Science Daily: Pharmacology News

JULY 8, 2024

You look up into the clear blue sky and see something you can't quite identify. Is it a balloon? A plane? A UFO? You're curious, right? A research team has for the first time witnessed what is happening in the human brain when feelings of curiosity like this arise. The scientists revealed brain areas that appear to assess the degree of uncertainty in visually ambiguous situations, giving rise to subjective feelings of curiosity.

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Research 132

Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- Mounjaro outperforms Ozempic in helping people lose weight, a new study shows.People taking tirzepatide (Mounjaro, Zepbound) dropped significantly more pounds than those taking semaglutide (Ozempic, Wegovy), researchers.

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BioPharma Drive: Drug Pricing

JULY 8, 2024

The deal would hand Lilly an experimental pill that could one day rival Takeda's blockbuster medicine Entyvio as a treatment for inflammatory bowel disease.

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Science Daily: Pharmacology News

JULY 8, 2024

Scientists may have to rethink the relationship between the ocean's circulation and its long-term capacity to store carbon, new research suggests. As the ocean gets weaker, it could release more carbon from the deep ocean into the atmosphere -- rather than less, as some have predicted.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- Pancreatic cancer is particularly aggressive and difficult to treat, partly because it’s often resistant to chemotherapy.Researchers now think they know why chemo struggles to work against pancreatic cancer – and how to rev.

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BioPharma Drive: Drug Pricing

JULY 8, 2024

Acquiring Apeiron will hand Ligand rights to royalties on sales of the neuroblastoma drug Qarziba. Elsewhere, Aerovate said it’s considering strategic alternatives and CSL reported a notable milestone.

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Drugs 108

BioPharma Drive: Drug Pricing

JULY 8, 2024

Myricx Bio is developing a type of payload that it thinks could work in tumors resistant to the toxins contained in ADCs like Enhertu and Trodelvy.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- In yet another finding that touts the health benefits of wildly popular weight-loss medications like Wegovy and Ozempic, scientists report that taking the drugs may help reduce the risk of some cancers.In a study published.

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BioPharma Drive: Drug Pricing

JULY 8, 2024

Shares in HilleVax plummeted after the company reported its experimental shot failed to meet the primary and secondary goals of the Phase 2b study.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- Researchers report they have discovered lead and arsenic in a wide variety of tampon products sold in the United States and Europe. Testing revealed lead in all 30 tampons from 14 brands obtained from major online retailers.

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Clinical Trials

Science Daily: Pharmacology News

JULY 8, 2024

The largest animals do not have proportionally bigger brains -- with humans bucking this trend -- a new study has revealed.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- Exposure to air pollution can significantly reduce the odds of in vitro fertilization (IVF) leading to a live birth, a new study says.The odds of a live birth are nearly 40% lower in women heavily exposed to particle.

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Science Daily: Pharmacology News

JULY 8, 2024

An exoplanet infamous for its deadly weather has been hiding another bizarre feature -- it reeks of rotten eggs, according to a new study of data from the James Webb Space Telescope.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- An experimental cancer drug might be able to help prevent the organ damage caused by severe COVID infections, a new study finds.The drug, called eganelisib, inhibits an immune system enzyme called PI3K gamma that boosts.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

DrugBank

JULY 8, 2024

Revolutionizing Treatment Through the Skin with Transdermal Drug Delivery Systems The human skin, often perceived as a passive barrier to the external environment, holds potential as a route for drug administration. Transdermal drug delivery (TDD) systems offer a novel approach to drug delivery, by increasing therapeutic efficacy and increasing adherence to chronic disease management.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- Urinary incontinence is a common aftereffect of delivering a baby, but it can have a devastating effect on new moms, a new study warns.These bladder leaks are significantly associated with anxiety and depression in new.

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Drug Patent Watch

JULY 8, 2024

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 — Researchers have identified a gene that can trigger obesity, behavior problems and postpartum depression when missing or damaged.The finding could lead to new treatments for postpartum depression and overeating: The study in m.

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FDA Law Blog: Biosimilars

JULY 8, 2024

By Riëtte van Laack & JP Ellison — On Thursday, the 27 th of June, the Supreme Court issued its decision in Securities and Exchange Commission v. Jarkesy. The court ruled that the Securities and Exchange Commission (SEC) may not impose fines to penalize securities in its administrative proceedings because that practice violates the Seventh Amendment “right of trial by jury” in all “suits at common law.

