Drug Discovery World

JUNE 5, 2024

UK charity LifeArc has pledged £1.5 million to fund a new two-year collaborative partnership with King’s College London (KCL) to validate a portfolio of human genetic driven therapeutic targets for motor neuron disease (MND). The new partnership, which will involve scientists from both organisations working closely together, is part of LifeArc’s MND Translational Challenge, aimed at discovering innovative and potentially disease-modifying treatments for MND, a key component of the new UK MND Res

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Bioinformatics Research Drugs Clinical Trials 173

Science Daily: Pharmacology News

JUNE 5, 2024

A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

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Disease 132

Drug Discovery World

JUNE 5, 2024

Developing new drugs is a complex and often lengthy process. A major roadblock lies in the limitations of traditional preclinical models, which often fail to accurately represent the intricate biology of human patients. Join DDW for a free event on 18 June, 3PM BST to learn more about how patient-derived organoids are revolutionising drug discovery.

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Laboratories Disease Regulations Drug Development 130

Science Daily: Pharmacology News

JUNE 5, 2024

Eating a poor quality diet might lead to brain changes that are associated with depression and anxiety. This is according to a first-of-its-kind study into the brain chemistry and structure, and diet quality of 30 volunteers.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

BioPharma Drive: Drug Pricing

JUNE 5, 2024

How can small and mid-sized biotech companies better manage pharmacovigilance during clinical trials? Listen to the podcast to learn how strategic alliances are helping.

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Production Clinical Trials Trials 128

Science Daily: Pharmacology News

JUNE 5, 2024

Diabetes rates continue to rise. Scientists have now created a pain-free drug delivery method to help people with diabetes manage the disease and maintain their health more easily. Researchers have developed oral insulin drops that when placed under the tongue are quickly and efficiently absorbed by the body, potentially replacing the need for insulin injections.

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Disease Research Drugs 125

Science Daily: Pharmacology News

JUNE 5, 2024

Blood stem cells -- key to transplants that are used as life-saving treatments for blood cancers and blood and immune disorders -- have the capacity to self-renew, but quickly lose their ability to do so in a lab dish. Scientists have identified a protein that not only enables blood stem cells to self-renew in a lab dish, but also allows these expanded cells to function effectively after being transplanted into mouse models.

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Therapies Treatment 121

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- In new guidelines released Tuesday, U.S. health officials now recommend that certain people take the antibiotic doxycycline as a morning-after pill to lower the risk of some sexually transmitted diseases (STDs). The.

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Disease 116

Science Daily: Pharmacology News

JUNE 5, 2024

Researchers have developed a low-cost, energy-efficient method for making materials that can capture carbon dioxide directly from the air. Researchers used a method similar to charging a battery to instead charge activated charcoal, which is often used in household water filters.

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Research 119

NIOSH Science Blog: Drugs

JUNE 5, 2024

Each June, we bring a little extra attention to safety issues by highlighting National Safety Month®. For each week of the month, the National Safety Council (NSC) identifies a theme to focus on. This blog highlights select research and prevention efforts from the National Institute for Occupational Safety and Health (NIOSH) and NSC in this year’s focus areas of safety engagement; roadway safety; risk reduction; and slips, trips and falls.

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Research 112

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

JUNE 5, 2024

Large Language Models behind popular generative AI platforms like ChatGPT gave different answers when asked to respond to the same reasoning test and didn't improve when given additional context, finds a new study.

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Fierce BioTech

JUNE 5, 2024

Drive or take the metro in any direction within Montgomery County, Maryland, and you'll come across a life science company responsible for a major innovation. | Drive or take the metro in any direction within Montgomery County, Maryland, and you'll come across a life science company responsible for a major innovation.

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Science 106

Science Daily: Pharmacology News

JUNE 5, 2024

Babies' brains are not as immature as previously thought, rather they are using the period of postnatal 'helplessness' to learn powerful foundation models similar to those underpinning generative Artificial Intelligence, according to a new study.

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Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- Drug-resistant fungal infections are appearing in the United States, resulting in highly contagious and tough-to-treat cases of ringworm, also known as jock itch or athlete's foot, experts warn in a pair of reports. The.

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Drugs 105

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

JUNE 5, 2024

A new clinical trial of five children with inherited deafness found administering gene therapy in both ears led to restored hearing and speech, and additional gains including sound source localization, ability to hear in noisy environments, and for two children, abillity to appreciate music. This is the first trial in the world to treat children with hereditary deafness in both ears with gene therapy.

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Therapies Trials Clinical Trials International 115

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- Chlidren born deaf have had their hearing restored in both ears as a result of gene therapy, a new study reports.All five children showed hearing recovery in both ears, with dramatic improvements in speech perception and.

