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Imagine you are building a Salesforce application and must ensure that users can only access specific fields based on their profiles or permission sets. You might wonder: can we control field-level security (FLS) from Apex? Explore this topic and understand the possibilities, challenges, and best practices. Understanding Field-Level Security in Salesforce Before we explore Apex, let’s first understand how Salesforce manages field-level security (FLS).
Results from a phase 1/2 clinical trial of a novel stem cell treatment for cornea injuries found 14 patients treated and tracked for 18 months had a more than 90% success rate at restoring the cornea's surface and improvements in vision. The procedure, called CALEC (cultivated autologous limbal epithelial cells) involves taking stem cells from a healthy eye, expanding it into a graft over several weeks, then transplanting it into a patient's damaged eye.
THURSDAY, March 6, 2025 -- GLP-1 drugs like Ozempic can help kidney transplant patients avoid organ failure and live longer, a new study suggests.The drugs help manage patients type 2 diabetes and promote weight loss, both of which improve the c.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
We reported a virtual screening workflow combining docking and MD simulations to achieve eight compounds for further enzymatic assay and ADMET profile prediction. The results indicated a candidate 2 with IC 50 values of 2.396 and 5.996M against LRRK2 and LRRK2 G2019S, respectively, implying the reliability of this approach. ABSTRACT Parkinson's disease (PD) is the second most common neurodegenerative disease but has limited medications.
Scientists have uncovered the mechanism behind how aspirin could reduce the metastasis of some cancers by stimulating the immune system. The scientists say that discovering the mechanism will support ongoing clinical trials, and could lead to the targeted use of aspirin to prevent the spread of susceptible types of cancer, and to the development of more effective drugs to prevent cancer metastasis.
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Scientists have uncovered the mechanism behind how aspirin could reduce the metastasis of some cancers by stimulating the immune system. The scientists say that discovering the mechanism will support ongoing clinical trials, and could lead to the targeted use of aspirin to prevent the spread of susceptible types of cancer, and to the development of more effective drugs to prevent cancer metastasis.
Marco Paolino, Giusy Tassone, Paolo Governa, Mario Saletti, Matteo Lami, Riccardo Carletti, Filippo Sacchetta, Cecilia Pozzi, Maurizio Orlandini, Fabrizio Manetti, Massimo Olivucci, and Andrea Cappelli ACS Medicinal Chemistry Letters 2025 DOI: 10.1021/acsmedchemlett.4c00479 The use of Targeted Covalent Inhibitors (TCIs) is an expanding strategy for the development of innovative drugs.
THURSDAY, March 6, 2025 -- Florida’s insurance regulator is demanding detailed prescription data on millions of patients, raising alarms over patient privacy. In January, the Florida Office of Insurance Regulation asked pharmacy benefit.
Synthesis, structureactivity relationship, targets, and anticancer activity of fused and substituted piperazines. ABSTRACT Cancer is an abnormal and uncontrolled proliferation of normal cells. The availability of safer anticancer drugs with exceptional selectivity for healthy cells and great efficacy against various cancer forms continues to be a significant obstacle.
Researchers explore the likelihood that Earth's climate, as affected by solar heat, plays a role in seismic activity. Using mathematical and computational methods, they analyzed earthquake data alongside solar activity records and surface temperatures on Earth and observed that when they included Earth surface temperatures into their model, the forecasting became more accurate, especially for shallow earthquakes.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
The Swiss pharma will base cardiometabolic drug research at the new Allston site. Elsewhere, AskBio advanced a gene therapy and Pfizer hired a scientist well versed in GLP-1 science.
WEDNESDAY, March 5, 2025 -- A measles outbreak in Texas has grown to 159 cases, and now the U.S. Centers for Disease Control and Prevention (CDC) has sent a team to help local health officials respond.The CDC announced the plan on X, explaining.
Dr. Adam J. Fein, president of Drug Channels Institute (DCI) and the author of Drug Channels , invites you to join him for DCIs new live video webinar: PBM Industry Update: Trends, Challenges, and What's Ahead This event will be broadcast live on Friday, April 4, 2025, from 12:00 p.m. to 1:30 p.m. ET This page describes the event and explains how to purchase a registration.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Optum, the pharmacy benefit manager owned by UnitedHealth Group, placed Journavx on some of its commercial formularies in an interim decision while a formal review continues.
TUESDAY, March 4, 2025 -- Continuous blood glucose monitors have been promoted as potentially life-changing for people with diabetes -- allowing real-time updates on blood sugar levels without the need for repeated finger pricks.But a new.
Lemmings We wrote recently about the lemming phenomena with respect to the bispecific modality combining VEGF pathway inhibition plus PD-1 pathway inhibition. Our hope is not all the lemmings dive off the cliff, however we are not optimistic. This does not mean that VEGF pathway inhibition should not be exploited this is obvious based on the synergy seen when approved VEGF pathway inhibitors are administered alongside approved PD-1 pathway inhibitors.
A newly developed pentanuclear iron complex can offer an efficient, stable, and cost-effective solution for water oxidation. By electrochemically polymerizing the complex, researchers have obtained a polymer-based catalyst, poly-Fe5-PCz, and achieved water oxidation with up to 99% Faradaic efficiency and exceptional stability, even under rigorous conditions.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
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WEDNESDAY, March 5, 2025 -- Over-the-counter drugs like aspirin or ibuprofen might help protect against dementia, a new study suggests.These NSAIDs (non-steroidal anti-inflammatory drugs) might help protect the brain by quelling inflammation that.
Breaking Down Barriers: The Power of Global Research Collaborations in Generic Drug Development As the world grapples with the complexities of healthcare, one thing is clear: the need for innovative solutions has never been more pressing. In the realm of generic drug development, international research collaborations are emerging as a game-changer. By pooling resources, expertise, and knowledge, researchers from around the globe can accelerate the discovery of life-saving treatments and make the
Researchers have enabled a man who is paralyzed to control a robotic arm through a device that relays signals from his brain to a computer. He was able to grasp, move and drop objects just by imagining himself performing the actions.
A licensing deal with Denmark’s Gubra gives the immunology giant control of an experimental therapy that could compete with drugs from Novo Nordisk, Eli Lilly and Zealand.
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We recently hosted our Q1 2025 Product Update Webinar, showcasing significant enhancements to CDD Vault's automation capabilities and inventory management system. The webinar demonstrated how these features streamline laboratory operations and CRO collaborations. Here's a summary of the key updates.
Until now, artificial gels have either managed to replicate high stiffness or natural skin's self-healing properties, but not both. Now, a team of researchers has developed a hydrogel with a unique structure that overcomes earlier limitations, opening the door to applications such as drug delivery, wound healing, soft robotics sensors and artificial skin.
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