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Agency IQ

JULY 8, 2024

BY ALEXANDER GAFFNEY, MS, RAC In this ongoing feature, AgencyIQ looks at public data to determine what the FDA is likely to do in the months ahead, including key deadlines, meetings, events, planned regulations, comment periods and more. The goal: To allow regulatory professionals to better anticipate and prepare for upcoming events and catalysts. Fill out the form to read the full article.

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Drug Patent Watch

JULY 8, 2024

Annual Drug Patent Expirations for VEKLURY Veklury is a drug marketed by Gilead Sciences Inc and is included in one NDA. It is available from one supplier.

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Agency IQ

JULY 8, 2024

BY WALKER LIVINGSTON, ESQ The Supreme Court has issued its opinion in Corner Post v. Board of Governors, holding that the law allows litigants to challenge agency regulations within six years of being harmed by those regulations, rather than six years from the time the agency finalized the regulations. This change, accompanied by other major Supreme Court cases this term, sets up the potential for a tidal wave of litigation against agencies in the coming years.

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Regulations 59

Drug Patent Watch

JULY 8, 2024

Annual Drug Patent Expirations for CONTRAVE Contrave is a drug marketed by Nalpropion and is included in one NDA. It is available from one supplier.

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Agency IQ

JULY 8, 2024

BY RACHEL COE, MSC Industry has been lobbying FDA and Congress to regulate medical gases different from other types of drug products since the 1970s. Nearly fifty years later, a final rule has made concessions industry has long been calling for, but retains reporting and safety provisions the agency deems important. Medical gases such as oxygen and medical air are widely used in a variety of healthcare and home/community settings.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- A diet rich in soy may help kids in the classroom, new research suggests.It found that 7- to 13-year-olds whose diets included more isoflavones were more attentive and had better thinking abilities. Soybeans and soy products.

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Agency IQ

JULY 8, 2024

BY SEBASTIAN GODOY, MPH , KIRSTEN MESSMER, PHD, RAC , COREY JASEPH, MS, RAC , KARI OAKES In this recurring feature, AgencyIQ, through public data and previous analysis, determines what European medicine and device regulators will likely do in the month ahead, including key deadlines, meetings, events, planned regulations, comment periods, and more. Given the expansive and complex European life sciences regulatory landscape, we’ll be including updates from key E.U. and national regulators.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 — After a mastectomy, some women are less likely than others to have breast reconstruction surgery.Rates of the surgery are consistently lower among American Indian and Alaskan native women than among non-Hispanic white women, a.

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Agency IQ

JULY 8, 2024

BY WALKER LIVINGSTON, ESQ The EPA has published a draft framework for an interagency collaboration on better understanding the impact of pesticides on the efficacy of human and animal drugs, with a specific focus on the effectiveness of antibacterial and antifungal drugs. Under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the EPA is responsible for the regulation of pesticides in the United States.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- Wartime appears to increase the risk of chronic pain for military women, a new study suggests.Active-duty servicewomen who served between 2006 and 2013 – a period of heightened combat deployments – had a significantly inc.

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Crown Bioscience

JULY 8, 2024

Immunotherapeutics are bringing remarkable survival rates for certain cancer patients, but they are also bringing some remarkable challenges for oncology drug developers. Evaluating immunomodulatory agents is more complex than assessing “common” chemotherapeutics or targeted agents. It requires preclinical models with an intact immune system (or at least functional aspects of the immune system targeted by a novel agent), which has led to the resurgence in use of syngeneic models.

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Drugs.com

JULY 8, 2024

MONDAY, July 8, 2024 -- An experimental drug can supercharge the effects of the lifesaving overdose drug naloxone, potentially improving its effectiveness against new and more powerful opioids like fentanyl, a new study finds.The drug, dubbed.

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Crown Bioscience

JULY 8, 2024

This post explores the fast-expanding topic of antibody-drug conjugates (ADCs), including those that have been approved to date and recent and future innovations that may come to bear on ADCs.

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Drugs 52

Perficient: Drug Development

JULY 8, 2024

Imagine a world where planning your dream vacation feels less like a chore and more like a conversation with a travel genie who knows exactly what you crave. This isn’t science fiction, but a reality being powered by generative AI. This transformative technology is rapidly reshaping the travel and tourism landscape, offering a wealth of opportunities for airlines, hotels, cruise lines, and all the experiences that make a trip unforgettable.

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Crown Bioscience

JULY 8, 2024

The DNA repair and DNA damage response (DDR) pathway is frequently disrupted in cancer and is one of the hallmarks of cancer. Germline and/or somatic mutations in critical DNA repair/DDR genes cause predisposition to cancer and higher mutational burden in cancers, respectively.

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