Science Daily: Pharmacology News

MARCH 18, 2025

For years, therapy dogs have ruled the world of animal-assisted services (AAS), offering stress relief to college students, hospital patients, and those in need of emotional support.

Therapies 294

Therapies Hospitals Research 294

Science Daily: Pharmacology News

JANUARY 2, 2025

This study marks an important step toward regenerative therapies to prevent heart failure. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement.

Therapies 311

Therapies Research 311

Science Daily: Pharmacology News

SEPTEMBER 25, 2024

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the new results of an international Phase III clinical trial.

Therapies 305

Therapies Clinical Trials International Trials 305

Science Daily: Pharmacology News

MAY 16, 2024

In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

Therapies 323

Therapies Engineering Disease Research 323

Science Daily: Pharmacology News

FEBRUARY 14, 2025

One day, researchers want to use switches of this kind to trigger cell therapies for various metabolic diseases. Researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

Therapies 278

Therapies Disease Research 278

Science Daily: Pharmacology News

APRIL 26, 2024

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high.

Therapies 323

Therapies Research 323

BioPharma Drive: Drug Pricing

OCTOBER 4, 2024

An experimental Alzheimer’s therapy from Cassava Sciences is still being tested in two Phase 3 studies, even as the company has come under regulatory scrutiny.

Trials 360

Trials Science Therapies 360

Science Daily: Pharmacology News

JUNE 5, 2024

A new clinical trial of five children with inherited deafness found administering gene therapy in both ears led to restored hearing and speech, and additional gains including sound source localization, ability to hear in noisy environments, and for two children, abillity to appreciate music.

Therapies 315

Therapies Trials Clinical Trials International 315

Drug Target Review

FEBRUARY 10, 2025

In the rapidly advancing field of cell therapies, Dr Jason Bock has emerged as a leader, known for his innovative approach to optimising the development process. With over 25 years of experience in therapeutics, Bock has played a pivotal role in shaping the future of cell therapies, particularly through his work at CTMC.

Therapies 64

Therapies Treatment Engineering Clinical Trials 64

Science Daily: Pharmacology News

JULY 12, 2024

Researchers have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells.

Therapies 234

Therapies Research 234

Science Daily: Pharmacology News

JUNE 12, 2024

In April, the FDA warned of risk of secondary cancers in people receiving CAR-T cell therapy. A large study now finds the risk is low and not related to the CAR-T cells.

Therapies 286

Therapies FDA 286

Science Daily: Pharmacology News

JULY 7, 2023

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF). According to new research, this form of medication improves the symptoms of CF in many patients.

Therapies 256

Therapies Research 256

Science Daily: Pharmacology News

AUGUST 30, 2023

A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.

Therapies 222

Therapies Clinical Trials Trials Disease 222

Science Daily: Pharmacology News

APRIL 2, 2025

Researchers have successfully developed a novel drug to restore vision. The treatment method restores vision through retinal nerve regeneration.

Therapies 292

Therapies Treatment Research Drugs 292

Science Daily: Pharmacology News

JANUARY 24, 2024

A novel gene therapy for hearing loss was administered to six children in China in a clinical trial. Each child had an inherited deafness caused by mutations in the OTOF gene, called DFNB9.

Therapies 220

Therapies Clinical Trials Trials Research 220

Science Daily: Pharmacology News

MAY 8, 2024

Investigators discovered that a subset of myeloid and lymphoid leukemias depend on a molecular complex called PI3Kgamma for survival.

Therapies 304

Therapies Clinical Trials Trials 304

Science Daily: Pharmacology News

AUGUST 31, 2023

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer. Scientists have demonstrated the potential efficacy of this approach a preclinical study.

Therapies 254

Therapies 254

Science Daily: Pharmacology News

OCTOBER 18, 2023

Results demonstrated the safety and preliminary efficacy of the novel gene therapy approach in high-grade glioma patients, with prolonged survival in a subgroup of recurrent GBM patients immunologically 'familiar' with the virus.

Therapies 221

Therapies Immune Response Research Virus 221

Broad Institute

JANUARY 9, 2025

Scientists engineer CRISPR enzymes that evade the immune system By Allessandra DiCorato January 9, 2025 Breadcrumb Home Scientists engineer CRISPR enzymes that evade the immune system The new genome-editing tools could lead to safer, more efficient gene therapies. Lisa Yang and Hock E. Tan Molecular Therapeutics Center at MIT.

Engineering 140

Engineering Immune Response Therapies DNA 140

Science Daily: Pharmacology News

AUGUST 30, 2023

Scientists have made a `paradigm shifting' discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer's disease and potentially Down syndrome.

