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Researchers devise new way to target and correct disease-related proteins

Broad Institute

Also featured are the FKBP12 binding motif (light blue triangle), the DNA barcode (red double helix), and the combinatorial library element (red hexagon). Related groups Xavier lab Over the past two decades, large genetic studies have linked tens of thousands of DNA variants to thousands of human traits and diseases.

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New study aims to uncover the genetics of anorexia and other eating disorders

Broad Institute

Researchers at the Broad Institute Ben Neale and Mark Daly are co-leading the study, which allows people across the US to sign up to have their DNA analyzed as part of this effort. The team then sequences the DNA using an approach called the Blended Genome Exome , an efficient and cost-effective alternative to whole-genome sequencing.

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Cancer-Causing Culprits Will Be Caught By Their DNA Fingerprints

Drug Discovery Today

Causes of cancer are being catalogued by a huge international study revealing the genetic fingerprints of DNA-damaging processes that drive cancer development.

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Scientists create next generation of tools in battle against brain disease

Broad Institute

The team has successfully created over 1000 of them, and each consist of: a harmless adeno-associated virus (or AAV) that acts like a shuttle capable of transporting specially designed DNA into the cell; a segment of DNA (an enhancer) that acts like an activation switch to mark or trigger a change in how the cell functions.

Disease 72
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New tRNA tech aims to rewrite rare disease treatment

Drug Target Review

“Unlike gene editing, which makes irreversible DNA changes, engineered tRNA allows for controlled, reversible interventions,” Michelle highlights. “A A single tRNA therapeutic could treat multiple diseases caused by the same mutation.”

Disease 80
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Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. Gerstner, Jr., to advance technologies that could transform cancer care

Broad Institute

Liquid biopsies enable clinicians to find and analyze tumor DNA in a patient’s blood sample to detect cancer early, monitor cancer recurrence, assess the patient’s response to treatment, and measure other clinically important features in real time, without invasive procedures. "We

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#ScienceSaturday: April 6, 2024

KIF1A

When a mutation causes a deletion or duplication of larger areas of DNA, we call it Copy Number Variation. DNA deletion and duplication may impact large sections of genes, or multiple neighboring genes. The altered expression of so many genes has profound consequences for the nervous system. She graduated from UC San Diego with a B.S.

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