addgene Blog

JUNE 27, 2023

In 2005, Boyden et al. described the first light-activated tool for controlling neuronal activity, channelrhodopsin-2 (ChR2), a blue light-activated cation channel, from the archaebacteria Chlamydomonas reinhardtii.

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ASPET

AUGUST 21, 2024

ICH established S7B and E14 guidelines in 2005 to prevent drug-induced torsade de pointes (TdP), effectively preventing the development of high-risk drugs. However, those guidelines unfortunately hampered the development of some potentially valuable drug candidates despite not being proven to be proarrhythmic.

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Compliance Pharmacokinetics Drugs Engineering 100

Drug Target Review

DECEMBER 29, 2023

2005 June 14 [cited 2023 October 13]; 10(3):283-290. Hoorn EJ, Gonzales PA, Gross P, Frokiaer J, Knepper MA, Pisitkun T et al. Prospects for urinary proteomics: Exosomes as a source of urinary biomarkers (Review Article). Nephrology [Internet]. Available from: [link]

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Cytel

NOVEMBER 1, 2023

It feels like just yesterday I attended my first PHUSE conference back in 2005 in Heidelberg, Germany. Fast forward 19 years, and the pharmaceutical industry landscape has undergone significant transformations.

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Pharmaceuticals Science 59

Alta Sciences

MARCH 4, 2025

Beatrice Setnik, PhD, joined Altasciences in 2019, and has been working in clinical drug development and abuse potential assessment since 2005. About the Author Beatrice Setnik, PhD, Chief Scientific Officer.

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Clinical Trials FDA Drug Development Trials 52

The Pharma Data

DECEMBER 3, 2020

Data were included for 1,018,136 live, singleton births in NHS hospitals between January 2005 and December 2006. 1, 2005, and March 31, 2015; 63 percent were emergency admissions. Victoria Coathup, Ph.D., The researchers identified 1,315,338 admissions between Jan.

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Hospitals Research 52

New Drug Approvals

APRIL 19, 2025

Baker JG (February 2005). 2016 Apr 25;80(5):1106-7 ^ “Rapibloc Summary of Product Characteristics” (PDF). Archived from the original (PDF) on 16 June 2019. Retrieved 11 September 2018. “The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors” British Journal of Pharmacology.

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Drug Target Review

FEBRUARY 12, 2024

I became a Director in 2005, responsible for the business’s continued growth from 7 initial founding members to 110 employees today. Communication was key – you can have the best technical team in the world, but without the right exposure they remain undiscovered, and it was important to get the message out there.

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International Science Laboratories Pharmaceuticals 111

FDA Law Blog: Biosimilars

SEPTEMBER 26, 2023

Since I entered the life sciences industry in 2005, I’ve respected HP&M and admired their expertise and elite standing,” said Grizzel. “I Ellison, HP&M’s Managing Director. I’m incredibly excited by the opportunity to work for HP&M and its amazing group of professionals.

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Marketing Compliance Science FDA 59

Common Sense for Drug Policy Blog

FEBRUARY 22, 2024

"Leshner and others argued that broad societal acceptance of the BDMA would deliver more effective addiction treatments that health insurers would fund and make more accessible to persons with addictions ( Volkow and Li, 2004 , Dackis and O’Brien, 2005 , Leshner, 1997 ).

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Disease Treatment Drugs 52

Broad Institute

JULY 10, 2023

Prior to joining the Harvard faculty, Gay was an assistant professor of political science at Stanford University from 2000 to 2005, and an associate professor (tenured) from 2005 to 2006. She is founding chair of the Inequality in America Initiative, a multidisciplinary effort launched in 2017. She earned a B.A.

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Science Government Engineering Research 52

LifeSciVC

DECEMBER 5, 2024

When I joined in 2005, the “patient” (Atlas) was undergoing surgery and we came out of the decade in 2010 with a small partnership, around one table, in one office in Cambridge. In 2014, we simplified further by focusing Atlas only on biotech.

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Marketing RNA Science Drugs 81

Metabolite Tales Blog

JULY 4, 2024

2005; 338(1):450-455. It is known that cytochrome P450s (CYPs) catalyse the oxidation of thiophenes with the simultaneous formation of two reactive intermediates, a thiophene-S-oxide and a thiophene epoxide (Dansette et al., References Dansette PM, Bertho G, Mansuy D. Biochem Biophys Res Commun. Drug Metabol Drug Interact.