Therapies 228

Therapies Disease 228

Science Daily: Pharmacology News

NOVEMBER 13, 2023

This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives. Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells.

Therapies 238

Therapies Disease Research 238

Science Daily: Pharmacology News

FEBRUARY 22, 2024

A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.

Therapies 226

Therapies Clinical Trials Treatment Disease 226

Science Daily: Pharmacology News

JUNE 21, 2024

Menthol sensing appeared long before cold sensing, suggesting distinct activation modes that can be disentangled, paving the way for new pain therapies without adverse thermal side effects.

Therapies 224

Therapies 224

Science Daily: Pharmacology News

AUGUST 9, 2023

Promising preclinical results show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer's disease.

Therapies 189

Therapies Disease 189

Science Daily: Pharmacology News

MAY 30, 2024

Scientists have found that statins -- commonly used cholesterol-lowering drugs -- may block a pathway that leads to the development of cancer in the context of chronic inflammation.

Therapies 303

Therapies Drugs 303

Science Daily: Pharmacology News

MARCH 13, 2025

Researchers devised a process to convert a skin cell directly into a neuron, eliminating the need to generate induced pluripotent stem cells. Such neurons could be used to treat spinal cord injuries or diseases such as ALS.

Engineering 285

Engineering Therapies Disease Research 285

BioPharma Drive: Drug Pricing

JUNE 3, 2024

With new modalities such as gene and cell therapies, RNA therapeutics, complex biologics and more, today’s science brings unprecedented opportunities to address diseases that have long remained out of reach.

Science 144

Science RNA Therapies Disease 144

Science Daily: Pharmacology News

JULY 31, 2023

Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS).

Therapies 190

Therapies Treatment 190

BioPharma Drive: Drug Pricing

MARCH 7, 2025

Elsewhere, AskBio advanced a gene therapy and Pfizer hired a scientist well versed in GLP-1 science. The Swiss pharma will base cardiometabolic drug research at the new Allston site.

Science 226

Science Therapies Drug Research Research 226

thought leadership

DECEMBER 9, 2024

Today's manufacturing environment is shaped by the rise of advanced therapies, including biologics, cell and gene therapies , and personalized medicine, each demanding highly specialized processes and controls.

Science 75

Science Compliance Regulations FDA 75

Science Daily: Pharmacology News

JULY 5, 2023

An antisense therapy restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome.

Protein Production 189

Protein Production Production Therapies RNA 189

Broad Institute

FEBRUARY 27, 2025

An ancient RNA-guided system could simplify delivery of gene editing therapies By Corie Lok February 27, 2025 Breadcrumb Home An ancient RNA-guided system could simplify delivery of gene editing therapies The programmable proteins are compact, modular, and can be directed to modify DNA in human cells. Lisa Yang and Hock E.

RNA 66

RNA Therapies DNA Virus 66

Drug Target Review

APRIL 30, 2025

In the rapidly evolving field of cell and gene therapy (CGT), the ability to manage complex biological data, optimise manufacturing processes, and accelerate drug discovery is crucial. Zylberberg has built an impressive career at the intersection of science, technology, and business.

Therapies 90

Therapies Drugs Clinical Trials Trials 90

Drug Target Review

MARCH 4, 2025

Phenomix Sciences , led by CEO Mark Bagnall, is using precision medicine to make treatments more targeted and effective. Phenomix Sciences, built on over a decade of clinical research at the Mayo Clinic, is disrupting this outdated approach. Meet Mark Bagnall Mark Bagnall currently serves as CEO of Phenomix Sciences, Inc.

Therapies 52

Therapies Treatment Clinical Trials Science 52

Science Daily: Pharmacology News

AUGUST 9, 2023

A study shows new steps toward more patients getting gene therapy.

Therapies 170

Therapies Research 170

Broad Institute

MAY 16, 2024

Gene therapy could potentially treat a range of severe genetic brain disorders, which currently have no cures and few treatment options. Since we came to the Broad we’ve been focused on the mission of enabling gene therapies for the central nervous system,” said Deverman, senior author on the study. “If

Therapies 137

Therapies FDA Approval Engineering Disease 137

Science Daily: Pharmacology News

APRIL 22, 2025

A new paper showcases the power of scalable protein engineering combined with machine learning to boost progress in the field of gene and cell therapy. Genome editing has advanced at a rapid pace with promising results for treating genetic conditions -- but there is always room for improvement.

Engineering 171

Engineering Research Therapies 171