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Time for change: non-human primates in drug research

Drug Target Review

Guide for the Care and Use of Laboratory Animals. NIH Office of Laboratory Animal Welfare – Training Guidelines. Alternatives to Laboratory Animals , 50(3). Conventional models often fail to predict cardiac side effects, especially with biologics. Federal ruling on USDA primate welfare petition, 2023. National Research Council.

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Levers for Biological Progress

Codon

Amodei also imagines the ways AI could accelerate biological research and yield miraculous cures in the 21st century; everything from the prevention and treatment of nearly all infectious and inherited diseases to the elimination of most cancers. ” Nobody really knows without trying it out in the laboratory. Even the humble E.

DNA 132
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Condensate biology: advancing drug discovery for complex diseases

Drug Target Review

In this article, we will delve into the world of condensate biology and explore the groundbreaking research projects undertaken to discover the potential they hold for diseases such as amyotrophic lateral sclerosis ( ALS ) and colorectal cancer. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98
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#ScienceSaturday: March 2, 2024

KIF1A

Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. Animal models have given researchers profound insights into disease, assisting in the creation and testing of new therapies that have changed lives across the world.

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New molecular insights on medical cannabis

Drug Target Review

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. The Journal of Cell Biology. 2002 Jul 22;158(2):227–33.

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CAR-NK cells: promising for cancer therapy

Drug Target Review

They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells). NK cells can be readily extracted from umbilical cord blood or peripheral blood of adult donors.

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A New Type of Bookworm: Bringing Patient Perspectives Into the Classroom?

KIF1A

In this blog post, KIF1A.ORG Chief Science Officer Dr. Dominique Lessard describes a unique cross disciplinary experience with multiple scientific stakeholders in the rare disease space, all focused around our holistic understanding of KAND. How do we move the needle to make patient voices and experiences the center of scientific discovery?

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