Codon

APRIL 17, 2025

Plastic leaves do not emit organic signals and contain no DNA, so any mimicry could imply some kind of primitive vision. Such vascular differences are governed by auxin, a plant hormone that regulates leaf venation and shape. ” Asimov Press (2025). He is from Palo Alto and is currently based in Los Angeles.

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Broad Institute

JUNE 24, 2025

By Broad Communications June 24, 2025 Credit: Casey Atkins David Liu is a core member at the Broad Institute where he is the Richard Merkin Professor and director of the Merkin Institute for Transformative Technologies in Healthcare. Some of these treatments, like K.J.’s,

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Codon

JUNE 5, 2025

Certain CRISPR components can add short DNA sequences from the genomes of defeated viruses into the bacterium’s own genome, creating a type of protective “memory.” If the same virus invades the cell a second time, the gRNA’s spacer sequence will bind to the matching viral DNA sequence, then be cut by the Cas protein.

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Agency IQ

AUGUST 11, 2023

Since this discovery, it’s been unclear how regulators or sponsors might assess or address these potential risks. Clearly, the scope of the issue has grown substantially compared to what was covered in the initial guidances and AI recommendations provided by regulators in the last several years. “To ensure the safety of the U.S.

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Broad Institute

MAY 29, 2025

New technique expands cells to sequence DNA and capture fine structural details By Allessandra DiCorato May 29, 2025 Breadcrumb Home New technique expands cells to sequence DNA and capture fine structural details Using this method, scientists discovered key protein and gene activity changes in aging and in a rare disease called progeria.

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Codon

MAY 8, 2025

If so, then here's a question: How much information is in your DNA? When I first looked into this question , I thought it was simple: Human DNA has about 3.1 Each base pair can take one of four values (A, T, C, or G) It takes 2 bits to encode one of four possible values (00, 01, 10, or 11) Thus, human DNA contains 6.2

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Broad Institute

MAY 12, 2025

By Allessandra DiCorato May 12, 2025 Credit: Allison Colorado, Broad Communications A fellow in Broad's Gene Regulation Observatory, Bo Xia studies how the structure of the genome determines cell fate in both health and disease. In school, he loved imagining how molecules made up materials and whole organisms.

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DNA Regulations Cell Biology Disease 81

Codon

FEBRUARY 19, 2025

The same model can also generate brand-new DNA sequences at the scale of yeast chromosomes or small bacterial genomes. AI Architectures Before explaining how Evo 2 could make bioengineering more predictable, it helps to first understand how AI models actually “learn” the language of DNA.

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Broad Institute

MARCH 27, 2025

A Novo Nordisk - Broad collaboration is connecting Denmark-based and Broad researchers By Corie Lok March 27, 2025 Breadcrumb Home A Novo Nordisk - Broad collaboration is connecting Denmark-based and Broad researchers The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease has built a bridge between Danish and Broad scientists.

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Codon

APRIL 24, 2025

We’re close to selling out of our second book —written in both text and DNA—and we recently launched a merchandise store. The reason for this shift is relatively simple: Chinese regulators have passed reforms that lower barriers to market entry and streamline approvals. ” Asimov Press (2025).

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Codon

APRIL 10, 2025

That’s astonishingly small, roughly equal to the weight of the DNA inside a single hummingbird cell. The other 30 percent — the so-called “dry mass” — is composed of everything else: DNA, RNA, proteins, lipids, and ions. Similar considerations apply for DNA, RNA, and all the other molecules, too.

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Agency IQ

MARCH 29, 2024

What we expect the EPA to do in April 2024 The top line: In this returning feature, AgencyIQ looks at public data to determine what the EPA is planning to do in the month ahead, including deadlines, meetings, events, planned regulations, comment periods, and more. PFAS regulations for drinking water.

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Regulations Compliance Production Government 40

Broad Institute

MAY 13, 2025

AI tool predicts potential drug targets by analyzing cell images By Corie Lok May 13, 2025 Breadcrumb Home AI tool predicts potential drug targets by analyzing cell images Researchers have developed a machine learning model that connects images of DNA structure to gene regulation. Online May 12, 2025. Cell Systems.

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LifeSciVC

MAY 28, 2025

But with the rise of Chinas innovative sector, the proliferation of biologic drugs coded by DNA, and more than dozen years of abundant capital, to name just a few things – the challenge has only gotten worse. As illustrated in LEKs May 2025 report Is Biopharma Doing Enough to Advance Novel Targets ?

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Drug Target Review

MAY 8, 2025

While reducing mutant huntingtin is desirable, the wild-type huntingtin protein plays crucial roles in normal neuronal function, including vesicular transport, synaptic function and transcriptional regulation. Accessed March 2025. Accessed March 2025. Huntington’s Disease Society of America. ” HDSA.org.

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Codon

MAY 15, 2025

Random mutations in DNA bring about this genetic variation, and mating between unrelated individuals mixes the mutations amongst the population. Most vertebrates in the study, including the lab mouse, Mus musculus , acquire one mutation for every 100 million DNA bases per generation. percent of the mouse’s DNA.

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BioPharma Drive: Drug Pricing

JUNE 9, 2025

Originally designed to regulate blood sugar in type 2 diabetes, GLP-1 receptor agonists have evolved into groundbreaking treatments for obesity, cardiovascular disease and even neurodegenerative conditions. By Ben Fidler • March 4, 2025 Permission granted by Daiichi Sankyo ASCO25 Daiichi Sankyo struck gold with ‘ADC’ cancer drugs.

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BioPharma Drive: Drug Pricing

JUNE 5, 2025

Published June 5, 2025 Amy Baxter Staff Reporter post share post print email license FDA Commissioner Martin Makary attends a Senate Appropriations Committee hearing May 22, 2025. While it offered the first look at a possible framework for how pharmas using AI will be evaluated by regulators, many AI experts want more details.

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Codon

MAY 29, 2025

The insulin released into the water is a near-perfect molecular match of the insulin produced by the fish to regulate their blood sugar, an example of convergent evolution, or the re-evolution of the same trait in different species. After entering the cell, CdtB acts like a DNA scissors and cuts the molecular threads.

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Codon

DECEMBER 1, 2024

Many students are taught that the Central Dogma is simply “DNA → RNA → protein.” In 1956, Crick was working on a lecture that would bring together what was then known about the “flow of information” between DNA, RNA, and protein in cells.

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RNA DNA Molecular Biology Virus 134

Codon

FEBRUARY 9, 2025

The connection between the destroyed lobe and Gage’s reduced capacity for emotional regulation was stark. Metagenomics, for example, allows scientists to build extensive reference libraries of DNA for use in everything from the creation of vital medicines to CRISPR tools. ” Asimov Press (2025). Cite: Balwit X.

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Codon

MAY 12, 2025

Proteins and DNA usually unravel in such scalding environments, yet researchers who descended in submarines in 1982 found entire colonies thriving at these extreme temperatures. They also shield their genomes using an enzyme called reverse gyrase , which burns ATP energy molecules to wrap DNA in a heat-protective supercoil.

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