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What single cells are revealing about brain disorders

Drug Target Review

From maths and physics to molecular biology Schnall-Levin did not begin in the life sciences. “I I started looking around and getting interested in biology. I got my eyes opened to molecular biology, bioinformatics, computational biology and these emerging fields at the time.”

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Altasciences at ASGCT 2025: An Open Forum for All Things Gene and Cell Therapy | By Kaylyn Koenig

Alta Sciences

Altasciences at ASGCT 2025: An Open Forum for All Things Gene and Cell Therapy | By Kaylyn Koenig aasimakopoulos Thu, 07/10/2025 - 08:00 I recently returned from attending the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting.

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Organoids: the versatile platform for discovery and regeneration

Drug Target Review

Organoids will play increasingly crucial roles not only in research and diagnostics, but also in therapies to restore and enhance the human body. He received his BS in physics and biology from the University of Chicago and his PhD in molecular biology from the University of Pennsylvania. 2017;23(1):49-59.

Treatment 105
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Pain relief without the risk: why SRP-001 could change everything

Drug Target Review

Bazan sees it as part of a broader shift towards combination therapies – an approach that will likely define the next generation of pain management. Pain treatment, he says, will not be defined by a single breakthrough but by a diverse range of therapies that can be tailored to different patients and conditions. Dr Bazan holds a B.S.

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Time for change: non-human primates in drug research

Drug Target Review

Importantly, this roadmap complements earlier FDA initiatives supporting the use of NAMs, 8 signalling a sustained federal commitment to reducing animal use in science without compromising patient safety. To overcome these hurdles, stakeholders must invest in collaborative research, transparent data sharing and regulatory science.

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Automated red blood cell exchange: bridging treatment gaps in sickle cell disease care

Drug Target Review

Despite recent advances in gene therapy for sickle cell disease (SCD) , automated red blood cell exchange (aRBCX) remains a cornerstone therapy that plays a vital yet underutilised role in managing complications and enhancing quality of life for millions living with this devastating condition worldwide.

Disease 52
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A Visual Guide to Genome Editors

Codon

The treatment, now known as Casgevy, became the first CRISPR-based therapy to gain FDA approval, in 2023. Such off-target cuts are obviously a big concern when developing human therapies, because they can cause mutations that lead to cancer or other diseases. He earned his A.B.

DNA 81