Drug Target Review

FEBRUARY 28, 2024

Over the past 25 years, T-cell therapies have gained significant ground in the treatment of cancer. Preclinical research on γδ T cells has made great strides since the cells were first identified in the 1980s, with γδ T-cell therapies from several companies, including IN8bio, now in or nearing clinical trials for various cancers.

Therapies 105

Therapies Engineering Molecular Biology Science 105

New Drug Approvals

JUNE 26, 2025

Ma S, Gisselmann G, Vogt-Eisele AK, Doerner JF, Hatt H (October 2008). Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. 2008 Oct;21(4):370-8. 3] It is slightly less potent as a TRPM8 activator compared to icilin , but is a much more selective TRPM8 ligand when compared to menthol. [4]

FDA 48

FDA Small Molecule Clinical Trials FDA Approval 48

The Pharma Data

MARCH 2, 2021

Boehringer Ingelheim and Gubra today announced a new research and licensing agreement focused on the identification and validation of targets and innovative peptide compounds for the treatment of obesity. Our mission is to create breakthrough therapies that change lives. Financial terms of the new agreement are not disclosed.

Treatment 52

Treatment Bioinformatics Clinical Development Therapies 52

NIH Director's Blog: Drug Development

JUNE 14, 2016

The study, which analyzed vast troves of genomic and clinical data collected over many years from more than 50,000 people with and without diabetes, indicates that anti-diabetes therapies that lower glucose by targeting the product of a specific gene, called GLP1R , are unlikely to boost the risk of cardiovascular disease. December 2008. [2]

Drugs 52

Drugs Disease Drug Development Clinical Trials 52

The Pharma Data

NOVEMBER 5, 2020

Velders is presently chairman of HollandBIO, the association of Dutch biotech companies, and provides years of experience, specifically in the cell and gene therapy areas. Taveras will lead all research and non-clinical development functions supporting the company’s pipeline of investigational therapies.

Analytical Chemistry 40

Analytical Chemistry Pharmaceuticals Small Molecule Therapies 40

New Drug Approvals

APRIL 19, 2025

New Drug Therapy Approvals 2024 (PDF). “Metoprolol Therapy and CYP2D6 Genotype” In Pratt VM, McLeod HL, Rubinstein WS, et al. . ^ Jump up to: a b c d [link] ^ “List of nationally authorised medicinal products Active substance: landiolol” (PDF). Procedure no.: PSUSA/00010570/201802. Retrieved 12 October 2024.

FDA 62

FDA Clinical Trials Treatment Trials 62

LifeSciVC

OCTOBER 28, 2024

In-licensing molecules from other players, due to a partner’s strategic shifts, budget challenges, or geographic access, can be a great way to jumpstart early stage companies around more advanced assets. That deal catalyzed it’s next financing and IPO… but the asset eventually failed. Intellia, Kymera , Dyne, Replimune, etc).

Marketing 106

Marketing Licensing Licensing Targeted Protein Degradation 106