Science Daily: Pharmacology News

JANUARY 16, 2025

Two new articles document progress in neuroprosthetic technology that lets people feel the shape and movement of objects moving over the 'skin' of a bionic hand.

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Science Daily: Pharmacology News

JANUARY 28, 2025

A new article argues that by relying too much on parsimony in modeling, scientists make mistakes and miss opportunities.

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Science Daily: Pharmacology News

JULY 10, 2024

The most complete dinosaur discovered in the UK in the last 100 years, with a pubic hip bone the size of a 'dinner plate', has been described in a new article.

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Research 285

Science Daily: Pharmacology News

JULY 23, 2024

The insecticide-treated bed nets and insecticide sprays that were so effective in preventing mosquito bites -- and therefore malaria -- are increasingly viewed as the causes of household pest resurgence after pests became resistant to pesticides, according to a new article.

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Science Daily: Pharmacology News

SEPTEMBER 25, 2024

The SAGA Survey just published three new research articles that provide us with new insights into the uniqueness of our own Milky Way Galaxy after completing the census of 101 satellite systems similar to the Milky Way's.

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Research 280

Science Daily: Pharmacology News

JULY 29, 2024

Now, an interdisciplinary team of scientists has produced a perspective article of this co-evolutionary history. The atmosphere, the ocean and life on Earth interacted over the past 500-plus million years in ways that improved conditions for early organisms to thrive.

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Science Daily: Pharmacology News

JULY 1, 2024

This conclusion comes from researchers who reviewed over 300 scientific articles from many different fields of research. Human hunting, not climate change, played a decisive role in the extinction of large mammals over the last 50,000 years.

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Research 290

Science Daily: Pharmacology News

JANUARY 27, 2025

But you might want to change that if you want to improve your health and well-being, according to a new review article. Even if you did, it's highly likely you didn't fully unplug while off the clock.

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Science Daily: Pharmacology News

JUNE 27, 2024

A new article shows how specific physical conditions -- especially ocean viscosity and resource deprivation -- during the global glaciation period known as Snowball Earth could have driven eukaryotes to turn multicellular.

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Science Daily: Pharmacology News

JUNE 25, 2024

A review article of the available studies directly comparing the impact of plant-based and animal-based meats consistently suggests that the plant-based alternatives improve cardiovascular risk factors.

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Science Daily: Pharmacology News

DECEMBER 20, 2023

But a new study by a team of researchers shows the opposite occurs: Searching to evaluate the truthfulness of false news articles actually increases the probability of believing misinformation. Conventional wisdom suggests that searching online to evaluate the veracity of misinformation would reduce belief in it.

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Research 275

Chemical Biology and Drug Design

APRIL 4, 2025

Therefore, this article first summarizes terms of IDH1 function from the molecular mechanism of IDH1, the mechanism of mutation, and the metabolism of substances due to mutations. In addition, this article introduces representative mIDH1 inhibitors according to the differences of mutation sites.

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Small Molecule Drugs DNA Treatment 100

Science Daily: Pharmacology News

OCTOBER 4, 2023

A research article presents a significant breakthrough in the area of skin regeneration and wound healing.

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Research 242

Chemical Biology and Drug Design

MAY 12, 2025

This article outlines the current antiretroviral therapy and its adverse effects but also CRISPR/Cas technology. This review article also discusses its mechanism of action and potential applications in the treatment of HIV/AIDS. Furthermore, it enhances our understanding of fundamental genetics.

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Treatment Therapies DNA RNA 100

Chemical Biology and Drug Design

MARCH 26, 2025

In this article, we present the synthesis of novel 3-phenyl-1-((1-aryl-1 H -1,2,3-triazol-5-yl)methyl)spiro[indoline-3,2-oxiran]-2-one derivatives by the regioselective reaction of sulfur ylides with 1,2,3-triazole-tethered isatins and their anticancer effects on hepatocellular carcinoma (HCC) cells HepG2 and HCCLM3.

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Research 100

Chemical Biology and Drug Design

NOVEMBER 4, 2024

This review article comprehensively summarized the recent advancements in galantamine and its hybrid analogs as potential therapeutic agents for the management of AD. Alzheimer's disease (AD) is a progressive age-related neurodegenerative brain disorder that destroys memory and other important mental functions.

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Disease Therapies Research 100

Science Daily: Pharmacology News

SEPTEMBER 8, 2023

A new article hints at the existence of several black holes in the Hyades cluster -- the closest open cluster to our solar system -- which would make them the closest black holes to Earth ever detected.

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Drug Patent Watch

NOVEMBER 26, 2024

This article delves into the intricate world of drug repurposing… Source In the ever-evolving landscape of pharmaceutical research and development, drug repurposing has emerged as a promising strategy to bring new treatments to patients more quickly and cost-effectively.

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Drugs Pharmaceuticals Treatment Research 96

Science Daily: Pharmacology News

SEPTEMBER 1, 2023

The many environmental responses to the Arctic dipole are described in a recent article. The findings indicate that stronger declines in sea ice will occur when an atmospheric feature known as the Arctic dipole reverses itself in its recurring cycle. This analysis helps explain how North Atlantic water influences Arctic Ocean climate.