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Drugs 52

The Pharma Data

OCTOBER 23, 2020

A pharmaceutical consultant at RMJ Consulting from 2008 to 2009, he found success as the vice president of global quality at Wyeth/FDAH from 2005 to 2008, the director of the Corporate Quality Center of Excellence of Abbott from 2001 to 2005, the director of corporate quality technology at Alcon Laboratories, Inc.,

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Pharmaceuticals International Engineering Science 52

Drug Target Review

MARCH 3, 2025

Meet Professor Jens Christian Schwamborn In 2002, Jens obtained a diploma in Biochemistry from the University of Witten/Herdecke in Germany and in 2005 a PhD in Biology from the University of Muenster in Germany. He worked as a postdoctoral researcher at the Institute for Molecular Biotechnology in Vienna, Austria.

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Disease Treatment Therapies Cell Biology 52

The Pharma Data

JANUARY 15, 2021

Marta Laskowski, from the University of Gothenburg in Sweden, and colleagues examined the association between cardiorespiratory fitness and risk for onset of psoriasis and psoriatic arthritis in a cohort of Swedish men in compulsory military service between 1968 and 2005.

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Disease Research 52

The Pharma Data

DECEMBER 30, 2020

from Drexel University in Philadelphia, and colleagues used data from 26,818 adult participants in the 2005 to 2018 U.S. WEDNESDAY, Dec. 14 in the American Journal of Preventive Medicine. Langellier, Ph.D., National Health and Nutrition Examination Survey to examine how allostatic load changes over time.

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Research 52

Common Sense for Drug Policy Blog

JANUARY 5, 2024

Its first major use was during World War II, when soldiers used it to boost their performance and alertness, and to suppress appetite (see also Braswell 2005 ; Rawson et al. Three years after the war, in 1948, the Japanese Ministry of Health prohibited the production of both tablet and powder form of methamphetamine.

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Pharmacy Regulations Production Marketing 52

FDA Law Blog: Biosimilars

AUGUST 21, 2023

Investigators also found that the pharmacy sold pseudoephedrine (“PSE”) products but failed to self-certify in violation of the Combat Methamphetamine Act of 2005 (“CMEA”). We note that in December 2020, the same U.S. 2, 2020 ( DOJ Press Release ). 21 U.S.C. § 830(e)(1)(B)(i).

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Pharmacy Regulations Production Laboratories 52

The Pharma Data

NOVEMBER 20, 2020

from the University of California Davis School of Medicine in Sacramento, and colleagues determined the cumulative incidence of VTE and major bleeding using California hospitalization data for 992 PCNSL patients using the California Cancer Registry (2005 to 2014). Anjlee Mahajan, M.D., percent, respectively. and 1.56, respectively).

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Hospitals Therapies Research 52

The Pharma Data

NOVEMBER 24, 2020

Renal Data System (2005 through 2014) to identify women who for the entire year were aged 15 to 44 years, on dialysis, and with Medicare as the primary payer. TUESDAY, Nov. 24, 2020 — Contraceptive use is low among women of reproductive age undergoing dialysis for end-stage kidney disease, according to a study published online Oct.

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Disease Research 52

The Pharma Data

JANUARY 15, 2021

Screening receipt remained below targets for breast and cervical cancer, with little change from 2005 to 2018. The researchers found that colorectal cancer test receipt neared the national Healthy People 2020 target in 2018 (66.9 percent of adults aged 50 to 75 years up to date with testing compared with target of 70.5 © 2021 HealthDay.

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Disease Research 52

The Pharma Data

DECEMBER 16, 2020

Yajun Liang, Ph.D., The researchers found that the fully adjusted hazard ratio of dementia was 0.25

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Research 52

The Pharma Data

DECEMBER 7, 2020

from Brigham and Women’s Hospital in Boston, and colleagues searched electronic medical records from six hospitals for isolated ulnar fractures in women aged 18 to 50 years from 2005 to 2019. Bharti Khurana, M.D., Radiographs were reviewed to determine fracture location, comminution, and displacement, as well as associated injuries.

