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Sosei Heptares’ COVID-19 Program Identifies Potent Broad Spectrum Anti-Viral Small Molecules for Further Development

The Pharma Data

The Company is also aiming to leverage the highly conserved structure of the SARS-CoV-2 M pro protease as a basis for the design of novel oral small molecules against predicted future variants of SARS-CoV-2 and other related human viruses. View original content: [link]. SOURCE Sosei Heptares. Source link.

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Looking beyond traditional oncogenic pathways to break cancer resistance

Drug Target Review

At TOLREMO, we have developed a proprietary modular phenotypic screening platform that leverages transcriptional reprogramming events associated with non-genetic resistance to deliver new chemical scaffolds and identify novel resistance regulators. Inhibiting KDM5A, a regulator of cell proliferation, poses another interesting approach.

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GPU-Accelerated Molecular Dynamics Applications Help Fight COVID-19

Nvidia Developer: Drug Discovery

To help make the process for scientists more accessible, we’re spotlighting a few of the GPU-accelerated applications that developers can use right now in the fight against this virus. For example, events such as folding and docking can take micro- and milliseconds to occur.

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Aridis Pharmaceuticals to Present at the ROTH Capital Partners 2020 MedTech Innovation Forum on a COVID-19 Panel

The Pharma Data

Hasan Jafri , Chief Medical Officer of Aridis Pharmaceuticals, will be a speaker on a panel entitled “Direct Antivirals and Other Agents Against SARS-CoV2 Virus.” ” Panel: Direct Antivirals and Other Agents Against SARS-CoV2 Virus Date: Wednesday, October 28, 2020 Time: 10:30AM- 11:50AM ET.

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Pfizer and BioNTech receive CHMP positive opinion for COVID-19 vaccine booster in the European Union

The Pharma Data

A booster dose of the vaccine elicited significantly higher neutralizing antibody titers against the initial SARS-CoV-2 virus (wild type), as well as the Beta and Delta variants, when compared with the levels observed after the two-dose primary series.

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Aikido Pharma Secures Early Interest in Next Generation Radiotherapy

The Pharma Data

Convergent has identified certain small molecules that bind to PSMA, but at a different epitope than does CONV 01-?, Importantly, Convergent identified small molecules, with a current focus on the molecule PSMA I&T, that have different biodistributions in the body than does CONV 01-? . .

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Syros Announces Pricing of $75.6 Million Public Offering of Common Stock

The Pharma Data

Syros is redefining the power of small molecules to control the expression of genes. Any forward-looking statements contained in this press release speak only as of the date hereof, and Syros expressly disclaims any obligation to update any forward-looking statements, whether because of new information, future events or otherwise.