Thu.Sep 21, 2023

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We could sequester CO2 by 're-greening' arid lands, plant scientists say

Science Daily: Pharmacology News

Reducing CO2 levels in the atmosphere will take more than cutting emissions -- we will also need to capture and store the excessive volumes of already-emitted carbon. A team of plant scientists argue that arid lands such as deserts could be one answer to the carbon-capture problem.

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CDD Exhibiting and Presenting at Discovery on Target 2023, Boston, September 25-28

Collaborative Drug

Join CDD at Discovery on Target 2023, Sept 25-28. Explore CDD vault at Booth 209 and accelerate your product development.

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In Mississippi, a Huge Jump in Cases of Babies Born With Syphilis

Drugs.com

THURSDAY, Sept. 21, 2023 -- The United States is experiencing an alarming wave of congenital syphilis, and one southern state saw a 1,000% rise in babies born with the infection between 2016 and 2022. The number of babies born with the infection in.

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Scientists successfully maneuver robot through living lung tissue

Science Daily: Pharmacology News

Scientists have shown that their steerable lung robot can autonomously maneuver the intricacies of the lung, while avoiding important lung structures.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Helping Undocumented Immigrants Find a Primary Care Doc Lowers ER Costs: Study

Drugs.com

THURSDAY, Sept. 21, 2023 -- Helping undocumented immigrants in the United States connect with primary care doctors could be a money-saver, substantially reducing emergency department use and lowering health costs, a new study finds. The findings are.

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Suppressing Negative Thoughts Can Sometimes Be Healthy, Study Contends

Drugs.com

THURSDAY, Sept. 21, 2023 -- A longstanding core belief of mental health maintains that people must confront their fears to ease the anxiety and depression stemming from those negative thoughts.

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Scientists regenerate neurons that restore walking in mice after paralysis from spinal cord injury

Science Daily: Pharmacology News

In a new study in mice, researchers have uncovered a crucial component for restoring functional activity after spinal cord injury. The neuroscientists have shown that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.

Research 255
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Millions Are Exposed to Secondhand Smoke and Don't Know It

Drugs.com

THURSDAY, Sept. 21, 2023 -- A lot of people who think they don’t have secondhand smoke exposure actually do, according to a new study that compared survey answers with blood tests. According to the results of sensitive blood tests, more than half.

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Dinosaur feathers reveal traces of ancient proteins

Science Daily: Pharmacology News

Palaeontologists have discovered X-ray evidence of proteins in fossil feathers that sheds new light on feather evolution.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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U.S. Resumes Free COVID Test Program

Drugs.com

THURSDAY, Sept. 21, 2023 -- Americans will once again be able to get free at-home COVID tests. The U.S. Department of Health and Human Services (HHS) announced Wednesday that it will spend $600 million to buy and offer the tests, produced by 12.

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Conversations with plants: Can we provide plants with advance warning of impending dangers?

Science Daily: Pharmacology News

Plant scientists have engineered a light-controlled gene expression system (optogenetics system) from a prokaryotic system into a eukaryotic system that is tailored for plants.

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Today's COVID Is Increasingly Looking Like a Cold or Flu

Drugs.com

THURSDAY, Sept. 21, 2023 -- Symptoms of mild COVID-19 infection have shifted this season, and now are more akin to those of allergies and the common cold, doctors say. Many people with COVID-19 now are presenting with upper respiratory symptoms like.

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How climate warming could disrupt a deep-rooted relationship

Science Daily: Pharmacology News

Trees depend on fungi for their well-being. As climate change and global warming cause higher temperatures and amplified drought, little is known about how these important fungi will respond. To investigate this issue, a research team conducted a climate change experiment where they exposed boreal and temperate tree species to warming and drought treatments to better understand how fungi and their tree hosts respond to environmental changes.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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FDA Must Crack Down on Retailers Selling Tobacco to Teens: Report

Drugs.com

THURSDAY, Sept. 21, 2023 -- A new government report finds that federal regulators need to do more to help in the battle to keep kids and teens off tobacco. Among the report’s findings were that the U.S. Food and Drug Administration needs to get.

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No shortcuts: New approach may help extract more heat from geothermal reservoirs

Science Daily: Pharmacology News

Geothermal heat offers a promising source of renewable energy with almost zero emissions, but it remains a relatively expensive option to generate electricity. A new technique may help prevent 'short-circuits' that can cause geothermal power plants to halt production, potentially improving the efficiency of geothermal power, the researchers said.