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Hospitals Research 52

The Pharma Data

NOVEMBER 20, 2020

Similarly, more were trying to lose weight in 2015 versus 2005 (42.2 The researchers found that in 2015, 44.4 percent of participants had dieted and 60.5 percent had exercised to lose weight versus 37.7 percent, respectively, in 1986. to 2.59; lifetime dieting in girls: odds ratio, 1.23; 95 percent confidence interval, 0.91 to 1.66).

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Research 52

Agency IQ

AUGUST 18, 2023

The EPA initially adopted a carcinogen classification scheme in 1986 before revising it in 2005. However, not all substances classified under the 1986 framework were reclassified when the 2005 guidelines were published, meaning that both schemes still hold relevance today. by inhalation, but not ingestion).

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International Regulations Packaging Animal Testing 40

The Pharma Data

SEPTEMBER 23, 2020

In 2005, it cleared an anthrax vaccine for military personnel who were at high risk of being exposed to an anthrax attack. Back in July, the agency said that any vaccine would have to be 50% more effective compared to a placebo. . The FDA has only granted Emergency Use Authorization for a vaccine once before.

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Vaccine FDA FDA Approval Clinical Trials 52

The Pharma Data

NOVEMBER 27, 2020

Researchers analyzed data from more than 1 million children born in England in 2005 and 2006. But researchers said it has been unclear when the risk begins to drop or how it’s affected by a child’s gestational age at birth. On average, they were followed until they were just over 9 years old.

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Hospitals Research 52

Codon

JUNE 11, 2024

A partial solution to the problem came in 2005 when a team of researchers at the Scripps Institute found a “hacky” way to slow down the speed of nucleotides. Their solution was to fuse hairpins, little loops made from RNA or DNA, at various positions along the DNA strand that was being sequenced.

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The Pharma Data

AUGUST 3, 2021

The Gilead Foundation, established in 2005, builds on the company’s longstanding commitment to supporting underserved communities around the world. (Nasdaq: GILD) today announced a more than $200 million endowment to the Gilead Foundation to further the company’s vision of creating a healthier world for all people.

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Science International Disease 52

The Pharma Data

MARCH 13, 2021

She then received a Master in Electrical Engineering from the California Institute of Technology in 2003, and a PhD in Electrical Engineering in 2005. Fei-Fei Li studied Physics, Computer Science and Engineering at Princeton University, where she gained a B.A.

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International Engineering Science Marketing 52

Drug Target Review

FEBRUARY 7, 2024

Wong represented the US in the NSF-MEXT US-Japan Young Scientist symposium on Nanobiotechnology (2005), the Taipei Academia Sinica International Workshop on Soft Matter and Biophysics (2007), and the NSF-DST US-India Nanoscience & Engineering Workshop (2008). He currently serves on the Editorial Board of Physical Review E.

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RNA Virus Immune Response Engineering 69

New Drug Approvals

SEPTEMBER 8, 2024

. “MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin” The Journal of Clinical Endocrinology and Metabolism. 96 (9): 2889–2897. doi : 10.1210/jc.2011-1061. FDA” (Press release).

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FDA Licensing Licensing FDA Approval 62

Drug Target Review

APRIL 9, 2024

In 2005, he joined CNIO to lead the Genomic Instability Group where he has been ever since. Oscar Fernandez-Capetillo did his PhD in the University of The Basque Country working with mouse models of autoimmunity with Dr Ana Zubiaga.

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RNA Cell Biology Clinical Development Disease 64

Common Sense for Drug Policy Blog

SEPTEMBER 15, 2023

Goofball’ was originally a term for barbiturate-type drugs with the earliest mention in the literature as heroin-methamphetamine injection in 2005 [ 17 ]. Supply changes have played a part in widespread distribution of ‘ice’ or ‘cream’, a more potent and lower price Mexican-sourced methamphetamine supplanting the domestic product [ 10 , 16 ].

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Production Drugs Research 40

The Pharma Data

NOVEMBER 26, 2020

Dr. Sushil Gupta founded Enova Illumination in 2005 after discovering a need for a new LED portable technology – one that would remove the restraint and restriction of fiber optic surgical headlight systems. About Enova Illumination.

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Doctors Production 52

FDA Law Blog: Drug Discovery

JUNE 11, 2023

This Draft Guidance, in part, replaces a 2005 guidance titled “How to Comply with the Pediatric Research Equity Act.”

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