printer that threads ‘beads’ onto a protein string. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein. But we will try to convince you that, perhaps, we can do better.

RNA 52

RNA DNA Engineering Laboratories 52

Broad Institute

JANUARY 30, 2024

He majored in biological chemistry at the University of Chicago and during his junior year, he had a fortuitous meeting with his academic advisor about finding a student research position that would let him dive more deeply into the molecular details of biological systems. A combined MD/PhD program offered both opportunities.

Hospitals 137

Hospitals Virus Medical Schools Science 137

Drug Target Review

FEBRUARY 15, 2024

Advances in molecular biology have led to highly safe, efficient, and effective platforms, such as mRNA, that can be rapidly re-purposed for different pathogens, multiple pathogens, or new strains of evolving pathogens. 2023 Jul 6; Available from: [link] Mora C, McKenzie T, Gaw IM, et al. 2023 [cited 2024 Jan 22].

Drug Development 122

Drug Development Virus Vaccine Drugs 122

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Link Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology, by Hughes R.A. & Cold Spring Harbor Perspectives in Biology. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition. Science (2023).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Science (2023).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Broad Institute

JANUARY 7, 2025

From her first biology course in high school, Rehm loved the logic of genetics: the clear trajectory from a simple code of DNA to RNA to proteins and how disrupting that process could lead to disease. Rehm and others continue to improve these guidelines.

Disease 121

Disease Science Laboratories Medical Schools 121

BMG Labtech

FEBRUARY 24, 2025

Protein nitration assays are widely used in many research areas including but not limited to biochemistry , biotechnology , cell biology , microbiology , and molecular biology. 2023 Mar 21;12(6):2411. Czarnecka AM, Obara-Michlewska M, Wes-Kucharska D, Greczan M, Kaczor M, Ksiyk J, Rokicki D, Zieliska M. J Clin Med.

Small Molecule 52

Small Molecule Disease Licensing Licensing 52

Codon

MAY 29, 2025

His fascination with toxic organisms began during childhood explorations in Minnesota's boreal forest and has taken him from the Galápagos Islands for his dissertation research to the molecular biology laboratories of Harvard, and eventually Berkeley, where he studies how species evolve to produce and resist deadly chemicals.

Drugs 108

Drugs DNA RNA Laboratories 108

Codon

JANUARY 8, 2025

Anecdotal examples of this have already been published; for example, Carnegie Mellon scientists released Coscientist in 2023, a robot hooked up to ChatGPT that designs its own chemistry experiments to synthesize molecules. Whether or not a similar robot could work for biology , however, remains to be seen.

Science 63

Science Vaccine Engineering Disease 63