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Genomic score predicts patients' progression to multiple myeloma

Broad Institute

In the future, the MM-like score could be used in clinical practice to inform decisions about early intervention. This study brings us closer to more personalized care for patients with a precursor stage of cancer and could better inform early intervention strategies in the future. The study was published in Nature Genetics.

DNA
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What single cells are revealing about brain disorders

Drug Target Review

I got my eyes opened to molecular biology, bioinformatics, computational biology and these emerging fields at the time.” Before joining 10x Genomics, Michael was a NSF postdoctoral fellow with Eric Lander at the Broad Institute, where he worked on developing novel applications of DNA sequencing technologies.

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Breaking Barriers in Solid Tumor Research: Precision Medicine & Strategic Operations

Conversations in Drug Development Trends

Liquid biopsies, particularly those that detect circulating tumor DNA amongst other known blood-based biomarkers, make the screening process less invasive and more approachable to patients who already undergo multiple blood draws daily, reducing participation burden.

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What Makes a Mature Science

Codon

Dwarves aren’t made out of individual cells; they don’t have DNA (yet), though they do have eyelids. “Our Microscope informs us that the substance of Cork is altogether fill'd with Air,” he wrote, “perfectly enclosed in little Boxes or Cells distinct from one another.” A mature science, this was not.

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Boehringer Ingelheim and Twist Bioscience Enter Therapeutic Antibody Discovery Collaboration

The Pharma Data

By leveraging our unique ability to manufacture DNA at scale, we can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

DNA
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A scientist devotes her career to tackling inequity in genomics

Broad Institute

At the Broad, Martin is also helping lead data analysis in two large international studies that are sequencing the DNA of people from Africa and Latin America to learn about the genetics of severe mental illness. Alicia Martin and attendees of the KEMRI-Wellcome Trust/GINGER Bioinformatics training in Kilifi, Kenya in September 2018.

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Next Generation Sequencing (NGS): why is quantifying nucleic acids important? | BMG LABTECH

BMG Labtech

These numbers reflect impressive developments in DNA sequencing technologies but in most cases represent the immediate costs of consumables on the sequencing instrument. 2 DNA sequencing is also reliant on sample processing and DNA library preparation before sequencing as well as bioinformatics and data analysis after sequencing.

DNA