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Therapies 105

Science Daily: Pharmacology News

JUNE 5, 2024

A rare exoplanet that should have been stripped down to bare rock by its nearby host star's intense radiation somehow grew a puffy atmosphere instead -- the latest in a string of discoveries forcing scientists to rethink theories about how planets age and die in extreme environments. Nicknamed 'Phoenix' for its ability to survive its red giant star's radiant energy discovered planet illustrates the vast diversity of solar systems and the complexity of planetary evolution -- especially at the end

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Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- A U.S. Food and Drug Administration advisory panel on Tuesday voted against recommending the psychedelic MDMA for the treatment of post-traumatic stress disorder (PTSD).In a 10-1 vote, the panel determined the evidence.

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Treatment FDA Drugs 103

Science Daily: Pharmacology News

JUNE 5, 2024

Bronze cauldrons were used by the inhabitants of the Mongolian steppe around 2,700 years ago to process animal blood and milk. This is shown by a protein analysis of archaeological finds from this period.

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Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- Teens on the verge of falling asleep behind the wheel is a common threat to public safety on U.S. roadways, a new study reports.About 1 in 6 teenage drivers say they’ve driven while drowsy, according to a National Sleep F.

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Science Daily: Pharmacology News

JUNE 5, 2024

Geobiologists reported a 550 million-year-old sea sponge that had been missing from the fossil record. The discovery sheds new light on a conundrum that has stumped zoologists and paleontologists for years.

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Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- Military veterans often struggle with their mental health once their service ends, but the first clinical trial of its kind has found that having a service dog helps lower the risk of PTSD for these former.

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Clinical Trials Trials 98

Science Daily: Pharmacology News

JUNE 5, 2024

Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids.

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Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- Parents frustrated with kids who are seemingly glued to their phones, take heart: New research finds you can tear them away from their devices.Two approaches seem to work best: Limiting screens during meals or bedtime.

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Research 98

Science Daily: Pharmacology News

JUNE 5, 2024

Fusion researchers have successfully deployed machine learning methods to suppress harmful plasma edge instabilities without sacrificing plasma performance.

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Research 89

Drugs.com

JUNE 5, 2024

THURSDAY, June 6, 2024 -- Many women are unhappy with the state of U.S. maternal health care, but a major new poll finds most Americans don’t understand how badly the nation lags behind other wealthy countries in this area. Only about 2 in 5.

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Science Daily: Pharmacology News

JUNE 5, 2024

Researchers are adding a new wrinkle to a long-held belief about what causes earthquakes in the first place.

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Research 101

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- In new guidelines released Tuesday, U.S. health officials now recommend that certain people take the antibiotic doxycycline as a morning-after pill to lower the risk of some sexually transmitted diseases (STDs).The.

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Disease 98

Drug Target Review

JUNE 5, 2024

What is the effectiveness of R327 against the full suite of ESKAPE pathogens in independent bacterial efficacy studies? R327 was studied against several Gram-negative and Gram-positive microbial species, including the ESKAPE pathogens, a group of highly resistant bacteria and the leading cause of hospital-acquired infections globally. These include E nterococcus faecium , S taphylococcus aureus , K lebsiella pneumoniae , A cinetobacter baumannii , P seudomonas aeruginosa , and E nterobacter spec

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Pharmaceuticals Hospitals International Trials 72

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- Less than one-quarter of people who survive serious heart conditions receive the dietary counseling needed to protect their future health, a new study finds.Only about 23% of people treated for major illnesses like heart.

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Plenge Gen

JUNE 5, 2024

Disclaimer: I am a full-time employee of Bristol Myers Squibb. When I practiced clinical rheumatology, I would often see patients with autoimmune conditions like systemic lupus erythematosus (SLE), systemic sclerosis (scleroderma), rheumatoid arthritis (RA), or myositis. A typical patient journey included an initial sense of relief when a diagnosis was established and a medicine was started.

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Disease Drugs 69

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- As an epidemic of drug abuse cuts it way through America, none are left unharmed, even the very young.New data finds that the rate of infants dying from drug-related reasons more than doubled between 2018 and 2022.In.

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Drugs 98

BioPharma Drive: Drug Pricing

JUNE 5, 2024

A study abstract shed more light on tirzepatide’s potential in MASH. Elsewhere, Cytokinetics CEO spoke on deal negotiations and AbbVie started a key multiple myeloma drug study.

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Drugs 64

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- A woman who was the second person to ever receive a kidney from a genetically modified pig has had the transplanted organ removed due to complications linked to a heart pump she is using, her doctors said.Lisa Pisano, 54.

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