Fri.Dec 20, 2024

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How AI will reshape pharma by 2025

Drug Target Review

Artificial intelligence (AI) has revolutionised many industries, yet its adoption in pharmaceutical drug development has been notably slower. Concerns surrounding data security, the complexity of AI systems, and the rigorous regulatory frameworks in this field have caused the pharmaceutical industry to approach these technologies with caution. For years, AI and machine learning (ML) were often dismissed as little more than advanced statistics with little practical value in drug development.

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Can the heart heal itself? New study says it can

Science Daily: Pharmacology News

Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

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Novo’s next-gen obesity drug misses expectations in closely watched trial

BioPharma Drive: Drug Pricing

Novo shares lost nearly a quarter of their value after an experimental combination treatment called cagrisema fell short of the bar set by executives.

Trials 290
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Could Olumiant Be A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful

Drugs.com

FRIDAY, Dec. 20, 2024 -- An existing drug might be able to treat an autoimmune disorder that causes dry eye, dry mouth, fatigue and muscle or joint pain. Baricitinib (Olumiant), a drug currently used to treat rheumatoid arthritis, appears to.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Growing safer spuds: Removing toxins from potatoes

Science Daily: Pharmacology News

Scientists have discovered a way to remove toxic compounds from potatoes and tomatoes, making them safer to eat and easier to store. The breakthrough could cut food waste and enhance crop farming in extreme environments, like outer space.

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More Trending

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Water and gruel -- not bread: Discovering the diet of early Neolithic farmers in Scandinavia

Science Daily: Pharmacology News

At a Neolithic settlement on the Danish island Funen dating back 5,500 years, archaeologists have discovered both grinding stones and grains from early cereals. However, new research reveals that the inhabitants did not use the stones to grind the cereal grains. Instead of making bread, they likely prepared porridge or gruel from the grains.

Research 273
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What's the Link Between Memory Problems and Sexism?

Drugs.com

FRIDAY, Dec. 20, 2024 -- Sexism is incredibly toxic to womens lives, resulting in lower pay, fewer career opportunities, worse health care and a greater risk of violence.It also can be toxic to their brain health, a new study says.U.S. women born i.

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Mysteries of icy ocean worlds

Science Daily: Pharmacology News

A study introduces a novel thermodynamic concept called the 'centotectic' and investigates the stability of liquids in extreme conditions -- critical information for determining the habitability of icy moons like Europa.

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Check Your Pantry, Lay's Classic Potato Chips Recalled Due to Milk Allergy Risk

Drugs.com

FRIDAY, Dec. 20, 2024 -- Holy chip! Frito-Lay has issued a limited recall of select 13-oz bags of Lays Classic Potato Chips due to the potential presence of undeclared milk, which could pose a serious health risk to individuals with a milk a.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Ionis gets a milestone approval; Another top FDA official to step down

BioPharma Drive: Drug Pricing

The clearance of Tryngolza gives Ionis its first wholly-owned, marketed medicine. Elsewhere, Robert Temple became the latest FDA leader to leave the agency, and two biotechs cut research deals.

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Norovirus Sickens Hundreds on Three Cruise Ships: CDC

Drugs.com

FRIDAY, Dec. 20, 2024 -- Just over 300 people have been sickened in norovirus outbreaks on three different cruise ships in December, new government data shows.This is the only month this year in which the U.S. Centers for Disease Control and.

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Microbiological Applications: Bacterial Metabolism | BMG LABTECH

BMG Labtech

Bacterial metabolism applications Bacterial metabolism spans the complex interconnected set of chemical reactions that support life in bacteria, ancient single-celled organisms that represent one of the most diverse forms of life on Earth. Bacterial metabolism is the foundation for bacterial growth and is inextricably linked to other organisms in the ecosystem.

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Who is At Risk For Cybercrime?

Drugs.com

FRIDAY, Dec. 20, 2024 -- Whos more likely to send money in response to a Nigerian princes email, or hand over a password in response to a phishing attempt?Young people are more likely to report -- and gripe about -- cybercrimes, but a new study sh.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Keypoint Newsletter: Introducing the New Fellows Class of 2025

keypoint

Meet the Keystone Symposia Fellows Class of 2025, a stellar group of post-doctoral fellows and early-career scientists who will take part in this prestigious mentorship program.

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A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful

Drugs.com

FRIDAY, Dec. 20, 2024 -- An existing drug might be able to treat an autoimmune disorder that causes dry eye, dry mouth, fatigue and muscle or joint pain.Baricitinib (Olumiant), a drug currently used to treat rheumatoid arthritis, appears to.

Disease 246
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Curves Module Insights

Collaborative Drug

Learn how CDD Vault is utilizing Curves to improve your drug discovery process.

