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David Liu receives Breakthrough Prize in Life Sciences By Corie Lok April 5, 2025 Breadcrumb Home David Liu receives Breakthrough Prize in Life Sciences Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. In 2013, Broad founding director Eric S.
The breakthrough science focused on replicating heart tissues, bringing research closer to generating functional, bioprinted organs, which would have broad applications in disease modelling, drug screening and regenerative medicine.
MONDAY, May 5, 2025 Consuming too much cinnamon might affect how your body absorbs some medications, new research shows.The study published in the June issue of the journal Food Chemistry: Molecular Sciences looked at how cinnamon and its key.
Researchers in the field of exposomics explain how cutting-edge technologies are unlocking this biological archive, ushering in a new era of disease prevention and personalized medicine.
Doctors also wrestled with how best to use new bispecific antibodies, and expressed concern about looming cuts to science funding. Breast cancer study results impressed at this year’s meeting, but raised new questions.
Feng Zhang awarded the National Medal of Technology and Innovation By Corie Lok January 6, 2025 Breadcrumb Home Feng Zhang awarded the National Medal of Technology and Innovation Zhang and 22 other individuals received the USs highest honors for science and technology. By Broad Communications January 6, 2025 Credit: Ryan K.
State of the Birds Report, produced by a coalition of leading science and conservation organizations, reveals continued widespread declines in American bird populations across all mainland and marine habitats, with 229 species requiring urgent conservation action. The 2025 U.
If thats not compelling enough, space can at least offer a mental respite from our terrestrial woes no gravity, no tariffs, no anti-science agenda. Which begs the question, is space-based biomanufacturing science fiction or science fact? Science Fiction or Science Fact? Why Space, Why Drugs, and Why Now?
A 113-million-year-old hell ant that once lived in northeastern Brazil is now the oldest ant specimen known to science, finds a new report. The hell ant, which was preserved in limestone, is a member of Haidomyrmecinae -- an extinct subfamily that only lived during the Cretaceous period.
Smith identifies three key obstacles preventing broader acceptance of AI: Communication gaps : Pharmaceutical and computational science communities often struggle to understand each others technical languages, making collaboration difficult.
The literature review was conducted using four databases: Web of Science, ScienceDirect, Scopus, Embase, and Reaxys. This review delves into these emerging areas, highlighting how carprofen's molecular structure and derivatives can be leveraged to expand its therapeutic reach.
Funding This research is funded by the Eric and Wendy Schmidt Center at the Broad Institute, the National Institutes of Health, the National Science Foundation, the Burroughs Welcome Fund, the Searle Scholars Foundation, the Harvard Stem Cell Institute, the Merkin Institute, the Office of Naval Research, and the Department of Energy.
Zylberberg has built an impressive career at the intersection of science, technology, and business. Were developing user-friendly AI tools that dont require a PhD in data science to operate, she explains. In manufacturing, AI-driven automation can optimise workflows, reduce errors, and ensure compliance with regulatory standards.
A new paper , published today in Science , suggests a way forward. This is because the protein structural databases used to train these models consist overwhelmingly of structures gleaned from protein crystals or other “frozen” images. The resultant distortion has made computational enzyme design exceptionally difficult.
The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino.
Maintaining a healthy diet rich in plant-based foods, with low to moderate intake of healthy animal-based foods and lower intake of ultra-processed foods, was linked to a higher likelihood of healthy aging -- defined as reaching age 70 free of major chronic diseases and with cognitive, physical, and mental health maintained, according to a new study. (..)
A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the rare condition carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after birth, has responded positively to the treatment.
Archaeopteryx is the fossil that clearly demonstrated Darwin's views. It's the oldest known fossil bird, and it helps show that all birds -- including the ones alive today -- emerged from dinosaurs. And while the first Archaeopteryx fossil was found more than 160 years ago, scientists are continuing to learn new things about this ancient animal.
Psychology literature has shown that curiosity tends to decline with age. Psychologists shows one type of curiosity can increase well into old age, contradicting prior research. Older adults who maintain curiosity and want to learn new things relevant to their interests may be able to offset or even prevent Alzheimer's disease.
Astronomers have witnessed for the first time a violent cosmic collision in which one galaxy pierces another with intense radiation. Their results show that this radiation dampens the wounded galaxy's ability to form new stars.
Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement.
Short snouts and a flat profile -- within a span of 100 years, humans have significantly changed the shape of the skulls of German domestic pigs. This is likely down to new breeding practices introduced at the beginning of the 20th century.
New research shows that cyberbullying should be classified as an adverse childhood experience due to its strong link to trauma. Even subtle forms -- like exclusion from group chats -- can trigger PTSD-level distress. Nearly 90% of teens experienced some form of cyberbullying, accounting for 32% of the variation in trauma symptoms.
A tiny, four-fingered 'hand' folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, researchers report.
Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline.
Results from a phase 1/2 clinical trial of a novel stem cell treatment for cornea injuries found 14 patients treated and tracked for 18 months had a more than 90% success rate at restoring the cornea's surface and improvements in vision.
Evidence of a unique T cell may explain why urban children are more prone to allergies than rural children. Differences in the development of the gut microbiome may be an underlying cause.
Researchers have applied a visualization technique to depict the brain's activity related to visual perception as geometric patterns. They visualized different shapes as the ever-changing neuronal activity in the temporal and frontal lobes of the brain during object recognition and recalling memories.
Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions.
Until now, most research has used either generalized cell samples or organoids made from just one type of tropical fruit bat, and only from a single organ. But a breakthrough has arrived: a research team has now created the world's most comprehensive bat organoid platform.
The largest sample of galaxy groups ever detected has been presented by a team of international astronomers using data from the James Webb Space telescope (JWST) in an area of the sky called COSMOS Web.
Researchers have discovered a new class of materials -- called intercrystals -- with unique electronic properties that could power future technologies.
New research reveals mountain glaciers across the globe will not recover for centuries -- even if human intervention cools the planet back to the 1.5 C limit, having exceeded it.
A team was able to show that swimming movements are possible even without a central control unit. This not only explains the behavior of microorganisms, it could also enable nanobots to move in a targeted manner, for example to transport drugs to the right place in the body.
Astronomers searching for massive black holes shredding stars found one in an unusual place -- 2,600 light years from the core of a galaxy. The roque black hole may be from an earlier merger with another galaxy, or have been tossed out of the core after interacting with two other black holes.
Spring in the Arctic brings forth a plethora of peeps and downy hatchlings as millions of birds gather to raise their young. The same was true 73 million years ago, according to a new article. The paper documents the earliest-known example of birds nesting in the polar regions.
Animal abduction: Biologists documented five male capuchin monkeys carrying at least eleven different infant howler monkeys -- a behavior never before seen in wild primates.
Many an orange cat-affiliated human will vouch for their cat's, let's say, specialness. But now scientists have confirmed that there is, in fact, something unique about ginger-hued domestic felines.
A new study finds that if global warming exceeds the Paris Climate Agreement targets, the non-polar glacier mass will diminish significantly. However, if warming is limited to 1.5 degrees Celsius, at least 54 per cent could be preserved -- more than twice as much ice as in a 2.7 C scenario.
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