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Scientific workflow for hypothesis testing in drug discovery: Part 1

Drug Target Review

Based in South Africa, she has worked extensively with international biotech companies, specialising in therapeutic development for aging-related diseases and complex conditions such as glioblastoma and Autosomal Dominant Polycystic Kidney Disease (ADPKD).

RNA 52
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Why Mallory Freeberg is creating a perturbation catalogue

The Open Targets Blog

Mallory Freeberg leads the Human Genomics Team at EMBL’s European Bioinformatics Institute (EMBL-EBI), and is one of the leads of the Perturbation Catalogue, an Open Targets project which aims to bring genetic perturbation data into one curated, harmonised, and discoverable platform, hosted at EMBL-EBI.

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From siloed data to breakthroughs: multimodal AI in drug discovery

Drug Target Review

Internally, the models learn to associate concepts, find patterns and relate text and images (or other modalities) so that they can be analysed in the same way. Each modality represents a different type of data, such as text, audio, images, video, and more. The most common MLMs are GPT-4o (powering the free ChatGPT tier), Gemini 1.5

Drugs 65
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Genomic score predicts patients' progression to multiple myeloma

Broad Institute

Adelson Medical Research Foundation, the International Myeloma Society, Dana-Farber Cancer Institute, the Krouse Family Foundation, the National Cancer Institute, and Stand Up to Cancer. These insights wouldn't be possible without access to deeply sequenced whole genomes from a large number of patients and across different disease stages."

DNA 52
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Solving the disconnect between lab and data scientists: part 1

Drug Target Review

I began in bioinformatics, conducting lab-based genomics work but soon felt the need to dive deeper into the computational side. IK: At recent conferences, including the international SLAS conference in San Diego and Europe , we’ve held meetings for our interest group.

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Therapeutic Oligos 2025 Keynote Speakers Announced

Elrig

Prof Rory Johnson is an Associate Professor at University College Dublin, where his research focusses on uncovering the roles of long noncoding RNAs (lncRNAs) in human health and disease using an interdisciplinary combination of bioinformatic and experimental methods.

RNA 59
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Solving the disconnect between lab and data scientists: part 2

Drug Target Review

Gaining lab experience is more difficult without institutional access, which is why I’d encourage computer science students interested in pharma or life sciences to intern or volunteer in campus labs early in their education. That hands-on experience helps create a more well-rounded professional.