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Supreme Court to Decide on South Carolina's Bid to Cut Funding for Planned Parenthood

Drugs.com

FRIDAY, Dec. 20, 2024 -- In a pivotal move, the United States Supreme Court announced Wednesday that it will review South Carolina's controversial decision to cut off state funding for Planned Parenthood clinics, which provide critical health.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Keypoint Newsletter: A Message from Our CEO

keypoint

Keystone Symposia CEO shares his first impressions, improvement and initiatives that will be implemented in 2025.

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Not Just Blabber: What Baby's First Vocalizations and Coos Can Tell Us

Drugs.com

FRIDAY, Dec. 20, 2024 -- A babys gentle murmurs and coos can melt even the stoniest heart.But those giggles and babbles are more than just music to a doting parents ears.These vocalizations actually are signs that a babys heart is working rhyth.

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Keypoint Newsletter: December 2024

keypoint

Checkout the December 2024 Keypoint Newsletter for the latest news and views from Keystone Symposia, including Fellows spotlights, our new partership with the Endocrine Society, Women in Science networking events, emerging topics conferences and conference highlights.

Science 105
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Antibiotics Do Not Increase Risks for Cognitive Decline, Dementia in Older Adults, New Data Says

Drugs.com

FRIDAY, Dec. 20, 2024 -- Seniors with an infection can take antibiotics without fear of harming their brain health.Antibiotics dont appear to increase the risk of cognitive decline or dementia in older adults, researchers report in the journal N.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Keypoint Newsletter: Fall 2024 Conference Highlights & Enhanced Programming

keypoint

We wrapped up the year with a handful of Fall conferences at home and abroad , spanning Colorado to California, Canada and Ireland. These meetings featured Keystone Symposia's signature emerging science and unpublished data, as well as career development and networking opportunities that are critical to the professional growth and success of our attendees.

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Discover Astellas’ differentiated approach to innovation partnerships

Fierce BioTech

As a global life sciences company, Astellas is passionate about partnering to advance life-changing treatments for patients.

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Optical density and absorbance measurements | BMG LABTECH

BMG Labtech

Absorbance measurements, often referred to as light absorbance, are so versatile and widespread that they are one of the first techniques many life science researchers encounter in a practical setting. Absorbance measurements are taken at a particular wavelength to determine the amount of light absorbed by a substance. Optical density is also widely used for many scientific applications.

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Some Abortion Pill Users Surprised By Pain, Study Says

Drugs.com

FRIDAY, Dec. 20, 2024 -- Abortion pills are safe and effective, but some pain will be part of the process for most women.However, many women are surprised by exactly how much pain is involved in a medication abortion, a new study says.Theyre f.

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Lycorine Suppresses Non‐Small‐Cell Lung Cancer Progression Through Activating STING Pathway and Stimulating an Antitumor Immune Response

Chemical Biology and Drug Design

Our results demonstrate the effects of LYD on cell viability, cell cycle, and apoptosis in NSCLC invitro and invivo models and explored its underlying mechanisms. Our findings suggest that LYD inhibited NSCLC cells growth by inducing G2/M arrest and subsequent apoptosis. It also inhibited the P70S6K and PS6 pathways. More interestingly, LYD also significantly activated the STING pathway in NSCLC, inducing CXCL10 and CCL5 expression, which may help overcome immunotherapy resistance.

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Dark energy 'doesn't exist' so can't be pushing 'lumpy' Universe apart

Science Daily: Pharmacology News

One of the biggest mysteries in science -- dark energy -- doesn't actually exist, according to researchers looking to solve the riddle of how the Universe is expanding. For the past 100 years, physicists have generally assumed that the cosmos is growing equally in all directions. They employed the concept of dark energy as a placeholder to explain unknown physics they couldn't understand, but the contentious theory has always had its problems.

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Covalent inhibitors of the RAS binding domain of PI3Ka impair tumor growth driven by RAS and HER2

Covalent Modifiers

Joseph E Klebba, Nilotpal Roy, Steffen M Bernard, Stephanie Grabow, Melissa A. Hoffman, Hui Miao, Junko Tamiya, Jinwei Wang, Cynthia Berry, Antonio Esparza-Oros, Richard Lin, Yongsheng Liu, Marie Pariollaud, Holly Parker, Igor Mochalkin, Sareena Rana, Aaron N. Snead, Eric J. Walton, Taylor E. Wyrick, Erick Aitichson, Karl Bedke, Jacyln C. Brannon, Joel M.

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First demonstration of quantum teleportation over busy Internet cables

Science Daily: Pharmacology News

Quantum teleportation could provide near-instant communication over long distances. But, inside Internet cables, photons needed for teleportation are lost within the millions of light particles required for classical communications. A new study quantified light scattering to find exact areas to place photons to keep them safe from other particles. The approach successfully worked in experiments carrying regular Internet traffic.

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