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Science Daily: Pharmacology News

JANUARY 31, 2024

coli is described in a new article. A new type of E. coli that is both highly infectious and resistant to some antibiotics has been discovered. The newly identified mutation of antibiotic-resistant E. The team suggests that some existing antibiotics called carbapenems will be ineffective against the bacteria.

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Science Daily: Pharmacology News

APRIL 22, 2025

A powerful clinical artificial intelligence tool developed by biomedical informatics researchers has demonstrated remarkable accuracy on all three parts of the United States Medical Licensing Exam (Step exams), according to a new article.

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Science Daily: Pharmacology News

SEPTEMBER 29, 2023

Now, an article challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice.

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Drug Patent Watch

DECEMBER 4, 2024

This article will explore how machine learning can be leveraged to optimize generic drug development… Source These methods have the potential to revolutionize the drug discovery process by enhancing the efficiency and accuracy of identifying and developing new drug candidates.

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Drug Development Drugs Pharmaceuticals 92

Science Daily: Pharmacology News

SEPTEMBER 27, 2023

A new article has analyzed another understudied behavior in baleen (filter-feeding) whales such as humpback whales in different populations across the northern and southern hemispheres. They appeared to roll around and 'play' with clumps of kelp and seaweed at the water's surface.

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Research 215

Drug Patent Watch

NOVEMBER 11, 2024

This article explores key best practices and strategies for optimizing drug patent… Source Effective management of drug patent portfolios is crucial for pharmaceutical companies to maintain market exclusivity, protect revenue streams, and drive innovation.

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Pharmaceutical Companies Drugs Pharmaceuticals Marketing 102

Chemical Biology and Drug Design

MAY 10, 2025

The review focused on English-language original research and review articles, examining carprofen and its derivatives in terms of their synthesis methods as well as their use as small molecules in various therapeutic applications, both human and veterinary.

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Small Molecule Drug Development Science Therapies 100

Science Daily: Pharmacology News

APRIL 15, 2025

A new journal article examines how the study of seals in particular can benefit human health, and synthesizes various research on the topic.

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Nurses Research 147

Drug Patent Watch

DECEMBER 8, 2024

In this article, we will delve into the strategies and considerations for handling drug patent… Source However, with the increasing competition from generic and biosimilar manufacturers, patent invalidity claims have become a significant challenge for pharmaceutical companies.

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Biosimilars Pharmaceutical Companies Drugs Pharmaceuticals 96

Drug Patent Watch

MAY 14, 2025

In this exclusive article, we delve into the complex web of PBM's and their impact on the pharmacy landscape. That's essentially the world of Pharmacy Benefit Managers (PBMs) in the pharmaceutical industry. From opaque pricing to hidden fees, discover how PBMs are disrupting the delicate balance of the pharmaceutical supply chain.

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Pharmacy Pharmaceuticals 78

Drugs.com

JUNE 21, 2023

This article will explore the causes of back spasms, their symptoms and, most. WEDNESDAY, June 21, 2023 -- "Oh, my aching back!" Everyone has uttered these words at some point, in response to the sharp, sudden pain that comes with back spasms.

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Chemical Biology and Drug Design

FEBRUARY 15, 2024

This article highlights the various structural features along with the structure–activity relationship (SAR) of nitrogen-containing heterocyclics that play a key role in binding at target sites for potential antidepressant action.

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Drugs Research 189

Science Daily: Pharmacology News

AUGUST 28, 2023

A new article describes the 266 fossil species as one of the richest and most diverse groups of three-million-year-old fauna ever found in New Zealand. At least ten previously unknown species will be described and named in future research.

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Treatment Research 189

Covalent Modifiers

JUNE 29, 2024

Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard J. van Westen, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, and Daan van der Es ACS Chemical Biology 2024 DOI: 10.1021/acschembio.4c00210 4c00210 Small molecular tool compounds play an essential role in the study of G protein-coupled receptors (GPCRs).

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Crown Bioscience

JUNE 23, 2025

This article explores the role in vitro models are playing in the fight against drug resistance and explains how they can accelerate the development of successful novel therapies.

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Drugs Drug Development Therapies Treatment 52

Science Daily: Pharmacology News

JUNE 27, 2023

In a pair of articles, they report that, in experiments with flakes of semiconductor materials -- each only a single layer of atoms thick -- they detected signatures of 'fractional quantum anomalous Hall' (FQAH) states. Scientists and engineers have announced a significant advancement in developing fault-tolerant qubits for quantum computing.

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Covalent Modifiers

SEPTEMBER 22, 2024

link] The article presents the discussion on interaction of covalent inhibitors GW9662 and T0070907 with the peroxisome proliferator-activated receptor gamma (PPARγ), revealing new insights into how these compounds influence receptor activity. Andrew D Huber, Taosheng Chen eLife 2024, 13 :e101446.

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Regulations 162

Covalent Modifiers

JANUARY 13, 2024

This article discusses the genesis of the burgeoning field of catalytic inhibitors, the current state of the art, and exciting future directions.

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Small Molecule International Disease Drugs 195