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Gun Injuries Rise as Neighborhoods Gentrify

Drugs.com

THURSDAY, Sept. 21, 2023 -- As working class neighborhoods gentrify, you'll likely see rents rise, pricey restaurants move in — and maybe also a rise in gunshot wounds, researchers say. In U.S. neighborhoods that gentrified, gun injuries were 62%.

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This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage

Science Daily: Pharmacology News

Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Wildfire Smoke Pollution a Growing Global Threat

Drugs.com

THURSDAY, Sept. 21, 2023 -- More people around the world are exposed to wildfire smoke that has the potential to harm human health, and their numbers are growing, new research finds. More than 2 billion people are exposed to at least one day of.

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Ritual use of human remains dating from the Neolithic

Science Daily: Pharmacology News

An international study has documented post-mortem bone modifications not linked to consumption.

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Cell therapy developer closes funding round to support diabetes program

BioPharma Drive: Drug Pricing

More than $50 million in venture funding has now gone into Seraxis, which is among a series of biotechs trying to fundamentally alter diabetes treatment.

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Babies May Leave Cells Behind That Help Mom Prepare for Future Pregnancies

Drugs.com

THURSDAY, Sept. 21, 2023 -- One pregnancy may leave behind microscopic souvenirs that prepare a mom's immune system for the next one, a new study suggests. Experts said the research, carried out in lab mice, offers new insights into a longstanding.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Intarcia’s diabetes drug-device combo voted down again by FDA panel

BioPharma Drive: Drug Pricing

The 19-member advisory committee unanimously voted against Intarcia in the review, citing cardiovascular and kidney safety concerns.

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Antibodies 101: Avoiding the Mouse on Mouse Mess in IHC

addgene Blog

Fighting with antibodies to produce immunohistochemistry images that are crisp, bright, and lacking in non-specific staining can be a challenge in the best of cases. But it can be particularly challenging when your only antibody option is from the same species as your tissue samples. The bad news: this situation is hard to avoid if your model system is a mouse, given the wealth of commercially available mouse monoclonal antibodies.

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Novo Nordisk parent backs cell therapy manufacturing facility

BioPharma Drive: Drug Pricing

The Novo Nordisk Foundation’s planned manufacturing facility will help both private companies and academic researchers develop new cell therapies.

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Talk of the Towne episode 08: ZERO Prostate Cancer

Antidote

Antidote’s podcast, Talk of the Towne , hosted by Antidote’s Senior Clinical Informatics Manager, Dr. Richard Towne, is an interview series featuring members of Antidote's partner network. During each episode, Rich and his guests take a closer look at particular therapeutic areas, the latest research developments, and specific pain points that impact the patient population.

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Data – The Lifeblood of Intelligence Automation

Perficient: Drug Development

With all the hype around artificial intelligence (AI), AI can feel complicated, distant, or foreign. But guess what? It’s not new news and it doesn’t need to be complicated; it’s just a revolution of how we leverage data! Let’s take a quick dive into the data-driven universe of AI (i.e., intelligence automation). This article breaks down how data powers intelligence automation.

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Possible adulticidal drugs for Onchocerca volvulus

Drug Target Review

Introduction I clearly remember an incident as a researcher, which kept happening, from my undergraduate research up till now. From endemic communities, samples including skin snips and onchocercoma were collected. The majority of people in endemic communities had at least one onchocercoma, it was discovered during the fieldworks. The stigma associated with the painless but unsightly flat bean-shaped onchocercoma has plagued these people, who are mostly low income earners.

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Film dosed drug patent expirations by year

Drug Patent Watch

This chart shows the patent expirations for film dosed drugs over the next decade. The term of drug patents varies. The basic term for a patent is 20 years from… The post Film dosed drug patent expirations by year appeared first on DrugPatentWatch - Make Better Decisions.

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Baicalein, a component of banxia xiexin decoction, alleviates CPT?11?induced gastrointestinal dysfunction by inhibiting ALOX15?mediated ferroptosis

Chemical Biology and Drug Design

Baicalein may be one of the main components of banxia xiexin decoction acting as a palliative agent in CPT-11-induced delayed diarrhea and that the mechanism involves ALOX15-mediated inhibition of ferroptosis. Abstract Baicalein, one of the active ingredients of banxia xiexin decoction, has good therapeutic efficacy in treating diarrhea and improving gastrointestinal dysfunction.